Zobrazeno 1 - 10 of 73 pro vyhledávání: '"Joan Mackell"'
1
Speed of Improvement in Symptoms of Depression With Desvenlafaxine 50 mg and 100 mg Compared With Placebo in Patients With Major Depressive Disorder
Autor: Elizabeth Pappadopulos, Dalia B. Wajsbrot, Matthieu Boucher, Andrew A. Nierenberg, Rita Prieto, Joan Mackell, Ellen Meier, Martin A Katzman
Publikováno v: Journal of Clinical Psychopharmacology
Supplemental digital content is available in the text.
Purpose/Background This post hoc analysis examined the time point at which clinically significant improvement in major depressive disorder (MDD) symptoms occurs with desvenlafaxine versus pl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b499657b4c79c7782ab15b71723d59
http://europepmc.org/articles/PMC5596832
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2
An integrated analysis of the efficacy and safety of desvenlafaxine in the treatment of major depressive disorder
Autor: Rana Fayyad, Jose Luis Carrasco, Roger S. McIntyre, Susan G. Kornstein, Joan Mackell, Matthieu Boucher, Maribel Salas, Rita Prieto
Publikováno v: International Clinical Psychopharmacology. 31:134-146
The chronic course of major depressive disorder (MDD) often impedes the ability of patients to achieve full remission. Return of full functioning is a critical goal of antidepressant pharmacotherapy as the presence of residual depressive symptoms is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01da90f5cb5beee6a81ebbb7649cd3d3
https://doi.org/10.1097/yic.0000000000000121
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3
Effect of metabolic syndrome and thyroid hormone on efficacy of desvenlafaxine 50 and 100 mg/d in major depressive disorder
Autor: Joan Mackell, Matthieu Boucher, Roger S. McIntyre, Rana Fayyad
Publikováno v: Current Medical Research and Opinion. 32:587-599
This pooled, post hoc analysis evaluated the efficacy of desvenlafaxine vs placebo in adults with major depressive disorder (MDD) with and without metabolic syndrome, and above or at or below median baseline thyroid-stimulating hormone (TSH) levels.P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc24e79af7dd2e925e9375b24b91119
https://doi.org/10.1185/03007995.2015.1136603
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4
Effect of desvenlafaxine 50 mg and 100 mg on energy and lassitude in patients with major depressive disorder: A pooled analysis
Autor: Ellen Meier, Matthieu Boucher, Raymond W. Lam, Dalia B. Wajsbrot, Joan Mackell, Elizabeth Pappadopulos
Publikováno v: Journal of psychopharmacology (Oxford, England). 31(9)
Nine randomized, double-blind, placebo-controlled studies of major depressive disorder were pooled to evaluate the effects of desvenlafaxine 50- and 100-mg/d on energy and lassitude in adults with major depressive disorder ( n=4279). Changes from bas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8d2850b37be7b2209a6e61020d7ab9
https://pubmed.ncbi.nlm.nih.gov/28718346
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5
Subgroup Analysis of US and Non-US Patients in a Global Study of High-Dose Donepezil (23 mg) in Moderate and Severe Alzheimer’s Disease
Autor: Joan Mackell, Yijun Sun, David S. Geldmacher, Jeffrey L. Cummings, Stephen Salloway, Jane Yardley, Jacobo Mintzer
Publikováno v: American Journal of Alzheimer's Disease & Other Dementias®. 27:421-432
To better understand responses in the large number of US-based patients included in a global trial of donepezil 23 mg/d versus 10 mg/d for moderate-to-severe Alzheimer’s disease (AD), post hoc exploratory analyses were performed to assess the effic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb49da26043056a0f4b3413a39dfad5
https://doi.org/10.1177/1533317512454708
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6
Effect of donepezil on emergence of apathy in mild to moderate Alzheimer's disease
Autor: Richard Zhang, Yikang Xu, Sharon Richardson, Yijun Sun, Joan Mackell, Gunhild Waldemar, Jeffrey L. Cummings, Sean Knox, Oscar L. Lopez, Roy W. Jones, David Wilkinson, Serge Gauthier
Publikováno v: International Journal of Geriatric Psychiatry. 26:150-157
Objective To determine whether donepezil treatment (10 mg/day over 24 weeks) is associated with delayed emergence of apathy in patients with mild to moderate Alzheimer's disease (AD) and to explore relationships between donepezil's effects on apathy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df32552c4d077fc28a1c0102cd0ac335
https://doi.org/10.1002/gps.2507
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7
Effect of Donepezil on Cognition in Severe Alzheimer's Disease: A Pooled Data Analysis
Autor: Serge Gauthier, Roy W. Jones, Gunhild Waldemar, Joan Mackell, Yijun Sun, Richard Zhang, Yikang Xu, David Wilkinson, Oscar L. Lopez, Jeffrey L. Cummings, Sharon Richardson
Publikováno v: Journal of Alzheimer's Disease. 21:843-851
To better characterize response to donepezil in patients with severe AD, Severe Impairment Battery (SIB) data were pooled from four donepezil clinical trials (N=904). Changes in SIB total and domain scores from baseline to week 24 were compared betwe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ccbc8b8972af87c7dadbcc471cbe43
https://doi.org/10.3233/jad-2010-100078
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8
Assessing attitudes and behaviours surrounding Alzheimer’s disease in Europe: Key findings of the important perspectives on Alzheimer’s care and treatment (IMPACT) survey
Autor: Roy W. Jones, K. Berthet, S. Knox, Joan Mackell
Publikováno v: The journal of nutrition, health & aging. 14:525-530
The Important Perspectives on Alzheimer's Care and Treatment (IMPACT) survey is an assessment in Europe of the attitudes of caregivers, physicians, the general public and payors towards Alzheimer's disease and dementia. This was an Internet-based que
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aeca9fea255b4283f61021b69cd0138
https://doi.org/10.1007/s12603-010-0263-y
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9
Physicians and caregivers: Ready and waiting for increased participation in clinical research
Autor: Sandrine Andrieu, S. Knox, Roy W. Jones, Joan Mackell
Publikováno v: The journal of nutrition, health & aging. 14:563-568
Progressive development of pharmacotherapy for Alzheimer's disease (AD) as well as non-pharmacological treatments is critically dependent on the timely recruitment of appropriate subjects for clinical trials. Accordingly, the IMPACT survey sought to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce276d1dfea87efa0e5a35a4a6946735
https://doi.org/10.1007/s12603-010-0269-5
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10
Eolving attitudes to Alzheimer’s disease among the general public and caregivers in Europe: Findings from the IMPACT survey
Autor: Joan Mackell, S. Knox, M. Wortmann, Sandrine Andrieu
Publikováno v: The journal of nutrition, health & aging. 14:531-536
Understanding and appreciating the awareness of, and attitudes towards, Alzheimer's disease (AD) in the general public is of paramount importance to those charged with the development of health care policy. Furthermore, it is essential that this poli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0aacc98be28c2ac4a5675be70bee20
https://doi.org/10.1007/s12603-010-0264-x
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