Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Joann Labruyere"'
Autor:
Chainllie Young, Kevin A. Roth, Barbara J. Klocke, Tim West, David M. Holtzman, Joann Labruyere, Yue-Qin Qin, Krikor Dikranian, John W. Olney
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 608-614 (2005)
Acute, transient exposure to ethanol causes a widespread pattern of caspase-3 activation and neuroapoptosis in the developing rodent brain. To determine whether caspase-3 activation is an essential step in ethanol-induced developmental neuroapoptosis
Externí odkaz:
https://doaj.org/article/ddbf78aae8964682938b87f19d085287
Autor:
Krikor Dikranian, Masahiko J. Ishimaru, Tatyana Tenkova, Joann Labruyere, Y.Q. Qin, Chrysanthy Ikonomidou, John W. Olney
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 359-379 (2001)
Apoptosis is a word originally introduced by Kerr, Wyllie, and colleagues for a cell death process they defined in terms of its ultrastructural appearance in nonneuronal cells from various tissues. There are very few studies providing detailed ultras
Externí odkaz:
https://doaj.org/article/00514373bd4744f38c0a5af8602fe518
Autor:
Yukitoshi Izumi, Charity O. Kirby-Sharkey, Ann M. Benz, Joann Labruyere, Madelon T. Price, David F. Wozniak, Charles F. Zorumski, John W. Olney
Publikováno v:
Neurobiology of Disease, Vol 2, Iss 3, Pp 139-144 (1995)
We have found that the rat retina can be isolated atraumatically and incubatedex vivofor up to 24 h without showing signs of histological deterioration, and that retinas from adult or aged rats can be isolated as successfully as those from immature r
Externí odkaz:
https://doaj.org/article/ef525e05c6e0437c8eb72d01db64dc7e
Autor:
Vesna Jevtovic-Todorovic, Yue-Qin Qin, Haihui Wang, Tatyana Tenkova, Joann Labruyere, John W. Olney, Chainllie Young
Publikováno v:
British Journal of Pharmacology. 146:189-197
Recently, it was reported that anesthetizing infant rats for 6 h with a combination of anesthetic drugs (midazolam, nitrous oxide, isoflurane) caused widespread apoptotic neurodegeneration in the developing brain, followed by lifelong cognitive defic
Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures
Publikováno v:
Developmental Brain Research. 155:1-13
For three decades since the fetal alcohol syndrome (FAS) was first described, researchers have been keenly interested in understanding the mechanism(s) by which ethanol damages or disrupts development of the human fetal brain. It has been reported re
Autor:
John W. Olney, Junjeong Choi, Kevin A. Roth, Tatyana Tenkova, David M. Holtzman, Chainllie Young, Yue-Qin Qin, Joann Labruyere, Barbara J. Klocke
Publikováno v:
Cell Death & Differentiation. 10:1148-1155
A single episode of ethanol intoxication triggers widespread apoptotic neurodegeneration in the infant rat or mouse brain. The cell death process occurs over a 6-16 h period following ethanol administration, is accompanied by a robust display of casp
Autor:
Chrysanthy Ikonomidou, Yue-Qin Qin, Masahiko Ishimaru, Krikor Dikranian, Joann Labruyere, John W. Olney, Tatyana Tenkova
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 359-379 (2001)
Apoptosis is a word originally introduced by Kerr, Wyllie, and colleagues for a cell death process they defined in terms of its ultrastructural appearance in nonneuronal cells from various tissues. There are very few studies providing detailed ultras
Autor:
Ann Benz, John W. Olney, Yukitoshi Izumi, Seth B. Hammerman, Joann Labruyere, Charles F. Zorumski
Publikováno v:
Experimental Eye Research. 70:191-198
In histological studies using retinas, eyes are commonly fixed with aldehyde derivatives administered by immersion or perfusion. However, the histology of rat retinas chemically fixed as a whole eye is typically inferior to the histology of retinas t
Publikováno v:
Pediatric Research. 39:1020-1027
Recent evidence implicates the endogenous excitatory neurotransmitters, glutamate (Glu) and aspartate, in the pathophysiology of traumatic injury in the adult CNS, but it is not known whether similar excitotoxic mechanisms mediate traumatic injury in
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 55:211-224
A superoxide dismutase 1 (SOD-1) genetic defect has been identified in familial amyotrophic lateral sclerosis (ALS) and motor neuron degeneration has been described in SOD-1 transgenic mice. Because an excitotoxic mechanism has been implicated in ALS