Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joann B Powell"'
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179844 (2017)
Altered c-Src activity has been strongly implicated in the development, growth, progression, and metastasis of human cancers including prostate cancer. Src is known to regulate several biological functions of tumor cells, including proliferation. The
Externí odkaz:
https://doaj.org/article/c1b2af0f6b76413797504c8fcda5dff0
Autor:
Oliver Richmond, Maryam Ghotbaddini, Cidney Allen, Alice Walker, Shokouh Zahir, Joann B Powell
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95058 (2014)
Distant prostate cancers are commonly hormone refractory and exhibit increased growth no longer inhibited by androgen deprivation therapy. Understanding all molecular mechanisms contributing to uncontrolled growth is important to obtain effective tre
Externí odkaz:
https://doaj.org/article/aa5edbd8461d420d9cbfb680eb34cccb
Autor:
Kofi K. Khamit-Kush, Joann B. Powell, Jeffrey A. Handy, Nathan J. Bowen, Valerie Odero-Marah, Daqing Wu
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:C023-C023
The aryl hydrocarbon receptor (AhR) is a nuclear transcription factor and xenobiotic sensor reported to mediate diet-induced obesity and is upregulated in high-grade prostate cancer (PCa). Previously published data from our lab shows AhR protein is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b23c62b669fe7b3a427cca500ad4c41
https://doi.org/10.1158/1538-7755.disp22-c023
https://doi.org/10.1158/1538-7755.disp22-c023
Autor:
Kofi Kyenku Khamit-Kush, Joann B. Powell, Jeffrey A. Handy, Nathan Bowen, Daqing Wu, Valerie Odero-Marah
Publikováno v:
Cancer Research. 82:394-394
The aryl hydrocarbon receptor (AhR) is a nuclear transcription factor and xenobiotic sensor reported to mediate diet-induced obesity and is upregulated in high-grade prostate cancer (PCa). Previously published data from our lab shows that AhR protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f9b333aa5d77f17d48cde07ec0615f
https://doi.org/10.1158/1538-7445.am2022-394
https://doi.org/10.1158/1538-7445.am2022-394
Publikováno v:
Journal of cancer treatment & diagnosis
Research on the aryl hydrocarbon receptor (AhR) has largely focused on its activation by various environmental toxins. Consequently, only limited inferences have been made regarding its constitutive activity in the absence of an exogenous ligands. Ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573897a9ae39f11a545b030471362626
http://europepmc.org/articles/PMC6641558
http://europepmc.org/articles/PMC6641558
Autor:
Maryam Ghotbaddini, Joann B. Powell
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 12, Iss 7, Pp 7506-7518 (2015)
International Journal of Environmental Research and Public Health
Volume 12
Issue 7
Pages 7506-7518
International Journal of Environmental Research and Public Health
Volume 12
Issue 7
Pages 7506-7518
The reported biological effects of TCDD include induction of drug metabolizing enzymes, wasting syndrome and tumor promotion. TCDD elicits most of its effects through binding the aryl hydrocarbon receptor (AhR). TCDD induced degradation of AhR has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5603aea458b6aab04ad466ee8a90511
http://www.mdpi.com/1660-4601/12/7/7506
http://www.mdpi.com/1660-4601/12/7/7506
Publikováno v:
Cancer Research. 79:2629-2629
The aryl hydrocarbon receptor (AhR) has been reported to interact with multiple signaling pathways during prostate cancer progression to castration resistant prostate cancer (CRPC) including the androgen receptor. Previously published data from our l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f9f93ed2e1aae20e9ba79609c7d1a10
https://doi.org/10.1158/1538-7445.am2019-2629
https://doi.org/10.1158/1538-7445.am2019-2629
Publikováno v:
Journal of cancer therapy
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates a battery of genes in response to exposure to a broad class of environmental poly aromatic hydrocarbons (PAH). AhR is historically characterized for its rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffeb2f5818bbac38078345c4a4fcd67b
https://doi.org/10.4236/jct.2013.47137
https://doi.org/10.4236/jct.2013.47137
Autor:
Joann B. Powell, Maryam Ghotbaddini
Publikováno v:
Biochemistry & pharmacology : open access
Polyaromatic hydrocarbons, heterocyclic aromatic amines and dioxin-like compounds are environmental carcinogens shown to initiate cancer in a number of tissue types including prostate and breast. These environmental carcinogens elicit their effects t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc616c68e868da88d9f3b99d325819b
https://pubmed.ncbi.nlm.nih.gov/25258701
https://pubmed.ncbi.nlm.nih.gov/25258701
Autor:
Maryam Ghotbaddini, Alice Walker, Oliver Richmond, Cidney J. Allen, Shokouh Taghipour Zahir, Joann B. Powell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e95058 (2014)
PLoS ONE, Vol 9, Iss 4, p e95058 (2014)
Background Distant prostate cancers are commonly hormone refractory and exhibit increased growth no longer inhibited by androgen deprivation therapy. Understanding all molecular mechanisms contributing to uncontrolled growth is important to obtain ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55df80b314fce7a5b634055d2f3f9421
http://europepmc.org/articles/PMC3995675
http://europepmc.org/articles/PMC3995675