Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Joann B, Sweasy"'
Autor:
Elizabeth Jose, Woody March-Steinman, Bryce A. Wilson, Lisa Shanks, Chance Parkinson, Isabel Alvarado-Cruz, Joann B. Sweasy, Andrew L. Paek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Oxidative stress from excess H2O2 activates transcription factors that restore redox balance and repair oxidative damage. Although many transcription factors are activated by H2O2, it is unclear whether they are activated at the same H2O2 co
Externí odkaz:
https://doaj.org/article/a98eff01ebe8481e85f36c4b70106900
Autor:
Rithy Meas, Joanne Nititham, Kimberly E. Taylor, Stephen Maher, Kaylyn Clairmont, Kelly E. W. Carufe, Michael Kashgarian, Timothy Nottoli, Ana Cheong, Zachary D. Nagel, Patrick M. Gaffney, Lindsey A. Criswell, Joann B. Sweasy
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 9, Pp 760-770 (2022)
Objective To determine if single‐nucleotide polymorphisms (SNPs) in DNA repair genes are enriched in individuals with systemic lupus erythematosus (SLE) and if they are sufficient to confer a disease phenotype in a mouse model. Methods Human exome
Externí odkaz:
https://doaj.org/article/97dbb8d80fed4e8691a4b02bf4ca46c8
Autor:
Tania Rahim, Madison A Levinson, Kelly E W Carufe, Matthew Burak, Rithy Meas, Stephen Maher, Alfred L M Bothwell, Naomi Gades, Joann B Sweasy
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267913 (2022)
Systemic lupus erythematosus is a chronic disease characterized by autoantibodies, renal and cutaneous disease, and immune complex formation. Emerging evidence suggests that aberrant DNA repair is an underlying mechanism of lupus development. We prev
Externí odkaz:
https://doaj.org/article/89a3a8278fd4466b8bc82a4e6f4224b0
Autor:
Joann B. Sweasy, Peter M. Glazer, Daniel Zelterman, Michelle DeVeaux, Elisa de Stanchina, Jane S. Merkel, Laura Abriola, Antonia A. Nemec
Resistance to cancer chemotherapies leads to deadly consequences, yet current research focuses only on the roles of somatically acquired mutations in this resistance. The mutational status of the germline is also likely to play a role in the way cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b0524d92c261c79717b95e79436efc
https://doi.org/10.1158/1541-7786.c.6539953.v1
https://doi.org/10.1158/1541-7786.c.6539953.v1
Autor:
Joann B. Sweasy, David P. Tuck, Joanne B. Weidhaas, Vincent Schulz, B. Frazier Taylor, Jamie B. Towle-Weicksel, Korie B. Bush, Antonia A. Nemec
Treatment with estrogen does not affect cellular proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421d38e4ec04fcea2b5942a0728ccd87
https://doi.org/10.1158/1541-7786.22514728.v1
https://doi.org/10.1158/1541-7786.22514728.v1
Autor:
Joann B. Sweasy, David P. Tuck, Joanne B. Weidhaas, Vincent Schulz, B. Frazier Taylor, Jamie B. Towle-Weicksel, Korie B. Bush, Antonia A. Nemec
Supporting Information Figure Legends from Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer–Associated R438W DNA Polymerase Lambda Protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be59880a6ab579fcf32c37c34426e38b
https://doi.org/10.1158/1541-7786.22514725.v1
https://doi.org/10.1158/1541-7786.22514725.v1
Autor:
Joann B. Sweasy, Peter M. Glazer, Daniel Zelterman, Michelle DeVeaux, Elisa de Stanchina, Jane S. Merkel, Laura Abriola, Antonia A. Nemec
S1. Dose-response curve of MCF7 cells. S2. Western blotting analysis of Pol beta in cell lines. S3. Pol beta and XPA interact in vitro. S4. The effect of E295K Pol beta expression on survival following cisplatin treatment. Table S1. Difference in via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2fa29c486bfc56559f504ef6aabbdc
https://doi.org/10.1158/1541-7786.22511491.v1
https://doi.org/10.1158/1541-7786.22511491.v1
Autor:
Danielle L. Sawyer, Joann B. Sweasy
Publikováno v:
Critical Reviews™ in Oncogenesis. 27:17-33
DNA polymerase beta (Pol β) is a 39 kD vertebrate polymerase that lacks proofreading ability, yet still maintains a moderate fidelity of DNA synthesis. Pol β is a key enzyme that functions in the base excision repair and non-homologous end joining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6236350e4317b0734237a852061ea57a
https://doi.org/10.1615/critrevoncog.2022043477
https://doi.org/10.1615/critrevoncog.2022043477
Autor:
ME Wood, KK Landry, Wendy McKinnon, DJ Seward, M Cuke, JA Dragon, SS Wallace, L Colello, K Xu, Joann B. Sweasy, M Slavik
Publikováno v:
Cancer Genetics. :30-36
Background: It is likely that additional genes for hereditary breast cancer can be identified using a discordant sib pair design. Using this design we identified individuals harboring a rare PMS1 c.605G>A variant previously predicted to result in los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84b0485bd965f231bf0a87cc8b160c5
https://doi.org/10.1016/j.cancergen.2021.11.004
https://doi.org/10.1016/j.cancergen.2021.11.004
Autor:
Joann B. Sweasy, Ivo Abraham, Brian L. Erstad, Daniel O. Persky, Ali McBride, Neda Alrawashdh
Publikováno v:
Annals of Hematology. 100:2501-2512
In this population-based study, we used the SEER database (1985–2015) to examine survival outcomes in chronic lymphocytic leukemia (CLL) patients followed up to the era of advanced treatments including targeted therapies. Data were extracted for pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02843a17d96a83f4c75460e2102df816
https://doi.org/10.1007/s00277-021-04600-1
https://doi.org/10.1007/s00277-021-04600-1