Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Joann Lim"'
Autor:
Timothy P. DiPeri, Mehmet Demirhan, Daniel D. Karp, Siqing Fu, David S. Hong, Vivek Subbiah, Joann Lim, Leomar Y. Ballester, Jean H. Tayar, Maria E. Suarez-Almazor, Milind Javle, Funda Meric-Bernstam
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 26-30 (2022)
Intrahepatic cholangiocarcinoma is a rare malignancy, which is rich in actionable alterations. Genomic aberrations in the mitogen-activated protein kinase (MAPK) pathway are common, and BRAF exon 15 p.V600E mutations are present in 5–7% of biliary
Externí odkaz:
https://doaj.org/article/be1451dee7c448a48031e47750b7ece3
Phase I clinical trial of combination imatinib and ipilimumab in patients with advanced malignancies
Autor:
Matthew J. Reilley, Ann Bailey, Vivek Subbiah, Filip Janku, Aung Naing, Gerald Falchook, Daniel Karp, Sarina Piha-Paul, Apostolia Tsimberidou, Siqing Fu, JoAnn Lim, Stacie Bean, Allison Bass, Sandra Montez, Luis Vence, Padmanee Sharma, James Allison, Funda Meric-Bernstam, David S. Hong
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-10 (2017)
Abstract Background Imatinib mesylate can induce rapid tumor regression, increase tumor antigen presentation, and inhibit tumor immunosuppressive mechanisms. CTLA-4 blockade and imatinib synergize in mouse models to reduce tumor volume via intratumor
Externí odkaz:
https://doaj.org/article/ca9a3138c3d54581961712de6d0fff52
Autor:
David S. Hong, Michael A. Curran, Kimal Rajapakshe, Ly M. Nguyen, Di Nguyen, Hira Zain, Elizabeth Sumner, Funda Meric-Bernstam, JoAnn Lim, Thomas F. Wilson, Eric T. Williams, Jack P. Higgins, Cristian Coarfa, Priya Bhosale, Vivek Subbiah, Timothy A. Yap, Ecaterina E. Dumbrava, Siqing Fu, Shubham Pant, Jordi Rodon, Daniel Karp, Sarina Piha-Paul, Coline A. Couillault, Priyamvada Jayaprakash, Aparna Hegde
Compilation of supplemental tables and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b735def399b806d88f9c72e98f39df
https://doi.org/10.1158/1078-0432.22479855.v1
https://doi.org/10.1158/1078-0432.22479855.v1
Autor:
Jordi Rodon, Joann Lim, Elizabeth A. Sumner, Hira Zain, Di Nguyen, Jack P. Higgins, Vivek Subbiah, Funda Meric-Bernstam, Eric T Williams, Coline Agnes Couillault, Siqing Fu, Timothy A. Yap, Kimal Rajapakshe, Aparna Hegde, Sarina Anne Piha-Paul, Shubham Pant, Michael A. Curran, Priya Bhosale, Priyamvada Jayaprakash, David S. Hong, Thomas F. Wilson, Daniel D. Karp, Ecaterina Ileana Dumbrava, Ly M. Nguyen, Cristian Coarfa
Publikováno v:
Clin Cancer Res
Purpose: As hypoxia can mediate resistance to immunotherapy, we investigated the safety, tolerability, and efficacy of combining evofosfamide, a prodrug that alleviates hypoxia, with ipilimumab, an immune checkpoint inhibitor, in immunologically “c
Autor:
Björn Busse, Kathrin Mletzko, Nathalie Bravenboer, Maaike Schilperoort, Leo van Ruijven, Patrick C.N. Rensen, Sander Kooijman, Joann Lim, Jan Kroon, Elizabeth M. Winter
Publikováno v:
FASEB Journal, 34(1), 1052-1064. FEDERATION AMER SOC EXP BIOL
The FASEB Journal, 34(1), 1052-1064. FASEB
Schilperoort, M, Bravenboer, N, Lim, J, Mletzko, K, Busse, B, van Ruijven, L, Kroon, J, Rensen, P C N, Kooijman, S & Winter, E M 2020, ' Circadian disruption by shifting the light-dark cycle negatively affects bone health in mice ', The FASEB Journal, vol. 34, no. 1, pp. 1052-1064 . https://doi.org/10.1096/fj.201901929R
The FASEB Journal, 34(1), 1052-1064. FASEB
Schilperoort, M, Bravenboer, N, Lim, J, Mletzko, K, Busse, B, van Ruijven, L, Kroon, J, Rensen, P C N, Kooijman, S & Winter, E M 2020, ' Circadian disruption by shifting the light-dark cycle negatively affects bone health in mice ', The FASEB Journal, vol. 34, no. 1, pp. 1052-1064 . https://doi.org/10.1096/fj.201901929R
The past decade, it has become evident that circadian rhythms within metabolically active tissues are very important for physical health. However, although shift work has also been associated with an increased risk of fractures, circadian rhythmicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54a8a2df24893c6172de3f71b72c676
http://hdl.handle.net/1887/3181531
http://hdl.handle.net/1887/3181531
Autor:
Elizabeth M. Winter, S. Kooijman, Patrick C N Rensen, Jan Kroon, Maaike Schilperoort, Leo van Ruyven, Nathalie Bravenboer, Joann Lim
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Acta Neurochirurgica, 161(2), 263-269. SPRINGER WIEN
BackgroundIn patients with persistent symptoms of meralgia paresthetica, a neurectomy of the lateral femoral cutaneous nerve (LFCN) can be performed to alleviate pain symptoms. The neurectomy procedure can be performed either as a primary procedure o
Autor:
Filip Janku, Jennifer J. Wheler, Michael J. Wallace, Savita Bidyasar, Joann Lim, David S. Hong, Aung Naing, Razelle Kurzrock, Siqing Fu, Sarina Anne Piha-Paul, Rabih Said, Apostolia Maria Tsimberidou, Bryan K. Kee
Publikováno v:
Investigational new drugs, vol 33, iss 4
Background Liver metastases are associated with a poor prognosis. We investigated the use of hepatic arterial infusion (HAI) of irinotecan combination therapy in patients with liver metastases. Patients and methods Patients with histologically confir
Autor:
Luis H. Camacho, Siqing Fu, David C. Madoff, Razelle Kurzrock, Sheila Garcia, Chaan S. Ng, Joann Lim, David S. Hong, Isis Gayed, Amar M. Panchal
Publikováno v:
Clinical Colorectal Cancer. 9:311-314
This pilot clinical trial explored the feasibility, safety, and efficacy of regional hepatic therapy combined with systemic anticancer agents in patients with refractory solid tumors and extensive unresectable liver involvement, including those with
Autor:
Aung Naing, Daniel D. Karp, Jennifer J. Wheler, Vivek Subbiah, Jorge Bellido, David S. Hong, Filip Janku, Ralph Zinner, Bettzy Stephen, Gerald Steven Falchook, Razelle Kurzrock, Heloisa Veasey Rodrigues, Danxia Ke, Apostolia Maria Tsimberidou, Joann Lim, Siqing Fu, Sarina Anne Piha-Paul
Publikováno v:
Investigational new drugs. 33(3)
Purpose Combining agents that block both the VEGF and PI3K/AKT/mTOR pathways may be synergistic. We explored a novel dosing schedule to assess safety, toxicity and activity in patients with advanced solid tumors. Patients and Methods Patients with re