Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Joan Sayós"'
Autor:
Laura Viñas-Giménez, Rafael Rincón, Roger Colobran, Xavier de la Cruz, Verónica Paola Celis, José Luis Dapena, Laia Alsina, Joan Sayós, Mónica Martínez-Gallo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory disorder. HLH can be considered as a threshold disease depending on the trigger and the residual NK-cell cytotoxicity. In this study, we analyzed the molecular and funct
Externí odkaz:
https://doaj.org/article/adad2843b85d4f1691acf851788361af
Autor:
Eva Serrano‐Candelas, Erola Ainsua‐Enrich, Arnau Navinés‐Ferrer, Paulo Rodrigues, Alfonso García‐Valverde, Sarah Bazzocco, Irati Macaya, Joaquín Arribas, César Serrano, Joan Sayós, Diego Arango, Margarita Martin
Publikováno v:
Molecular Oncology, Vol 12, Iss 8, Pp 1383-1397 (2018)
Gastrointestinal stromal tumors (GISTs) represent about 80% of the mesenchymal neoplasms of the gastrointestinal tract. Most GISTs contain oncogenic KIT (85%) or PDGFRA (5%) receptors. The kinase inhibitor imatinib mesylate is the preferential treatm
Externí odkaz:
https://doaj.org/article/44732c850c0545fbb2a5fcb190e1048f
Autor:
Diana Rafael, Petra Gener, Fernanda Andrade, Joaquin Seras-Franzoso, Sara Montero, Yolanda Fernández, Manuel Hidalgo, Diego Arango, Joan Sayós, Helena F. Florindo, Ibane Abasolo, Simó Schwartz, Mafalda Videira
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 961-972 (2018)
Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the
Externí odkaz:
https://doaj.org/article/063d196c54e043fe992d7e4cc0565e88
Autor:
Arnau Navinés-Ferrer, Erola Ainsua-Enrich, Eva Serrano-Candelas, Joan Sayós, Margarita Martin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mast cell chemotaxis is essential for cell recruitment to target tissues, where these cells play an important role in adaptive and innate immunity. Stem cell factor (SCF) is a major chemoattractant for mast cells. SCF binds to the KIT receptor, there
Externí odkaz:
https://doaj.org/article/c25a27fab5d042a0b49148b1aa874f1f
Autor:
Simó Schwartz Jr., Ibane Abasolo, Joan Sayós, Diego Arango, Helena Florindo, Patricia González, Francesc Martínez, Joaquin Seras-Franzoso, Petra Gener, Sara Montero, Fernanda Andrade, Diana Rafael, Mafalda Videira
Publikováno v:
Precision Nanomedicine, Vol 1, Iss 2 (2018)
The search for an ideal gene delivery system is a long and laborious process in which several factors from the first idea to final formulation, including main challenges, peaks and troughs, should be deeply taken into consideration to ensure adequate
Externí odkaz:
https://doaj.org/article/d0bb1bed6636471da6c11213d86404a3
Autor:
Petra Gener, Joaquin Seras-Franzoso, Patricia González Callejo, Fernanda Andrade, Diana Rafael, Francesc Martínez, Sara Montero, Diego Arango, Joan Sayós, Ibane Abasolo, Simó Schwartz
Publikováno v:
Stem Cells International, Vol 2018 (2018)
There are remarkable similarities in the description of cancer stem cells (CSCs) and cancer cells with mesenchymal phenotype. Both cell types are highly tumorigenic, resistant against common anticancer treatment, and thought to cause metastatic growt
Externí odkaz:
https://doaj.org/article/ab438e8899c942bd90f48cd7b03a8d0f
Autor:
Aroa Ejarque-Ortiz, Carme Solà, Águeda Martínez-Barriocanal, Simó Schwartz, Margarita Martín, Hugo Peluffo, Joan Sayós
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123928 (2015)
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that include activating and inhibitory receptors. CLM-1 contains two ITIMs and a single immunoreceptor tyrosine-based switch motif (ITSM), although also dis
Externí odkaz:
https://doaj.org/article/b0c46ce15376428381ca5b5ca77a6150
Autor:
Gener, Petra, Gouveia, Luis Pleno, Sabat, Guillem Romero, de Sousa Rafael, Diana Fernandes, Fort, Núria Bergadà, Arranja, Alexandra, Fernández, Yolanda, Prieto, Rafael Miñana, Ortega, Joan Sayos, Arango, Diego, Abasolo, Ibane, Videira, Mafalda, Schwartz, Simo, Jr.
Publikováno v:
In Nanomedicine: Nanotechnology, Biology, and Medicine November 2015 11(8):1883-1892
Autor:
Natalia Lago, Hugo Naya, Daniela Alí-Ruiz, Karen Jansen, Nathalia Vitureira, Juan Andrés Abin-Carriquiry, Hugo Peluffo, Jesús Amo-Aparicio, Luciano Dias Mattos de Souza, Diogo R. Lara, Celia Martin-Otal, Joan Sayós, Natalia Rego, Gabriele Ghisleni, Andrea Arcas-García, María Luciana Negro-Demontel, Ricardo Azevedo da Silva, Fernanda Neutzling Kaufmann, Manuella P. Kaster, Rubèn López-Vales, Dorian B. McGavern, Bruno Pannunzio
Publikováno v:
Proc Natl Acad Sci U S A
A role for microglia in neuropsychiatric diseases, including major depressive disorder (MDD), has been postulated. Regulation of microglial phenotype by immune receptors has become a central topic in many neurological conditions. We explored preclini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d770bc51f4260fecef0c3bbd205e11
https://doi.org/10.1073/pnas.1911816117
https://doi.org/10.1073/pnas.1911816117
Autor:
Laura Donadeu, Laura Viñas-Giménez, Albert Català, Elena Álvarez de la Campa, Mónica Martínez-Gallo, Xavier de la Cruz, Rafael Rincón, Joan Sayós, Roger Colobran, Ana Esteve-Solé, Laia Alsina
Publikováno v:
International Journal of Hematology. 111:440-450
The presence of mutations in PRF1, UNC13D, STX11 and STXBP2 genes in homozygosis or compound heterozygosis results in immune deregulation. Most such cases lead to clinical manifestations of haemophagocytic lymphohistiocytosis (HLH). In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de6642c47c2fe845cf9242b8d9d74dc
https://doi.org/10.1007/s12185-019-02796-7
https://doi.org/10.1007/s12185-019-02796-7