Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joann J. Geer"'
Publikováno v:
Neuroscience Letters. 158:97-100
High-threshold neuronal voltage-sensitive Ca 2+ channels (VSCCs) have been classified into at least three subtypes, including L, N, and P, based on biophysical and pharmacological criteria. We examined K + -induced 45 Ca 2+ flux into rat neocortical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2cf96f0d06a1bb5c9247fad4343fac9
https://doi.org/10.1016/0304-3940(93)90621-q
https://doi.org/10.1016/0304-3940(93)90621-q
Publikováno v:
Neuroscience Letters. 145:197-200
Glutamate excites receptors located on neurons that cause calcium and sodium influx involved in excitatory synaptic transmission. During ischemia, excess glutamate is present in the extracellular space of brain tissue, leading to abnormal levels of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9618ea4244362b21046022eca2bae38
https://doi.org/10.1016/0304-3940(92)90021-x
https://doi.org/10.1016/0304-3940(92)90021-x
Autor:
David J. Dooley, Charles Taylor, David M. Rock, Sally J. Stoehr, Lain-Yen Hu, George P. Miljanich, Elizabeth Millerman, Joann J. Geer, Susan M. Lotarski, Mark G. Vartanian, Balazs G. Szoke, Michael Francis Rafferty, R. Todd Ryder
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(15)
Selective N-type voltage sensitive calcium channel (VSCC) blockers have shown efficacy in several animal models of stroke and pain. In the process of searching for small molecule N-type calcium channel blockers, we have identified a series of N-methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e325778df2c038aa46c8d2093a6fa49
https://pubmed.ncbi.nlm.nih.gov/10465535
https://pubmed.ncbi.nlm.nih.gov/10465535
Publikováno v:
The Role of Neurotransmitters in Brain Injury ISBN: 9781461365280
Glutamate is widely recognized as an excitotoxic neurotransmitter in the brain. Abundant evidence indicates that glutamate is released in large concentrations during ischemia, abnormally activating glutamate receptors and causing calcium influx that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a2837434642a0db1a5cf083db9c3bc
https://doi.org/10.1007/978-1-4615-3452-5_9
https://doi.org/10.1007/978-1-4615-3452-5_9
Publikováno v:
Life Sciences. 33:369-372
Clonidine, an alpha 2 adrenoreceptor agonist, is used to treat opiate dependent individuals who are experiencing the signs and symptoms of withdrawal. Changes in the apparent number of alpha 2 adrenoreceptors in specific areas of the rat brain have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c159069e0538120c6bc498cd58ee9ff6
https://doi.org/10.1016/0024-3205(83)90519-2
https://doi.org/10.1016/0024-3205(83)90519-2