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Akademický článek

The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

Publikováno v: eLife, Vol 13 (2024)

Male germ cells share a common origin across animal species, therefore they likely retain a conserved genetic program that defines their cellular identity. However, the unique evolutionary dynamics of male germ cells coupled with their widespread lea

Externí odkaz: https://doaj.org/article/2abf73b38c2f4697a2904a171653c40a

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Akademický článek

Decontamination of genetically modified mice strains by embryo transfer for obtaining SPF colonies in a Brazilian animal facility

Autor: Ana Tada Fonseca Brasil Antiorio, Sílvia Maria Gomes Massironi, Rosália Regina de Luca, Márcio Augusto Caldas Rocha Carvalho, Vanessa Yamamoto Tambellini, Danilo Wadt, Juliana Bortolatto, Joana Bom, Claudia Madalena Cabrera Mori

Publikováno v: Brazilian Journal of Veterinary Research and Animal Science, Vol 56, Iss 1 (2019)

The introduction of new strains of mice in specific pathogen-free (SPF) animal facilities should be performed carefully to avoid breaking sanitary barriers. To meet this need, animals should be rederived to reduce infection risk and thus avoid resear

Externí odkaz: https://doaj.org/article/e26460da3b3948cbab6865c7f56c2100

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Akademický článek

Microbiota Alters Urinary Bladder Weight and Gene Expression

Autor: Blanka Roje, Anamaria Elek, Vinko Palada, Joana Bom, Aida Iljazović, Ana Šimić, Lana Sušak, Katarina Vilović, Till Strowig, Kristian Vlahoviček, Janoš Terzić

Publikováno v: Microorganisms, Vol 8, Iss 3, p 421 (2020)

We studied the effect of microbiota on the transcriptome and weight of the urinary bladder by comparing germ-free (GF) and specific pathogen-free (SPF) housed mice. In total, 97 genes were differently expressed (fold change > ±2; false discovery rat

Externí odkaz: https://doaj.org/article/127138308b794ebf887bb9180e63c0f1

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Microbiota Alters Urinary Bladder Weight and Gene Expression

Autor: Till Strowig, Blanka Roje, Vinko Palada, Ana Šimić, Joana Bom, Katarina Vilović, Lana Sušak, Anamaria Elek, Aida Iljazovic, Kristian Vlahoviček, Janoš Terzić

Publikováno v: Microorganisms
Volume 8
Issue 3
Switzerland
Microorganisms, Vol 8, Iss 3, p 421 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b241e30a4cc69d467fcf44f88b1f1e48

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Decontamination of genetically modified mice strains by embryo transfer for obtaining SPF colonies in a Brazilian animal facility

Autor: Joana Bom, Vanessa Yamamoto Tambellini, Ana Tada Fonseca Brasil Antiorio, Márcio Augusto Caldas Rocha Carvalho, Claudia Madalena Cabrera Mori, Rosália Regina de Luca, Juliana Bortolatto, Danilo Wadt, Silvia Maria Gomes Massironi

Publikováno v: Brazilian Journal of Veterinary Research and Animal Science, Vol 56, Iss 1 (2019)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29896c48a5ac6b406f819e094f811204
http://www.revistas.usp.br/bjvras/article/view/143588

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Amidomethylation of amodiaquine: antimalarial N-Mannich base derivatives

Autor: Catarina M. Casimiro, Rui Moreira, Jose O. Goncaves, Jim Iley, Francisca Lopes, Peter N. Horton, Joana Bom, Michael B. Hursthouse, Rita Capela

Publikováno v: Tetrahedron Letters. 45:7663-7666

Novel N-Mannich base-type derivatives of the antimalarial drug amodiaquine were synthesised by reaction with tertiary N-chloromethylamides. With the exception of the derivative of ethyl hippurate, all the so-formed (1-amidomethyl-1H-quinolin-4-yliden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5de565b77906e9834af9270f763b72
https://doi.org/10.1016/j.tetlet.2004.08.093

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Regulatory role for a conserved motif adjacent to the homeodomain of Hox10 proteins

Autor: Moisés Mallo, Isabel Guerreiro, Joana Bom, Ana Casaca, Ana Nóvoa, Ricardo B. Ferreira, Andreia Nunes, Sara Monteiro

Publikováno v: Development (Cambridge, England). 139(15)

Development of the vertebrate axial skeleton requires the concerted activity of several Hox genes. Among them, Hox genes belonging to the paralog group 10 are essential for the formation of the lumbar region of the vertebral column, owing to their ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7900f2848be7e40d075c89ba85c844
https://pubmed.ncbi.nlm.nih.gov/22721778

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Evidence for a Myotomal Hox/Myf Cascade Governing Nonautonomous Control of Rib Specification within Global Vertebral Domains

Autor: Tânia Vinagre, Marta Carapuço, Joana Bom, Natalia Moncaut, Moisés Mallo, Ana Nóvoa

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Hox genes are essential for the patterning of the axial skeleton. Hox group 10 has been shown to specify the lumbar domain by setting a rib-inhibiting program in the presomitic mesoderm (PSM). We have now produced mice with ribs in every vertebra by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e251e9144017bf0db3085d2023bfcd0

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The interest of mitochondrial DNA coding region SNPS

Autor: Joana Bom, Paulo Dario, Teresa Ribeiro, Helena Geada, A. Sucena

Res_eng:As analysis of mtDNA hypervariable regions is a laborious technique, it is desirable to type mtSN Ps before performing sequencing. This study presents a 10 SN P multiplex, selected from mitochondrial coding region loci. These markers can subd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02987a7ec103f74de451cef087de602d
https://doi.org/10.14195/978-989-26-0173-1_14

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