Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joana T. Lima"'
Autor:
Joana T. Lima, Jorge G. Ferreira
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
Cellular behavior is continuously influenced by mechanical forces. These forces span the cytoskeleton and reach the nucleus, where they trigger mechanotransduction pathways that regulate downstream biochemical events. Therefore, the nucleus has emerg
Externí odkaz:
https://doaj.org/article/7958364dff7d47f7bedb23bc42c40d5c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In preparation for mitosis, cells undergo extensive reorganization of the cytoskeleton and nucleus, so that chromosomes can be efficiently segregated into two daughter cells. Coordination of these cytoskeletal and nuclear events occurs through bioche
Externí odkaz:
https://doaj.org/article/70d291eb3af14a688106d843058dab95
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2329
Cell division requires a dynamic reorganization of cytoskeletal and nuclear components. One essential step is the separation of centrosomes, which allows the assembly of a microtubule-based mitotic spindle. This has to be spatially and temporally coo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9306df55ceda8f800137a09f0e7ac2f
https://pubmed.ncbi.nlm.nih.gov/34085223
https://pubmed.ncbi.nlm.nih.gov/34085223
Publikováno v:
Methods in Molecular Biology ISBN: 9781071615379
Cell division requires a dynamic reorganization of cytoskeletal and nuclear components. One essential step is the separation of centrosomes, which allows the assembly of a microtubule-based mitotic spindle. This has to be spatially and temporally coo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ee3061565dc0c0f26117ab3ad459ac1
https://doi.org/10.1007/978-1-0716-1538-6_13
https://doi.org/10.1007/978-1-0716-1538-6_13
Publikováno v:
Journal of cell science. 133(24)
During the initial stages of mitosis, multiple mechanisms drive centrosome separation and positioning. How they are functionally coordinated to promote centrosome migration to opposite sides of the nucleus remains unclear. Imaging analysis software h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b982491aa7f6eda91d1ccb00765c4f7b
https://pubmed.ncbi.nlm.nih.gov/33199521
https://pubmed.ncbi.nlm.nih.gov/33199521
Autor:
Helder Maiato, Joana T. Lima, Claudia Guasch Boldú, Jorge G Ferreira, Carolina Lemos, António J. Pereira, Bernardo Orr, Marin Barisic, Girish Rajendraprasad, Luísa T. Ferreira
Publikováno v:
Journal of Cell Biology
The Journal of Cell Biology
Ferreira, L T, Orr, B, Rajendraprasad, G, Pereira, A J, Lemos, C, Lima, J T, Guasch Boldú, C, Ferreira, J G, Barisic, M & Maiato, H 2020, ' α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity ', The Journal of Cell Biology, vol. 219, no. 4, e201910064 . https://doi.org/10.1083/jcb.201910064
The Journal of Cell Biology
Ferreira, L T, Orr, B, Rajendraprasad, G, Pereira, A J, Lemos, C, Lima, J T, Guasch Boldú, C, Ferreira, J G, Barisic, M & Maiato, H 2020, ' α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity ', The Journal of Cell Biology, vol. 219, no. 4, e201910064 . https://doi.org/10.1083/jcb.201910064
Detyrosination is a frequent posttranslational modification of long-lived microtubules that inhibits microtubule depolymerase activity in vitro. Ferreira et al. combine manipulation of tubulin tyrosine ligase and carboxypeptidase (Vasohibins-SVBP) ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a48921e7a00433d45806d706987b3c
Autor:
António J. Pereira, Joana T. Lima, Bernardo Orr, Carolina Lemos, Girish Rajendraprasad, Helder Maiato, Luísa T. Ferreira, Claudia Guasch Boldú, Jorge G Ferreira, Marin Barisic
Incorrect kinetochore-microtubule attachments during mitosis can lead to chromosomal instability, a hallmark of human cancers. Mitotic error correction relies on the kinesin-13 MCAK, a microtubule depolymerase whose activity in vitro is suppressed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f9a877c91617c5d2ffb46a247f0f84
https://doi.org/10.1101/801977
https://doi.org/10.1101/801977