Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joanie Caroon"'
Autor:
Charles Alois Dvorak, Francisco Javier Lopez-Tapia, Xiaojun Huang, Brad Loe, Debra A. Cockayne, William L. Fitch, Scott Broadbent, Berger Jacob, Christine E. Brotherton-Pleiss, Keith A. M. Walker, Rebecca Suttmann, David L. Bourdet, Lee Edwin Lowrie, Shelley K. Gleason, Dov Nitzan, Paul J. Wagner, Jiang Zhu, Zhao Shu-Hai, Fernando Padilla, André Alker, Joanie Caroon, Deborah Phippard, Alam Jahangir, Pankaj D. Rege
Publikováno v:
Journal of medicinal chemistry. 58(21)
Identification of singleton P2X7 inhibitor 1 from HTS gave a pharmacophore that eventually turned into potential clinical candidates 17 and 19. During development, a number of issues were successfully addressed, such as metabolic stability, plasma st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e880f027ef8eadeaef6f8cc77b4f99c
https://pubmed.ncbi.nlm.nih.gov/26460788
https://pubmed.ncbi.nlm.nih.gov/26460788
Autor:
Francisco Lopez-Tapia, Keith A. M. Walker, Christine Brotherton-Pleiss, Joanie Caroon, Dov Nitzan, Lee Lowrie, Shelley Gleason, Shu-Hai Zhao, Jacob Berger, Debra Cockayne, Deborah Phippard, Rebecca Suttmann, William L. Fitch, David Bourdet, Pankaj Rege, Xiaojun Huang, Scott Broadbent, Charles Dvorak, Jiang Zhu, Paul Wagner
Publikováno v:
Journal of Medicinal Chemistry; Nov2015, Vol. 58 Issue 21, p8413-8426, 14p