Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Joan Smith-Sonneborn"'
Autor:
Joan Smith-Sonneborn
Publikováno v:
Current Aging Science
Background: Although telomerase has potential for age-related disease intervention, the overexpression of telomerase in about 90% of cancers, and in HIV virus reservoirs, cautions against se in anti-aging telomerase therapeutics. While multiple revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0aa9ef6d9df530a101a5da21703a0f9
https://doi.org/10.2174/1874609812666190620124324
https://doi.org/10.2174/1874609812666190620124324
Autor:
Joan Smith Sonneborn
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
Stress resistance capacity is a hallmark of longevity protection and survival throughout the plant and animal kingdoms. Latent pathway activation of protective cascades, triggered by environmental challenges to tolerate heat, oxygen deprivation, reac
Externí odkaz:
https://doaj.org/article/a3d1bab60e43448abc93696379bbe075
Autor:
Joan Smith Sonneborn
Publikováno v:
Dose-Response, Vol 8 (2010)
Mimetics of hormetic agents offer a novel approach to adjust dose to minimize the risk of toxic response, and maximize the benefit of induction of at least partial physiological conditioning. Nature selected and preserved those organisms and triggers
Externí odkaz:
https://doaj.org/article/2765800cb30545e79a79cf4bc90b4738
Autor:
Joan Smith Sonneborn
Publikováno v:
Archives in Cancer Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d04f77f3343aa4c39f0ff3ed5eef6cd9
https://doi.org/10.21767/2254-6081-c4-013
https://doi.org/10.21767/2254-6081-c4-013
Autor:
Joan Smith-Sonneborn
Publikováno v:
Biological Effects of Low Level Exposures to Chemicals and Radiation ISBN: 9781315150284
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cb0d8b707ca36fa54d5059f85e6fa1f
https://doi.org/10.1201/9781315150284-2
https://doi.org/10.1201/9781315150284-2
Autor:
Mikal Rutten, Joan Smith Sonneborn
Publikováno v:
Shock. 36:191-195
This study tests the hypothesis that pretreatment and/or posttreatment with 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), an inducer of adenosine monophosphate-activated protein, will extend the golden hour of survival time in rats subjected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e4b3a4d495bf60ae0e0b1badffe136
https://doi.org/10.1097/shk.0b013e3182205d7d
https://doi.org/10.1097/shk.0b013e3182205d7d
Publikováno v:
Shock. 29:42-48
Deltorphin E was investigated as a pharmaceutical intervention in the ischemic hemorrhagic model. To monitor the hemodynamic biomarkers mean arterial pressure (MAP) and heart rate (HR) and to facilitate i.v. injections, rats were surgically fitted wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacb292b6a96b60d3153bf3daa734fc2
https://doi.org/10.1097/shk.0b013e31805cdb70
https://doi.org/10.1097/shk.0b013e31805cdb70
Publikováno v:
American Journal of Pharmacology and Toxicology. 3:4-13
Hormesis refers to the ability of a chemical or physical agent to condition the physiological state of an organism to tolerate stress with low doses of otherwise harmful agents. Evolutionary evidence shows that the survival and longevity of species h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd4517b84933b85f5c4c8c7b5f1ae0d
https://doi.org/10.3844/ajptsp.2008.4.13
https://doi.org/10.3844/ajptsp.2008.4.13
Autor:
Joan Smith-Sonneborn
Publikováno v:
Virology & Mycology.
Telomerase can be touted as the miracle anti-aging enzyme that reverses the age-related attrition of telomere ends. The catalytic subunit of telomerase, TERT telomerase reverse transcriptase, is known to function as an RNA dependent DNA polymerase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8c56ca79bc87162f3f9125680ad58b1
https://doi.org/10.4172/2161-0517.1000150
https://doi.org/10.4172/2161-0517.1000150