Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Joan X Comella"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Apoptosis is crucial for the correct development of the nervous system. In adulthood, the same protein machinery involved in programmed cell death can control neuronal adaptiveness through modulation of synaptic pruning and synaptic plasticity proces
Externí odkaz:
https://doaj.org/article/b08af3ef15f74400b02c1af182c88c3b
Autor:
Elena Coccia, Isabel Calleja-Yagüe, Laura Planells-Ferrer, Blanca Sanuy, Belen Sanz, Joaquin López-Soriano, Rana S Moubarak, Francina Munell, Bruna Barneda-Zahonero, Joan X Comella, M Jose Pérez-García
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185327 (2017)
Fas Apoptosis Inhibitory Molecule (FAIM) is an evolutionarily highly conserved death receptor antagonist, widely expressed and known to participate in physiological and pathological processes. Two FAIM transcript variants have been characterized to d
Externí odkaz:
https://doaj.org/article/4ea246996fa14cdb8844fdf28fe83edf
Autor:
Paulina Carriba, Joan X Comella
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 10, Pp 1581-1583 (2015)
Externí odkaz:
https://doaj.org/article/d1b039c4ea8e4a99823208e6af8f9459
Autor:
Alessandra di Penta, Beatriz Moreno, Stephanie Reix, Begoña Fernandez-Diez, Maite Villanueva, Oihana Errea, Nagore Escala, Koen Vandenbroeck, Joan X Comella, Pablo Villoslada
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54722 (2013)
BackgroundDemyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage.Methods/principal findingsTo monitor the
Externí odkaz:
https://doaj.org/article/927b9a4c1ce74559acbcc044cb2ad8a1
Autor:
Jisheng Zhang, Junmei Ye, Albert Altafaj, Maria Cardona, Núria Bahi, Marta Llovera, Xavier Cañas, Stuart A Cook, Joan X Comella, Daniel Sanchis
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17998 (2011)
Mitochondrial dysfunction, caspase activation and caspase-dependent DNA fragmentation are involved in cell damage in many tissues. However, differentiated cardiomyocytes repress the expression of the canonical apoptotic pathway and their death during
Externí odkaz:
https://doaj.org/article/2c71090ab483452891e46a4ee5bb5b5a
Autor:
Anna Sirés, Mateo Pazo-González, Joaquín López-Soriano, Ana Méndez, Enrique J. de la Rosa, Pedro de la Villa, Joan X. Comella, Catalina Hernández-Sánchez, Montse Solé
Publikováno v:
Cells, Vol 12, Iss 3, p 487 (2023)
The short and long isoforms of FAIM (FAIM-S and FAIM-L) hold important functions in the central nervous system, and their expression levels are specifically enriched in the retina. We previously described that Faim knockout (KO) mice present structur
Externí odkaz:
https://doaj.org/article/f8efa9779d8f468d9e3853b3a471bad1
Autor:
Kong-Peng Lam, Cristina Hernández, Agustín Ruíz Lasa, Joan X. Comella, Joaquín López-Soriano, Jianxin Huo, Patricia Bogdanov, M. Jose Perez-Garcia, Hugo Ramos, Anna Sirés, Rafael Simó, Shengli Xu, Montse Solé, Mireia Turch-Anguera, Joel Sampedro
Publikováno v:
Journal of neuroscience researchREFERENCES. 99(12)
Fas Apoptotic Inhibitory Molecule protein (FAIM) is a death receptor antagonist and an apoptosis regulator. It encodes two isoforms, namely FAIM-S (short) and FAIM-L (long), both with significant neuronal functions. FAIM-S, which is ubiquitously expr
Autor:
Elena Coccia, Marc Masanas, Joaquín López-Soriano, Miguel F. Segura, Joan X. Comella, M. José Pérez-García
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Apoptosis plays an important role during development, control of tissue homeostasis and in pathological contexts. Apoptosis is executed mainly through the intrinsic pathway or the death receptor pathway, i.e., extrinsic pathway. These processes are t
Publikováno v:
Neurobiology of Disease, Vol 155, Iss, Pp 105366-(2021)
Repositorio Abierto de la UdL
Universitad de Lleida
Scientia
Repositorio Abierto de la UdL
Universitad de Lleida
Scientia
Apoptosi; Motoneurones; Atròfia muscular espinal Apoptosis; Motoneuronas; Atrofia muscular espinal Apoptosis; Motoneurons; Spinal muscular atrophy Spinal Muscular Atrophy (SMA) is a severe neuromuscular disorder caused by loss of the Survival Motor
Autor:
Alba Grayston, Diego Alberti, Koen M.O. Galenkamp, Anna Rosell, Simonetta Geninatti Crich, Elena Oleshkevich, Francesc Teixidor, Nicoletta Protti, Anna Morancho, Clara Viñas, Joan X. Comella, Arpita Saha
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The potential biomedical applications of the MNPs nanohybrids coated with m-carboranylphosphinate (1-MNPs) as a theranostic biomaterial for cancer therapy were tested. The cellular uptake and toxicity profile of 1-MNPs from culture media by human bra