Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth.

Autor: Lisa N Glass, Ganduri Swapna, Sivagami Sundaram Chavadi, JoAnn M Tufariello, Kaixia Mi, Joshua E Drumm, TuKiet T Lam, Guofeng Zhu, Chenyang Zhan, Catherine Vilchéze, Jesus Arcos, Yong Chen, Lijun Bi, Simren Mehta, Steven A Porcelli, Steve C Almo, Syun-Ru Yeh, William R Jacobs, Jordi B Torrelles, John Chan

Publikováno v: PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)

We have previously shown that the Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth and may be required for the establishment of tuberculous persistence. Here, yeast two-hybrid and affinity chromatography exper

Externí odkaz: https://doaj.org/article/6d48c6ed73d94b888c9e8814f3059ad9

COVID-19 Vaccine-Induced Lichenoid Eruptions—Clinical and Histopathologic Spectrum in a Case Series of Fifteen Patients with Review of the Literature

Autor: Yonatan K. Sapadin, Elazar Mermelstein, Robert G. Phelps, Christopher F. Basler, JoAnn M. Tufariello, Mark G. Lebwohl

Publikováno v: Vaccines
Volume 11
Issue 2
Pages: 438

Lichen planus is a distinctive mucocutaneous disease with well-established clinical and histopathologic criteria. Lichenoid eruptions closely resemble lichen planus and may sometimes be indistinguishable from it. Systemic agents previously associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fa235196f594d38ca173405b860275

Mechanisms of anti-vesicular stomatitis virus activity of deazaneplanocin and its 3-brominated analogs

Autor: Stewart W. Schneller, Lin Wang, Caroline G. Williams, Chong Liu, JoAnn M. Tufariello, Christopher F. Basler, Sudip Khadka, Joyce Sweeney Gibbons

Publikováno v: Antiviral Res

3-deazaneplanocin A (DzNep) and its 3-brominated analogues inhibit replication of several RNA viruses. This antiviral activity is attributed to inhibition of S-adenosyl homocysteine hydrolase (SAHase) and consequently inhibition of viral methyltransf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95dc9e12116b20c69abe2e9324eeca6d
https://doi.org/10.1016/j.antiviral.2021.105088

Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4+ T-cell activation

Autor: Joel D. Ernst, Patricia S. Grace, Thais Klevorn, Aleena Zahra, Alka Mehra, William R. Jacobs, Heidi S. Park, Cynthia Portal-Celhay, Jennifer A. Philips, Smita Srivastava, JoAnn M. Tufariello

Publikováno v: Nature microbiology, vol 2, iss 2

Mycobacterium tuberculosis (Mtb) establishes a persistent infection, despite inducing antigen-specific T-cell responses. Although T cells arrive at the site of infection, they do not provide sterilizing immunity. The molecular basis of how Mtb impair

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2ba0de5de9045d064426f74afbc887
https://europepmc.org/articles/PMC5453184/

Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis

Autor: Romain Veyron-Churlet, Laurent Kremer, Catherine Vilchèze, Virginie Molle, Jade Leiba, Grégory Baronian, Séverine Carrère-Kremer, Travis Hartman, JoAnn M. Tufariello, David Alland, Sangeeta Tiwari, Yann Guérardel, Lionel Mourey, Brian Weinrick, Xavier Trivelli, Shubhada Shenai, William R. Jacobs

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2014, 10 (5), pp.e1004115. ⟨10.1371/journal.ppat.1004115⟩
PLoS Pathogens, 2014, 10 (5), pp.e1004115. ⟨10.1371/journal.ppat.1004115⟩
PLoS Pathogens, Vol 10, Iss 5, p e1004115 (2014)

Mycobacterium tuberculosis bacilli display two signature features: acid-fast staining and the capacity to induce long-term latent infections in humans. However, the mechanisms governing these two important processes remain largely unknown. Ser/Thr ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606d40768b954af7fdc227ec941a187b
https://hal.archives-ouvertes.fr/hal-03002975/document