Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Joana Bicker"'
Autor:
Jordi Olloquequi, Miren Ettcheto, Amanda Cano, Ana Fortuna, Joana Bicker, Elena Sánchez-Lopez, Cristian Paz, Jesús Ureña, Ester Verdaguer, Carme Auladell, Antoni Camins
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14177 (2023)
Licochalcone A (Lico-A) is a flavonoid compound derived from the root of the Glycyrrhiza species, a plant commonly used in traditional Chinese medicine. While the Glycyrrhiza species has shown promise in treating various diseases such as cancer, obes
Externí odkaz:
https://doaj.org/article/a794e4b48b1040d6a767bea4fdecd380
Autor:
Rui Silva, Helena Colom, Joana Bicker, Anabela Almeida, Ana Silva, Francisco Sales, Isabel Santana, Amílcar Falcão, Ana Fortuna
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1704 (2023)
Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of
Externí odkaz:
https://doaj.org/article/1a499d849c894123a713d50ccc2d2018
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 373 (2023)
Amikacin is the antibiotic of choice for the treatment of Gram-negative infections, namely, those in neutropenic oncology patients. No populational pharmacokinetic studies are currently available reporting amikacin pharmacokinetics in neutropenic onc
Externí odkaz:
https://doaj.org/article/9456b2adce564e09811156e7448e90ae
Autor:
Soraia Silva, Joana Bicker, Carla Fonseca, Nuno R. Ferreira, Carla Vitorino, Gilberto Alves, Amílcar Falcão, Ana Fortuna
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Depression is a common mental disorder. Its treatment with selective serotonin reuptake inhibitors (SSRIs) is effective only in a fraction of patients, and pharmacoresistance is increasing steadily. Intranasal (IN) drug delivery to the brain stands o
Externí odkaz:
https://doaj.org/article/c555d32d8b50493e9adac2c1c0e8ed7d
Autor:
Rui Silva, Joana Bicker, Anabela Almeida, Andreia Carona, Ana Silva, Francisco Sales, Isabel Santana, Amílcar Falcão, Ana Fortuna
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2127 (2022)
Adherence to antiseizure drug treatment determines its effectiveness and safety, and consequently affects patients’ quality of life. Herein, we assessed adherence to levetiracetam in Portuguese patients with refractory epilepsy (n = 115), with reso
Externí odkaz:
https://doaj.org/article/3eed93f3631e429c960ea486a33eca76
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1975 (2021)
Scientific evidence that circadian rhythms affect pharmacokinetics and pharmacodynamics has highlighted the importance of drug dosing-time. Circadian oscillations alter drug absorption, distribution, metabolism, and excretion (ADME) as well as intrac
Externí odkaz:
https://doaj.org/article/04f3a6f7dd684a28a2b65435b4c88349
Autor:
Rui Silva, Anabela Almeida, Joana Bicker, Joana Gonçalves, Andreia Carona, Ana Silva, Isabel Santana, Francisco Sales, Amílcar Falcão, Ana Fortuna
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 943 (2020)
Levetiracetam is a second-generation antiepileptic drug, widely used in the treatment of focal and generalized epilepsy due to its pharmacokinetic and safety profiles. Its pharmacokinetic monitoring is ascribed as useful to personalize its dosing reg
Externí odkaz:
https://doaj.org/article/30dc84a2120941b8b79a15ed43c7ea20
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 184:62-82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea40ce75d92cc84efa96277054e1da1
https://doi.org/10.1016/j.ejpb.2023.01.013
https://doi.org/10.1016/j.ejpb.2023.01.013
Autor:
Fortuna, Rui Silva, Helena Colom, Joana Bicker, Anabela Almeida, Ana Silva, Francisco Sales, Isabel Santana, Amílcar Falcão, Ana
Publikováno v:
Pharmaceutics; Volume 15; Issue 6; Pages: 1704
Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::b5ab3421d78696c0df0cc54ba7949f01
Publikováno v:
Current Pharmaceutical Design. 26:594-619
Background:Several natural compounds have demonstrated potential for the treatment of central nervous system disorders such as ischemic cerebrovascular disease, glioblastoma, neuropathic pain, neurodegenerative diseases, multiple sclerosis and migrai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e51d7beee7893d58fe41c152aa6dd6
https://doi.org/10.2174/1381612826666200115101544
https://doi.org/10.2174/1381612826666200115101544