Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Joan Mackell"'
Autor:
Elizabeth Pappadopulos, Dalia B. Wajsbrot, Matthieu Boucher, Andrew A. Nierenberg, Rita Prieto, Joan Mackell, Ellen Meier, Martin A Katzman
Publikováno v:
Journal of Clinical Psychopharmacology
Supplemental digital content is available in the text.
Purpose/Background This post hoc analysis examined the time point at which clinically significant improvement in major depressive disorder (MDD) symptoms occurs with desvenlafaxine versus pl
Purpose/Background This post hoc analysis examined the time point at which clinically significant improvement in major depressive disorder (MDD) symptoms occurs with desvenlafaxine versus pl
Autor:
Rana Fayyad, Jose Luis Carrasco, Roger S. McIntyre, Susan G. Kornstein, Joan Mackell, Matthieu Boucher, Maribel Salas, Rita Prieto
Publikováno v:
International Clinical Psychopharmacology. 31:134-146
The chronic course of major depressive disorder (MDD) often impedes the ability of patients to achieve full remission. Return of full functioning is a critical goal of antidepressant pharmacotherapy as the presence of residual depressive symptoms is
Publikováno v:
Current Medical Research and Opinion. 32:587-599
This pooled, post hoc analysis evaluated the efficacy of desvenlafaxine vs placebo in adults with major depressive disorder (MDD) with and without metabolic syndrome, and above or at or below median baseline thyroid-stimulating hormone (TSH) levels.P
Autor:
Ellen Meier, Matthieu Boucher, Raymond W. Lam, Dalia B. Wajsbrot, Joan Mackell, Elizabeth Pappadopulos
Publikováno v:
Journal of psychopharmacology (Oxford, England). 31(9)
Nine randomized, double-blind, placebo-controlled studies of major depressive disorder were pooled to evaluate the effects of desvenlafaxine 50- and 100-mg/d on energy and lassitude in adults with major depressive disorder ( n=4279). Changes from bas
Autor:
Joan Mackell, Yijun Sun, David S. Geldmacher, Jeffrey L. Cummings, Stephen Salloway, Jane Yardley, Jacobo Mintzer
Publikováno v:
American Journal of Alzheimer's Disease & Other Dementias®. 27:421-432
To better understand responses in the large number of US-based patients included in a global trial of donepezil 23 mg/d versus 10 mg/d for moderate-to-severe Alzheimer’s disease (AD), post hoc exploratory analyses were performed to assess the effic
Autor:
Richard Zhang, Yikang Xu, Sharon Richardson, Yijun Sun, Joan Mackell, Gunhild Waldemar, Jeffrey L. Cummings, Sean Knox, Oscar L. Lopez, Roy W. Jones, David Wilkinson, Serge Gauthier
Publikováno v:
International Journal of Geriatric Psychiatry. 26:150-157
Objective To determine whether donepezil treatment (10 mg/day over 24 weeks) is associated with delayed emergence of apathy in patients with mild to moderate Alzheimer's disease (AD) and to explore relationships between donepezil's effects on apathy
Autor:
Serge Gauthier, Roy W. Jones, Gunhild Waldemar, Joan Mackell, Yijun Sun, Richard Zhang, Yikang Xu, David Wilkinson, Oscar L. Lopez, Jeffrey L. Cummings, Sharon Richardson
Publikováno v:
Journal of Alzheimer's Disease. 21:843-851
To better characterize response to donepezil in patients with severe AD, Severe Impairment Battery (SIB) data were pooled from four donepezil clinical trials (N=904). Changes in SIB total and domain scores from baseline to week 24 were compared betwe
Publikováno v:
The journal of nutrition, health & aging. 14:525-530
The Important Perspectives on Alzheimer's Care and Treatment (IMPACT) survey is an assessment in Europe of the attitudes of caregivers, physicians, the general public and payors towards Alzheimer's disease and dementia. This was an Internet-based que
Publikováno v:
The journal of nutrition, health & aging. 14:563-568
Progressive development of pharmacotherapy for Alzheimer's disease (AD) as well as non-pharmacological treatments is critically dependent on the timely recruitment of appropriate subjects for clinical trials. Accordingly, the IMPACT survey sought to
Publikováno v:
The journal of nutrition, health & aging. 14:531-536
Understanding and appreciating the awareness of, and attitudes towards, Alzheimer's disease (AD) in the general public is of paramount importance to those charged with the development of health care policy. Furthermore, it is essential that this poli