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pro vyhledávání: '"Joan W. Appel"'
Autor:
Matthew D. Cykowski, Suzanne Z. Powell, Joan W. Appel, Anithachristy S. Arumanayagam, Andreana L. Rivera, Stanley H. Appel
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-15 (2018)
Abstract Muscle atrophy with weakness is a core feature of amyotrophic lateral sclerosis (ALS) that has long been attributed to motor neuron loss alone. However, several studies in ALS patients, and more so in animal models, have challenged this assu
Externí odkaz:
https://doaj.org/article/51fcef74f62649fa96612042a6903f79
Autor:
Anithachristy S. Arumanayagam, Matthew D. Cykowski, Andreana L. Rivera, Stanley H. Appel, Joan W. Appel, Suzanne Zein-Eldin Powell
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-15 (2018)
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-15 (2018)
Muscle atrophy with weakness is a core feature of amyotrophic lateral sclerosis (ALS) that has long been attributed to motor neuron loss alone. However, several studies in ALS patients, and more so in animal models, have challenged this assumption wi
Autor:
Leif E. Peterson, Hidehiro Takei, Stanley H. Appel, Matthew D. Cykowski, Ellen Chang, Andreana L. Rivera, Joan W. Appel, Suzanne Zein-Eldin Powell
Publikováno v:
Journal of Neuropathology and Experimental Neurology
To determine the significance of TAR DNA binding protein 43 kDa (TDP-43) pathology in amyotrophic lateral sclerosis (ALS), we examined the whole brains and spinal cords of 57 patients (35 men; 22 women; mean age 63.3 years; 15 patients with c9orf72-a