Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joana B. Nunes"'
Autor:
Mafalda Santos, Marta Ferreira, Patrícia Oliveira, Nuno Mendes, Ana André, André F. Vieira, Joana B. Nunes, Joana Carvalho, Sara Rocha, Mafalda Azevedo, Daniel Ferreira, Inês Reis, João Vinagre, Joana Paredes, Alireza Heravi-Moussavi, Jorge Lima, Valdemar Máximo, Angela Burleigh, Calvin Roskelley, Fátima Carneiro, David Huntsman, Carla Oliveira
Publikováno v:
Biology, Vol 11, Iss 7, p 1046 (2022)
Transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression. We hypothesize that EMT followed by MET promotes cell population heterogeneity, favouring tumour growth. We developed an EMT model by on and of
Externí odkaz:
https://doaj.org/article/7302372388394956b9b27c7225a965ca
Autor:
Helena Pópulo, Sandra Tavares, Alexandra Faustino, Joana B. Nunes, José Manuel Lopes, Paula Soares
Publikováno v:
PeerJ, Vol 1, p e104 (2013)
Somatic mutations in GNAQ gene were described as being the main oncogenic activation in uveal melanomas, whereas mutations in BRAF gene have been described as a key genetic alteration that contributes to skin melanoma development. We have previously
Externí odkaz:
https://doaj.org/article/d5da14327fa44e96b654aaf38428c356
Autor:
Marta Ferreira, Mafalda Azevedo, David G. Huntsman, Joana Carvalho, Angela Burleigh, Alireza Heravi-Moussavi, Joana B. Nunes, Patrícia Oliveira, Daniel Ferreira, Ana André, Joana Paredes, André Filipe Vieira, Inês Leal Reis, Maria de Fátima Carneiro, Valdemar Máximo, João Vinagre, Sara Rocha, Mafalda Santos, Carla Oliveira, Nuno Mendes, Jorge Lima, Calvin D. Roskelley
Publikováno v:
Biology; Volume 11; Issue 7; Pages: 1046
Transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression. We hypothesize that EMT followed by MET promotes cell population heterogeneity favouring tumour growth. We developed an EMT model by on/off exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de34328f3b592e90d41e20644d372533
https://doi.org/10.1101/2021.11.02.466914
https://doi.org/10.1101/2021.11.02.466914
Publikováno v:
Journal of Adolescent Health. 65:558-563
Purpose Early timing of pubertal development is associated with worse cardiometabolic health in adulthood. We aimed to evaluate this association in 10-year-old girls and boys and clarify if it is independent of previous body mass index (BMI). Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bd227093ce88996d7567a43f984787
https://doi.org/10.1016/j.jadohealth.2019.05.014
https://doi.org/10.1016/j.jadohealth.2019.05.014
Autor:
Silvana Miranda, Paula Boaventura, Marcelo Correia, Valdemar Máximo, Paula Soares, Ana Pestana, Jorge Lima, Anabela G. Dias, Joana B. Nunes
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Radiobiology is moving towards a better understanding of the intercellular signaling that occurs upon radiation and how its effects relate to the dose applied. The mitochondrial role in orchestrating this biological response needs to be further explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e8b4746d968130829608d8c0d179fd
https://hdl.handle.net/10216/142511
https://hdl.handle.net/10216/142511
Autor:
Joana B. Nunes, Bart Everts
Publikováno v:
TRENDS IN CANCER, 5(11), 656-658. CELL PRESS
There is major interest in understanding the role of the tumor microenvironment in immune escape. In a recent report, Marijt et al. shed light on the signaling cascade that leads to decreased surface expression of MHC class I by tumor cells triggered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb566d6654f58ccaa40cb08638626bbc
https://hdl.handle.net/1887/122198
https://hdl.handle.net/1887/122198
Publikováno v:
Revue d'Épidémiologie et de Santé Publique. 66:S275-S276
Introduction There is increasing evidence that the timing of pubertal development is associated with adult adiposity and cardio-metabolic health. In regard to the effect of early timing of pubertal development on worse cardio-metabolic health, some a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6887358bb9a5f5a0179c2207ba61fae0
https://doi.org/10.1016/j.respe.2018.05.101
https://doi.org/10.1016/j.respe.2018.05.101
Autor:
Joana Peixoto, Valdemar Máximo, Maria Gomez-Lazaro, Keshav K. Singh, Salomé S. Pinho, André Filipe Vieira, Jorge Lima, Manuel Sobrinho-Simões, Paula Soares, Ildete L. Ferreira, Joana B. Nunes, Sandra Carvalho, Ana Cristina Rego, Joana Paredes
Publikováno v:
Human molecular genetics. 24(7)
Mitochondria are central organelles for cellular metabolism. In cancer cells, mitochondrial oxidative phosphorylation (OXPHOS) dysfunction has been shown to promote migration, invasion, metastization and apoptosis resistance. With the purpose of anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f1995fe08e175cf9897c52c5eadedf
https://pubmed.ncbi.nlm.nih.gov/25504047
https://pubmed.ncbi.nlm.nih.gov/25504047
Autor:
Ines Reis, André Filipe Vieira, Daniel Ferreira, Joana Carvalho, Joana B. Nunes, Alireza Heravi-Moussavi, Joana Paredes, João Vinagre, David G. Huntsman, Mafalda Azevedo, Valdemar Máximo, Angela Burleigh, Patrícia Oliveira, Carla Oliveira, Jorge Lima, Sara Rocha, Fátima Carneiro, Nuno Mendes, Calvin D. Roskelley
Publikováno v:
Cancer Research. 76:1611-1611
Reversible and dynamic transitions between epithelial and mesenchymal cellular states (EMT/MET) contribute to cancer progression and dissemination. Whereas EMT facilitates initial steps of tumour cell detachment, MET is likely required for colonizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8aeeb6f6812afed694aeb93fcd7a09d
https://doi.org/10.1158/1538-7445.am2016-1611
https://doi.org/10.1158/1538-7445.am2016-1611
Autor:
Ana P. Gomes, Didem Ilter, Vivien Low, Stanislav Drapela, Tanya Schild, Edouard Mullarky, Julie Han, Ilaria Elia, Dorien Broekaert, Adam Rosenzweig, Michal Nagiec, Joana B. Nunes, Bethany E. Schaffer, Anders P. Mutvei, John M. Asara, Lewis C. Cantley, Sarah-Maria Fendt, John Blenis
Publikováno v:
Nature Metabolism
The alteration of metabolic pathways is a critical strategy for cancer cells to attain the traits necessary for metastasis in disease progression. Here, we find that dysregulation of propionate metabolism produces a pro-aggressive signature in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca50deea4fba67584316f0dab70da5c