Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Joana A Palha"'
Autor:
Vitor Hugo Pereira, Patrício Soares Costa, Nadine Correia Santos, Pedro Guimarães Cunha, Margarida Correia-Neves, Joana A Palha, Nuno Sousa
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Background: Adult height, weight and adiposity measures have been suggested by some studies to be predictors of depression, cognitive impairment and dementia. However, the presence of confounding factors and the lack of a thorough neuropsychological
Externí odkaz:
https://doaj.org/article/6bcc7b0f1edb4586b540d89d44fc3ed3
Autor:
Daniela de Sá Calçada, Susana eRoque, Carlos eBranco, Susana eMonteiro, Bruno eCerqueira-Rodrigues, Nuno eSousa, Joana A Palha, Margarida eCorreia-Neves
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 9 (2015)
Depression is an extremely heterogeneous disorder. Diverse molecular mechanisms have been suggested to underlie its etiology. To understand the molecular mechanisms responsible for this complex disorder, researchers have been using animal models exte
Externí odkaz:
https://doaj.org/article/300ee73f8900491c86ab52a3674fca1c
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Maternal separation (MS), an early life stressful event, has been demonstrated to trigger neuropsychiatric disorders later in life, in particular depression. Experiments using rodents subjected to MS protocols have been very informative for the estab
Externí odkaz:
https://doaj.org/article/39cf52c01d28416b8f0684122d3374bd
Autor:
Shilan eAslani, Mazen R Harb, Patrício Soares Costa, Osborne FX Almeida, Nuno eSousa, Joana A Palha
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Chronic mild stress (CMS) protocols are widely used to create animal models of depression. Despite this, the inconsistencies in the reported effects may be indicative of crucial differences in methodology. Here, we considered the time of the diurnal
Externí odkaz:
https://doaj.org/article/da652e5ed4784c309f078d8d77ef4731
Autor:
Jose Miguel Soares, Adriana eSampaio, Paulo eMarques, Luis Miguel Ferreira, Nadine Correia Santos, Fernanda eMarques, Joana A Palha, João J Cerqueira, Nuno eSousa
Publikováno v:
Frontiers in Human Neuroscience, Vol 7 (2013)
Chronic stress has been widely reported to have deleterious impact in multiple biological systems. Specifically, structural and functional remodelling of several brain regions following prolonged stress exposure have been described; importantly, some
Externí odkaz:
https://doaj.org/article/92653b9256cb4efb8544795079c6be46
Autor:
Ashley eNovais, Ana Catarina Ferreira, Fernanda eMarques, José M Pêgo, João J Cerqueira, Ana eDavid-Pereira, Filipa L Campos, Christina eDalla, Nikolaos eKokras, Nuno eSousa, Joana A Palha, Joao C Sousa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
Neudesin (also known as neuron derived neurotrophic factor, Nenf) is a scarcely studied putative non-canonical neurotrophic factor. In order to understand its function in the brain, we performed an extensive behavioral characterization (motor, emotio
Externí odkaz:
https://doaj.org/article/0002fe366a034b37a397e32592327ec6
Autor:
Ana C Ferreira, Vitor ePinto, Sandro D Mesquita, Ashley eNovais, Joao C Sousa, Margarida eCorreia-Neves, Nuno eSousa, Joana A Palha, Fernanda eMarques
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
Lipocalin-2 (LCN2), an iron-related protein well described to participate in the innate immune response, has been shown to modulate spine morphology and to regulate neuronal excitability. In accordance, LCN2-null mice are reported to have stress-indu
Externí odkaz:
https://doaj.org/article/9917a84f4a184ce8944447a30bd163bc
Autor:
Ana Mendanha Falcao, Fernanda eMarques, Ashley eNovais, Nuno eSousa, Joana A Palha, Joao C Sousa
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 6 (2012)
In adult mammals, under physiological conditions, neurogenesis, the process of generating new functional neurons from precursor cells, occurs mainly in two brain areas: the subgranular zone in the dentate gyrus of the hippocampus, and the subventricu
Externí odkaz:
https://doaj.org/article/56b02fb994694f3a8bb8afb361525c8c
Autor:
Fernanda eMarques, Sandro D Mesquita, Joao C Sousa, Giovanni eCoppola, Fuying eGao, Daniel H Geschwind, Sandra eColumba-cabezas, Francesca eAloisi, Matilda eDegna, João J Cerqueira, Nuno eSousa, Margarida eCorreia-Neves, Joana A Palha
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 6 (2012)
Multiple sclerosis is a demyelinating disease that causes major neurological disability in young adults. A definitive diagnosis at the time of the first episode is still lacking, but since early treatment leads to better prognosis, the search for ear
Externí odkaz:
https://doaj.org/article/d29dcf13918b42d285cac08b4306a20c
Do genes and environment meet to regulate cerebrospinal fluid dynamics? Relevance for schizophrenia.
Autor:
Joana A Palha, Nadine C Santos, Fernanda eMarques, Joao C Sousa, João M Bessa, Rui eMiguelote, Nuno eSousa, Paulo eBelmonte de Abreu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 6 (2012)
Schizophrenia is a neurodevelopment disorder in which the interplay of genes and environment contributes to disease onset and establishment. The most consistent pathological feature in schizophrenic patients is an enlargement of the brain ventricles.
Externí odkaz:
https://doaj.org/article/786217d504b946beac43aef7990618cf