Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Joana Barbosa Melo"'
Autor:
Patrícia Barreto, Cláudia Farinha, Rita Coimbra, Maria Luz Cachulo, Joana Barbosa Melo, Yara Lechanteur, Carel B. Hoyng, José Cunha-Vaz, Rufino Silva
Publikováno v:
Eye and Vision, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Background Age-related macular degeneration (AMD) is a multifactorial degenerative disease of the macula. Different factors, environmental, genetic and lifestyle, contribute to its onset and progression. However, how they interconnect to pro
Externí odkaz:
https://doaj.org/article/8ff3be4bc9c94e22a57e4cffffce8959
Autor:
Joana Jesus-Ribeiro, Olinda Rebelo, Conceição Bento, Cristina Pereira, Conceição Robalo, Manuel Rito, Ricardo Pereira, José Augusto Costa, Joana Barbosa Melo, António Freire, Isabel Santana, Francisco Sales
Publikováno v:
Acta Médica Portuguesa, Vol 35, Iss 13 (2022)
Introduction: Over recent decades, brain resection for drug-resistant epilepsy has proven to be a valuable treatment option. The histopathological classification was of paramount value for patient management. The aims of this study were to characteri
Externí odkaz:
https://doaj.org/article/5b34325f329a4ebb84b384fdd035f245
Autor:
Raquel Alves, Diogo Santos, Joana Jorge, Ana Cristina Gonçalves, Steve Catarino, Henrique Girão, Joana Barbosa Melo, Ana Bela Sarmento-Ribeiro
Publikováno v:
Molecules, Vol 28, Iss 3, p 1210 (2023)
Heat shock protein 90 (HSP90) facilitates folding and stability and prevents the degradation of multiple client proteins. One of these HSP90 clients is BCR-ABL, the oncoprotein characteristic of chronic myeloid leukemia (CML) and the target of tyrosi
Externí odkaz:
https://doaj.org/article/6e301b37396c4c7fa18ed9fb6e3a1237
Autor:
Ilda Patrícia Ribeiro, Luísa Esteves, Francisco Caramelo, Isabel Marques Carreira, Joana Barbosa Melo
Publikováno v:
Cells, Vol 11, Iss 16, p 2536 (2022)
Head and Neck Cancer (HNC) is characterized by phenotypic, biological, and clinical heterogeneity. Despite treatment modalities, approximately half of all patients will die of the disease. Several molecular biomarkers have been investigated, but unti
Externí odkaz:
https://doaj.org/article/2fa6a6dbd4e3478bb78a21257e5330e3
Autor:
Joana Jesus-Ribeiro, Luís Miguel Pires, João Daniel Melo, Ilda Patrícia Ribeiro, Olinda Rebelo, Francisco Sales, António Freire, Joana Barbosa Melo
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Introduction: Focal cortical dysplasias (FCDs) are a group of malformations of cortical development that constitute a common cause of drug-resistant epilepsy, often subjected to neurosurgery, with a suboptimal long-term outcome. The past few years ha
Externí odkaz:
https://doaj.org/article/05176c81bd0544a8ac61fc3e129b8836
Autor:
Selin Pars, Fernando Cristo, José M. Inácio, Graça Rosas, Isabel Marques Carreira, Joana Barbosa Melo, Patrícia Mendes, Duarte Saraiva Martins, Luís Pereira de Almeida, José Maio, Rui Anjos, José A. Belo
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 202-206 (2018)
A DAND5-control human iPSC line was generated from the urinary cells of a phenotypically normal donor. Exfoliated renal epithelial (RE) cells were collected and reprogrammed into iPSCs using Sendai virus reprogramming system. The pluripotency, in vit
Externí odkaz:
https://doaj.org/article/d4165075489f4a8cbd30edac48fd963a
Autor:
Fernando Cristo, José M. Inácio, Graça Rosas, Isabel Marques Carreira, Joana Barbosa Melo, Luís Pereira de Almeida, Patrícia Mendes, Duarte Saraiva Martins, José Maio, Rui Anjos, José A. Belo
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 152-156 (2017)
A human iPSC line was generated from exfoliated renal epithelial (ERE) cells of a patient affected with Congenital Heart Disease (CHD) and Laterality Defects carrying tshe variant p.R152H in the DAND5 gene. The transgene-free iPSCs were generated wit
Externí odkaz:
https://doaj.org/article/225a04f8ed24453ebb2bf1247699c20d
Autor:
Joana Barbosa Melo
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 37, Iss 9, Pp 737-738 (2018)
Externí odkaz:
https://doaj.org/article/92342ee7ef1a4b2ab88490a4fadaae78
Autor:
Joana Jesus‐Ribeiro, Olinda Rebelo, Ilda Patrícia Ribeiro, Luís Miguel Pires, João Daniel Melo, Francisco Sales, Isabel Santana, António Freire, Joana Barbosa Melo
Publikováno v:
Neuropathology. 42:467-482
Low-grade neuroepithelial tumors (LNETs) represent an important group of central nervous system neoplasms, some of which may be associated to epilepsy. The concept of long-term epilepsy-associated tumors (LEATs) includes a heterogenous group of low-g
Autor:
Joana Jesus-Ribeiro, Ilda Patrícia Ribeiro, Luís Miguel Pires, Patrícia Paiva, Sandra Simões, Cristina Pereira, Conceição Robalo, Ricardo Pereira, Francisco Sales, Olinda Rebelo, Isabel Santana, António Freire, Joana Barbosa Melo
Publikováno v:
Cytogenetic and Genome Research. 162:28-33
A palette of copy number changes in long-term epilepsy-associated tumors (LEATs) have been reported, but the data are heterogeneous. To better understand the molecular basis underlying the development of LEATs, we performed array-comparative genomic