Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Joana Saraiva"'
Autor:
Cláudia Febra, Joana Saraiva, Fátima Vaz, João Macedo, Hamza Mohammad Al-Hroub, Mohammad Harb Semreen, Rui Maio, Vitor Gil, Nelson Soares, Deborah Penque
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Venous thromboembolism (VTE) is a leading cause of cardiovascular mortality. The diagnosis of acute VTE is based on complex imaging exams due to the lack of biomarkers. Recent multi-omics based research has contributed to the deve
Externí odkaz:
https://doaj.org/article/ae6b77b95e0646b9ba45e68dbada8a98
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1102 (2024)
Type 2 diabetes mellitus (T2DM) is a significant risk factor for stroke. Nevertheless, the evidence supporting stringent glycemic control to reduce macrovascular complications, particularly stroke, is not as clear as for microvascular complications.
Externí odkaz:
https://doaj.org/article/09f208d55dc34b4ea838243b56369a48
Autor:
Joana Saraiva Rodrigues, Andreia Faria-Pereira, Sérgio Póvoas Camões, Ana Sofia Serras, Vanessa Alexandra Morais, Jorge Lira Ruas, Joana Paiva Miranda
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionThe development of reliable hepatic in vitro models may provide insights into disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However, several of the existing models depend on using high concentrations of hep
Externí odkaz:
https://doaj.org/article/fb5b241afdc84d2bac8e7045c79b15f0
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 12, Iss 1, Pp 1-9 (2020)
Abstract Introduction Adult-onset autoimmune diabetes (AID) has two different phenotypes: classic type 1 diabetes mellitus (T1DM), with insulin requirement just after diagnosis, and latent autoimmune diabetes in adults (LADA). The purpose of this stu
Externí odkaz:
https://doaj.org/article/9f4c8d6724fd480f9855ec70b577038a
Autor:
Barbara Silva, Joana Saraiva Rodrigues, Joana Paiva Miranda, Ana Sofia Almeida, Carla Fernandes, Paula Guedes de Pinho, Fernando Remião
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 79 (2022)
Liver damage is a common issue associated with synthetic cathinones abuse. Indeed, human stem cell-derived hepatocyte-like cells (HLCs) have been used as alternative in vitro models for hepatotoxicity studies, due to their ability to maintain a stabl
Externí odkaz:
https://doaj.org/article/41f12ffd2dfb4342b8fa417fbb24600c
Autor:
Joana Saraiva Amaral, Carlos Miguel Marto, João Farias, Daniela Alves Pereira, Jorge Ermida, Álvaro Banaco, António Campos Felino, Francisco Caramelo, Sérgio Matos
Publikováno v:
Bioengineering, Vol 9, Iss 7, p 276 (2022)
Background: The extraction of impacted mandibular third molars is a frequent dental surgery, interfering with patients’ quality of life. Ultrasonic surgery is an alternative to osteotomy with conventional rotary instruments. This study compares pos
Externí odkaz:
https://doaj.org/article/c8eb30f150444d259557bbdf2d3d014d
Autor:
Bárbara Silva, Joana Saraiva Rodrigues, Ana Sofia Almeida, Ana Rita Lima, Carla Fernandes, Paula Guedes de Pinho, Joana Paiva Miranda, Fernando Remião
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 368 (2022)
Pentedrone and methylone can express stereoselectivity in toxicokinetic and toxicodynamic processes. Similarly, their chiral discrimination in metabolism, which was not yet evaluated, can result in different metabolic profiles and subsequent hepatoto
Externí odkaz:
https://doaj.org/article/7daef644803040dfa4dd31edb7a97fa8
Autor:
Patricia Mendes, Maria Fonseca, Inês Aguiar, Nuno Pangaio, Luísa Confraria, Otília Queirós, Joana Saraiva, Pedro Monteiro, João Guerra
Publikováno v:
Acta Médica Portuguesa, Vol 30, Iss 11, Pp 769-774 (2017)
Introduction: Most mental disorders have a chronic evolution and therefore a certain amount of psychiatric readmissions are inevitable. Several studies indicate that over 25% of child and adolescent inpatients were readmitted within one year of disch
Externí odkaz:
https://doaj.org/article/645933864d9f46d8a014d2fc20a6bc85
Autor:
Sérgio Azevedo, Joana Saraiva, Francisco Caramelo, Lúcia Fadiga, Luísa Barros, Carla Baptista, Miguel Melo, Leonor Gomes, Francisco Carrilho
Publikováno v:
Acta Médica Portuguesa, Vol 32, Iss 1 (2019)
Introdução: O uso da terapêutica com perfusão subcutânea contínua de insulina na diabetes mellitus tipo 1 é cada vez mais frequente devido aos seus efeitos benéficos no controlo glicémico e na flexibilidade do estilo de vida. Constituiu obje
Externí odkaz:
https://doaj.org/article/68d4853e7f5146778548cb4ef9cefb7c
Publikováno v:
Case Reports in Endocrinology, Vol 2019 (2019)
Systemic inflammatory response syndrome (SIRS) can be a rare manifestation of pheochromocytoma, since this adrenal tumor may produce cytokines and other hormones or neuropeptides besides catecholamines. We report the case of a 53-year-old female pati
Externí odkaz:
https://doaj.org/article/2dd58aab8fd741728766f7ccf12f3745