Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Joan X, Comella"'
Autor:
Anna Sirés, Mateo Pazo-González, Joaquín López-Soriano, Ana Méndez, Enrique J. de la Rosa, Pedro de la Villa, Joan X. Comella, Catalina Hernández-Sánchez, Montse Solé
Publikováno v:
Cells, Vol 12, Iss 3, p 487 (2023)
The short and long isoforms of FAIM (FAIM-S and FAIM-L) hold important functions in the central nervous system, and their expression levels are specifically enriched in the retina. We previously described that Faim knockout (KO) mice present structur
Externí odkaz:
https://doaj.org/article/f8efa9779d8f468d9e3853b3a471bad1
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Apoptosis is crucial for the correct development of the nervous system. In adulthood, the same protein machinery involved in programmed cell death can control neuronal adaptiveness through modulation of synaptic pruning and synaptic plasticity proces
Externí odkaz:
https://doaj.org/article/b08af3ef15f74400b02c1af182c88c3b
Publikováno v:
Neurobiology of Disease, Vol 155, Iss , Pp 105366- (2021)
Spinal Muscular Atrophy (SMA) is a severe neuromuscular disorder caused by loss of the Survival Motor Neuron 1 gene (SMN1). Due to this depletion of the survival motor neuron (SMN) protein, the disease is characterized by the degeneration of spinal c
Externí odkaz:
https://doaj.org/article/8ca932a409e549a9bf414e1a25825d86
Autor:
Elena Coccia, Marc Masanas, Joaquín López-Soriano, Miguel F. Segura, Joan X. Comella, M. José Pérez-García
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Apoptosis plays an important role during development, control of tissue homeostasis and in pathological contexts. Apoptosis is executed mainly through the intrinsic pathway or the death receptor pathway, i.e., extrinsic pathway. These processes are t
Externí odkaz:
https://doaj.org/article/22262f9d75ec45029fff23ba8273fc5d
Autor:
Elena Coccia, Isabel Calleja-Yagüe, Laura Planells-Ferrer, Blanca Sanuy, Belen Sanz, Joaquin López-Soriano, Rana S Moubarak, Francina Munell, Bruna Barneda-Zahonero, Joan X Comella, M Jose Pérez-García
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185327 (2017)
Fas Apoptosis Inhibitory Molecule (FAIM) is an evolutionarily highly conserved death receptor antagonist, widely expressed and known to participate in physiological and pathological processes. Two FAIM transcript variants have been characterized to d
Externí odkaz:
https://doaj.org/article/4ea246996fa14cdb8844fdf28fe83edf
Autor:
Paulina Carriba, Joan X Comella
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 10, Pp 1581-1583 (2015)
Externí odkaz:
https://doaj.org/article/d1b039c4ea8e4a99823208e6af8f9459
Autor:
Ana Garcera, Stefka Mincheva, Myriam Gou-Fabregas, Víctor Caraballo-Miralles, Jerònia Lladó, Joan X. Comella, Rosa M. Soler
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 3, Pp 415-426 (2011)
Spinal muscular atrophy (SMA) is a motoneuron disorder characterized by deletions or specific mutations in the Survival Motor Neuron gene (SMN). SMN is ubiquitously expressed and has a general role in the assembly of small nuclear ribonucleoprotein (
Externí odkaz:
https://doaj.org/article/cca0e6b8c4a44401a071870815f597f3
Autor:
Nahuai Badiola, Cristina Malagelada, Nuria Llecha, Juan Hidalgo, Joan X. Comella, Josefa Sabriá, José Rodríguez-Alvarez
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 3, Pp 438-447 (2009)
TNF-α has been reported to be relevant in stroke-induced neuronal death. However the precise function of TNF-α in brain ischemia remains controversial since there are data supporting either a detrimental or a protective effect. Here we show that TN
Externí odkaz:
https://doaj.org/article/76614e7ad24f48e5a2e6a3156be30910
Autor:
Carles eBosch, Albert eMartínez, Núria eMasachs, Cátia M Teixeira, Isabel eFernaud, Fausto eUlloa, Esther ePérez, Carlos eLois, Joan X. Comella, Javier eDeFelipe, Angel eMerchan-Perez, Eduardo eSoriano
Publikováno v:
Frontiers in Neuroanatomy, Vol 9 (2015)
The fine analysis of synaptic contacts is usually performed using transmission electron microscopy (TEM) and its combination with neuronal labeling techniques. However, the complex 3D architecture of neuronal samples calls for their reconstruction fr
Externí odkaz:
https://doaj.org/article/548590a8322047acb8d30846a92cb115
Autor:
Kong-Peng Lam, Cristina Hernández, Agustín Ruíz Lasa, Joan X. Comella, Joaquín López-Soriano, Jianxin Huo, Patricia Bogdanov, M. Jose Perez-Garcia, Hugo Ramos, Anna Sirés, Rafael Simó, Shengli Xu, Montse Solé, Mireia Turch-Anguera, Joel Sampedro
Publikováno v:
Journal of neuroscience researchREFERENCES. 99(12)
Fas Apoptotic Inhibitory Molecule protein (FAIM) is a death receptor antagonist and an apoptosis regulator. It encodes two isoforms, namely FAIM-S (short) and FAIM-L (long), both with significant neuronal functions. FAIM-S, which is ubiquitously expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a733971a4be11d6e330d88801ee406e
https://pubmed.ncbi.nlm.nih.gov/34713467
https://pubmed.ncbi.nlm.nih.gov/34713467