Zobrazeno 1 - 10
of 476
pro vyhledávání: '"Joana N"'
Autor:
Ana S. André, Joana N. R. Dias, Sandra Aguiar, Sara Nogueira, Pedro Bule, Joana Inês Carvalho, João P. M. António, Marco Cavaco, Vera Neves, Soraia Oliveira, Gonçalo Vicente, Belmira Carrapiço, Berta São Braz, Barbara Rütgen, Lurdes Gano, João D. G. Correia, Miguel Castanho, Joao Goncalves, Pedro M. P. Gois, Solange Gil, Luís Tavares, Frederico Aires-da-Silva
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Antibody–drug conjugates (ADCs) are among the fastest-growing classes of therapeutics in oncology. Although ADCs are in the spotlight, they still present significant engineering challenges. Therefore, there is an urgent need to develop mor
Externí odkaz:
https://doaj.org/article/f9c1a085d74e4cbdaf2217e2c95385f7
Autor:
Charles Agyemang, Bert-Jan H van den Born, Anke H Maitland-van der Zee, Albert G B Amoah, Kwesi Nyan Amissah-Arthur, Simone Hashimoto, Charles F Hayfron-Benjamin, Latif Musah, Benjamin Abaidoo, Pelagia Awula, Henry Wedoi Awuviri, Joseph Agyapong Abbey, Deladem A Fummey, Joana N Ackam, Gloria Odom Asante
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Objective Evidence shows that the conventional cardiometabolic risk factors do not fully explain the burden of microvascular complications in type 2 diabetes (T2D). One potential factor is the impact of pulmonary dysfunction on systemic microvascular
Externí odkaz:
https://doaj.org/article/9903d70e30254fabae1322cff667b552
Autor:
Ana S. André, Joana N. R. Dias, Sandra I. Aguiar, Ana Leonardo, Sara Nogueira, Joana D. Amaral, Célia Fernandes, Lurdes Gano, João D. G. Correia, Marco Cavaco, Vera Neves, Jorge Correia, Miguel Castanho, Cecília M. P. Rodrigues, Maria Manuela Gaspar, Luís Tavares, Frederico Aires-da-Silva
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionCancer is a major public health problem with over 19 million cases reported in 2020. Similarly to humans, dogs are also largely affected by cancer, with non-Hodgkin's lymphoma (NHL) among the most common cancers in both species. Comparati
Externí odkaz:
https://doaj.org/article/e1ae62f371ba4be582f085b5e995f720
Autor:
Joana N. R. Dias, André Almeida, Ana S. André, Sandra I. Aguiar, Pedro Bule, Sara Nogueira, Soraia S. Oliveira, Belmira Carrapiço, Solange Gil, Luís Tavares, Frederico Aires-da-Silva
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Anti-CD20 therapies have revolutionized the treatment of B-cell malignancies. Despite these advances, relapsed and refractory disease remains a major treatment challenge. The optimization of CD20-targeted immunotherapies is considered a prom
Externí odkaz:
https://doaj.org/article/ccec3d367937465e89f52aafc3853533
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody research and clinical development. However, limitations of the hybrido
Externí odkaz:
https://doaj.org/article/123a998e52ef41de80fa85bbf91ca29a
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 590-596 (2021)
Abstract Background Evidence regarding the efficacy of equine hyperimmune plasma to prevent pneumonia in foals caused by Rhodococcus equi is limited and conflicting. Hypothesis Opsonization with R. equi‐specific hyperimmune plasma (HIP) will signif
Externí odkaz:
https://doaj.org/article/75f67f1debf24733834eb2f6856ef17d
Autor:
Marina Parrondo, Paloma Morán, Marion Ballenghien, Jose L. Acuña, Alba Aguión, Julio Arrontes, Juliette Chiss, Teresa Cruz, Joana N. Fernandes, Lucía García-Flórez, Eva García-Vázquez, Katja J. Geiger, Gonzalo Macho, Eric Thiébaut, Nicolas Weidberg, Didier Jollivet, Yaisel J. Borrell
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
The stalked barnacle Pollicipes pollicipes inhabits rocky shores from the Atlantic coasts of Brittany (France) to Senegal. Because of the culinary traditions of southern Europe, stalked barnacles represent an important target species for local fisher
Externí odkaz:
https://doaj.org/article/b74aa92c03114d4684f39c6ace528bd2
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264292 (2022)
Chlamydia trachomatis causes genital and ocular infections in humans. This bacterial pathogen multiplies exclusively within host cells in a characteristic vacuole (inclusion) and delivers proteins such as inclusion membrane proteins (Incs) into the h
Externí odkaz:
https://doaj.org/article/31495d6a5cf047db9c831d2d20488ee3
Autor:
Joana N. R. Dias, Ana S. André, Sandra I. Aguiar, Solange Gil, Luís Tavares, Frederico Aires-da-Silva
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
The new era of immune-oncology has brought complexities and challenges that emphasize the need to identify new strategies and models to develop successful and cost-effective therapies. The inclusion of a canine model in the drug development of cancer
Externí odkaz:
https://doaj.org/article/b91f2964e9dd42668c690e937047549a
Autor:
Joana N. Bugalhão, Luís Jaime Mota
Publikováno v:
Microbial Cell, Vol 6, Iss 9, Pp 414-449 (2019)
Chlamydia trachomatis serovars are obligate intracellular bacterial pathogens mainly causing ocular and urogenital infections that affect millions of people worldwide and which can lead to blindness or sterility. They reside and multiply intracellula
Externí odkaz:
https://doaj.org/article/2d2a90cfa9cc444ca086aac92a9947c5