Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Joan-Carles Fernàndez"'
Autor:
Montserrat Miralpeix, Isabel Ramis, Peter Eichhorn, Joan-Carles Fernàndez, Raquel Otal, Anna Domènech, Jorge De Alba, M. I. Maldonado, Bernat Vidal, Neus Prats, Cristina Carreño, Adelina Orellana
Publikováno v:
Pharmacological Research. 99:116-124
Spleen tyrosine kinase (Syk) is essential for signal transduction of immunoreceptors. Inhibition of Syk abrogates mast cell degranulation and B cell responses. We hypothesized that Syk inhibition in the lung by inhaled route could block airway mast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e607a0023af33ae2bf56fede51a16192
https://doi.org/10.1016/j.phrs.2015.05.011
https://doi.org/10.1016/j.phrs.2015.05.011
Autor:
Joan-Carles Fernàndez, Patricia Niño, Marta Caba, Emma Terricabras, Nuria Aguilar, Fernando Albericio
Publikováno v:
ChemInform. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d46be7b986b221c02c1a1db66cca2f0e
https://doi.org/10.1002/chin.201652319
https://doi.org/10.1002/chin.201652319
Autor:
Joan-Carles Fernàndez, Natalia de la Figuera, Paul R. Eastwood, Sandra Fiol, Fernando Albericio, Pilar Forns
Publikováno v:
QSAR & Combinatorial Science. 27:1267-1273
The immobilization and reactions of indazol-3-carboxylic acid on the solid phase is described. These reactions are of importance since many biologically active compounds contain an indazole core. Here, indazole 3-carboxylic acid was efficiently ancho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53627a7e418c5e48f679a1ae9c3da1e0
https://doi.org/10.1002/qsar.200860005
https://doi.org/10.1002/qsar.200860005
Autor:
Fernando Albericio, Joan-Carles Fernàndez, Aina Colombo, Natalia de la Figuera, Pilar Forns, Dolors Fernández-Forner
Publikováno v:
Tetrahedron Letters. 49:1569-1572
Diastereoselectivity in the oxidation of different 4-thiazolidinones was discussed. Alkylation of these compounds with benzyl bromide was also studied. The stereoselectivity obtained was interpreted by the presence of the sulfoxide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc7f8406b1c55fb206eeaedafdc5bceb
https://doi.org/10.1016/j.tetlet.2008.01.038
https://doi.org/10.1016/j.tetlet.2008.01.038
Autor:
Fernando Albericio, Joan-Carles Fernàndez, Natalia de la Figuera, Pilar Forns, Dolors Fernández-Forner, Aina Colombo
Publikováno v:
Organic Letters. 9:4319-4322
Synthesis and applications of two new nonacid degradable linkers as an alternative to the Wang linker for solid-phase synthesis are described. Resin from linker 2 looks superior to linker 1 in terms of yields for both anchoring of the first building
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8584b42b97a9eca46206ad3c29c99dac
https://doi.org/10.1021/ol701879s
https://doi.org/10.1021/ol701879s
Autor:
Joan-Carles Fernàndez, Laia Solé-Feu, Natalia de la Figuera, Fernando Albericio, Pilar Forns, Dolors Fernández-Forner
Publikováno v:
QSAR & Combinatorial Science. 25:961-965
Solid-phase N-amination of 2-aminopyridin-3/5-yl derivatives supported via an acid labile linker by hydroxylamine-based electrophilic NH 2 + equivalents is described. A comparison of aminating efficiency and stability between O-Mesitylenesulfonyl Hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a1c0a9586af255421d38800ec777fdb
https://doi.org/10.1002/qsar.200520170
https://doi.org/10.1002/qsar.200520170
Autor:
Pilar Forns, Dolors Fernández-Forner, Sandra Fiol, Joan-Carles Fernàndez, Fernando Albericio, Natalia de la Figuera
Publikováno v:
Synlett. 2006:1903-1907
Pictet-Spengler reactions of different α-amino acids in very mild conditions have been studied. Excellent yields were obtained by simply heating the free acids in alcoholic solvents, both in the presence and absence of one equivalent of Et 3 N. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d00cd0bf591dec3b731b4a254dfb994
https://doi.org/10.1055/s-2006-948170
https://doi.org/10.1055/s-2006-948170
Autor:
Natalia de la Figuera, Fernando Albericio, Joan-Carles Fernàndez, Aina Colombo, Pilar Forns, Dolors Fernández-Forner
Publikováno v:
QSAR & Combinatorial Science. 24:913-922
A convenient strategy (preliminary study, preproduction and production) for the solid-phase preparation of a library using 4-iodophenylalanine as a scaffold is described. The aromatic ring was first modified via the Suzuki reaction and the amino posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9448f8809e674ceae7c86151d3d95a
https://doi.org/10.1002/qsar.200420105
https://doi.org/10.1002/qsar.200420105
Suzuki coupling reaction for the solid-phase preparation of 5-substituted nicotinic acid derivatives
Autor:
Pilar Forns, Dolors Fernández-Forner, Laia Solé-Feu, Joan-Carles Fernàndez, Natalia de la Figuera, Fernando Albericio
Publikováno v:
Tetrahedron Letters. 46:581-585
The application of the Suzuki coupling reaction to the preparation of small combinatorial libraries using 5-bromonicotinic acid as a scaffold onto three different types of solid support (Wang, Rink, and BAL resin) is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261eadb3468ffda421da0ecdd3b42b70
https://doi.org/10.1016/j.tetlet.2004.11.153
https://doi.org/10.1016/j.tetlet.2004.11.153
Autor:
Ruben Ventura, Joan-Carles Fernàndez, Marc Vendrell, Fernando Albericio, Francesc Yraola, Miriam Royo, Aina Colombo, A. Pilar Forns, Natalia de la Figuera, Dolors Fernández-Forner
Publikováno v:
QSAR & Combinatorial Science. 23:145-152
The preparation of amine and guanidine derivatives of phenylalaninamide and tryptophanamide as well as benzylamines from BAL, Rink-MBHA, and Rink resins has been performed. Cleavage of the target compound gave significant amounts of byproducts compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7463d46df02dfe749dbad3cc509e661b
https://doi.org/10.1002/qsar.200420013
https://doi.org/10.1002/qsar.200420013