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Autor:
Agata Korlatowicz, Magdalena Kolasa, Paulina Pabian, Joanna Solich, Katarzyna Latocha, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5941 (2023)
Wistar-Kyoto rats (WKY), compared to Wistar rats, are a well-validated animal model for drug-resistant depression. Thanks to this, they can provide information on the potential mechanisms of treatment-resistant depression. Since deep brain stimulatio
Externí odkaz:
https://doaj.org/article/113f148fcc1843ceaba7572028cfd97f
Autor:
Agata Kowalik, Mateusz Majerek, Krzysztof Mrowiec, Joanna Solich, Agata Faron-Górecka, Olga Woźnicka, Marta Dziedzicka-Wasylewska, Sylwia Łukasiewicz
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 749 (2022)
Targeted therapy uses multiple ways of ensuring that the drug will be delivered to the desired site. One of these ways is an encapsulation of the drug and functionalization of the surface. Among the many molecules that can perform such a task, the pr
Externí odkaz:
https://doaj.org/article/1c476bb4c2e74ce4b69318b5de44fd7c
Autor:
Agata Korlatowicz, Maciej Kuśmider, Marta Szlachta, Paulina Pabian, Joanna Solich, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12203 (2021)
Background: Cognitive disorders associated with schizophrenia are closely linked to prefrontal cortex (PFC) dysfunction. Administration of the non-competitive NMDA receptor antagonist ketamine (KET) induces cognitive impairment in animals, producing
Externí odkaz:
https://doaj.org/article/bdffb22fddcf4d70b777e83dfe97f5e5
Autor:
Joanna Solich, Magdalena Kolasa, Agata Faron-Górecka, Jacek Hajto, Marcin Piechota, Marta Dziedzicka-Wasylewska
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9439 (2021)
Three strains of mice with various susceptibilities to restraint stress (RS), i.e., mice with a knocked out norepinephrine transporter gene (NET-KO), SWR/J and C57BL/6J (WT) mice were shown to serve as a good model to study the molecular mechanisms u
Externí odkaz:
https://doaj.org/article/fa41bb42429d4b7eb018d9e50f54ff7b
Publikováno v:
Cells, Vol 10, Iss 7, p 1630 (2021)
Long-lasting stress factors, both biological and psychological, are commonly accepted as the main cause of depressive disorders. Several animal models, using various stressful stimuli, have been used to find biochemical and molecular alterations that
Externí odkaz:
https://doaj.org/article/7d1e05abf6554c74a1724552179e406e
Restraint Stress in Mice Alters Set of 25 miRNAs Which Regulate Stress- and Depression-Related mRNAs
Autor:
Joanna Solich, Maciej Kuśmider, Agata Faron-Górecka, Paulina Pabian, Marta Dziedzicka-Wasylewska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9469 (2020)
In the present study, we aim to identify the effect of restrain stress (RS) on the expression of miRNAs in mouse serum. We used three genotypes of animals (mice with knock-out of the gene-encoding norepinephrine transporter, NET-KO; C57BL/6J, and SWR
Externí odkaz:
https://doaj.org/article/6077aa0282064ca9a48a4b32d41a3ca5
Autor:
Agata Korlatowicz, Paulina Pabian, Joanna Solich, Magdalena Kolasa, Katarzyna Latocha, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka
Abstract The mechanisms of treatment-resistant depression (TRD) are not clear and are difficult to study. An animal model resembling human TRD is the Wistar Kyoto rat strain. In the present study, we focused on selecting miRNAs that differentiate rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fddf455bf7f4d40235d1b582aed8ed
https://ruj.uj.edu.pl/xmlui/handle/item/312480
https://ruj.uj.edu.pl/xmlui/handle/item/312480
Autor:
Joanna Solich, Maciej Kuśmider, Agata Faron-Górecka, Paulina Pabian, Magdalena Kolasa, Beata Zemła, Marta Dziedzicka-Wasylewska
Publikováno v:
Cells, Vol 9, Iss 4, p 917 (2020)
In the present study, we used three strains of mice with various susceptibility to stress: mice with knock-out of the gene encoding norepinephrine transporter (NET-KO), which are well characterized as displaying a stress-resistant phenotype, as well
Externí odkaz:
https://doaj.org/article/13a3b204c6544d8bbb2c25706edddd75
Autor:
Marta Szlachta, Maciej Kuśmider, Paulina Pabian, Joanna Solich, Magdalena Kolasa, Dariusz Żurawek, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
G-protein–coupled receptor (GPCR) heterodimers are new targets for the treatment of schizophrenia. Dopamine D2 receptors and serotonin 5-HT1A and 5-HT2A receptors play an important role in neurotransmission and have been implicated in many human ps
Externí odkaz:
https://doaj.org/article/f47e84f4006f4a30ba9b60518edb39e0