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Autor:
D. Scott Wilbur, Stephen W. Hadley, Leah M. Grant, Michael W. Reed, Mark D. Hylarides, Joan R. Schroeder
Publikováno v:
Bioconjugate Chemistry. 2:435-440
Protein sulfhydryl reactive N-(4-[125I]iodophenethyl)maleimide (IPEM, 5) was obtained from N-[4-(tri-n-butylstannyl)phenethyl]maleimide in 59-100% radiochemical yield. Conjugation of 5 to NR-ML-05 Fab, a murine anti-melanoma antibody Fab fragment tha