Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joana Moitinho Oliveira"'
Autor:
Romina Bertinat, Francisco Westermeier, Pamela Silva, Rodrigo Gatica, Joana Moitinho Oliveira, Francisco Nualart, Ramón Gomis, Alejandro J. Yáñez
Publikováno v:
Journal of Diabetes Research, Vol 2018 (2018)
The kidney is an insulin-sensitive organ involved in glucose homeostasis. One major effect of insulin is to induce glycogen storage in the liver and muscle. However, no significant glycogen stores are detected in normal kidneys, but diabetic subjects
Externí odkaz:
https://doaj.org/article/f8e22832fd6743aab1817b35f903dc64
Publikováno v:
Medicina Reproductiva y Embriología Clínica. 3:152-158
Resumen La supresion del gen del sustrato 2 del receptor de insulina (IRS-2) induce una alteracion del eje hipotalamo-ovarico como consecuencia de la induccion de resistencia central a leptina. Las hembras IRS-2−/− se caracterizan por una anovula
Autor:
Rodrigo Gatica, Romina Bertinat, Francisco Nualart, Alejandro J. Yáñez, Francisco Westermeier, Pamela Silva, Ramon Gomis, Joana Moitinho Oliveira
Publikováno v:
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2018 (2018)
Journal of Diabetes Research, Vol 2018 (2018)
The kidney is an insulin-sensitive organ involved in glucose homeostasis. One major effect of insulin is to induce glycogen storage in the liver and muscle. However, no significant glycogen stores are detected in normal kidneys, but diabetic subjects
Autor:
Ainhoa Garcia, Sandra A. Rebuffat, Delia Zafra, Deborah J. Burks, Rosa Gasa, Susana G. Kalko, Joana Moitinho Oliveira, Joan J. Guinovart, Ramon Gomis
Publikováno v:
AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, American Physiological Society, 2014, 306 (1), pp.E36-E47. ⟨10.1152/ajpendo.00409.2013⟩
AJP-Endocrinology and Metabolism, American Physiological Society, 2014, 306 (1), pp.E36-E47. ⟨10.1152/ajpendo.00409.2013⟩
Pancreatic β-cells play a central role in type 2 diabetes (T2D) development, which is characterized by the progressive decline of the functional β-cell mass that is associated mainly with increased β-cell apoptosis. Thus, understanding how to enha
Autor:
Jordi Altirriba, Sandra A. Rebuffat, Yaiza Esteban, Nuria Palau, Joana Moitinho Oliveira, Ainhoa Garcia, Belen Nadal, Ramon Gomis
Publikováno v:
Diabetologia. 56:2446-2455
During obesity, the increment in beta cell mass in response to the rising demand for insulin is essential to maintain normal glucose homeostasis. However, the precise cellular and molecular mechanisms involved in beta cell mass plasticity remain poor
Autor:
Marina Casimir, Mariana Igoillo-Esteve, Fabio Arturo Grieco, Joana Moitinho Oliveira, Marco Bugliani, Feyza Engin, Flora Brozzi, Tarlliza R. Nardelli, Olatz Villate, Piero Marchetti, Jenny Barthson, Isabelle Millard, Gökhan S. Hotamisligil, Decio L. Eizirik, Miguel Lopes
Publikováno v:
Diabetologia. 58(10)
Proinflammatory cytokines contribute to beta cell damage in type 1 diabetes in part through activation of endoplasmic reticulum (ER) stress. In rat beta cells, cytokine-induced ER stress involves NO production and consequent inhibition of the ER Ca(2
Publikováno v:
Canadian Journal of Physiology and Pharmacology
Canadian Journal of Physiology and Pharmacology, NRC Research Press, 2014, 92 (8), pp.613-620. ⟨10.1139/cjpp-2014-0114⟩
Canadian Journal of Physiology and Pharmacology, NRC Research Press, 2014, 92 (8), pp.613-620. ⟨10.1139/cjpp-2014-0114⟩
Insulin receptor substrate 2 (IRS2) is a widely expressed protein that regulates crucial biological processes including glucose metabolism, protein synthesis, and cell survival. IRS2 is part of the insulin – insulin-like growth factor (IGF) signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7941f45ee058d23cdd4ea517ff7f43e
https://hal.umontpellier.fr/hal-02103070
https://hal.umontpellier.fr/hal-02103070