Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Joan M. Cook-Mills"'
Autor:
Jacob C. Spitznagle, Akadia Kacha-Ochana, Joan M. Cook-Mills, Gabrielle A. Morgan, Lauren M. Pachman
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-6 (2024)
Abstract Background Juvenile dermatomyositis (JDM) is a systemic vasculopathy associated with metabolic derangements and possible increased risk for premature atherosclerosis. Oxidation of low-density lipoprotein (LDL) in the endothelium is an early
Externí odkaz:
https://doaj.org/article/986ecb24e1a24bf6b775cd8a8f13fe5b
Autor:
Matthew T. Walker, Jeffrey C. Bloodworth, Timothy S. Kountz, Samantha L. McCarty, Jeremy E. Green, Ryan P. Ferrie, Jackson A. Campbell, Samantha H. Averill, Kenneth B. Beckman, Leslie C. Grammer, Celeste Eng, Pedro C. Avila, Harold J. Farber, William Rodriguez-Cintron, Jose R. Rodriguez-Santana, Denise Serebrisky, Shannon M. Thyne, Max A. Seibold, Esteban G. Burchard, Rajesh Kumar, Joan M. Cook-Mills
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
BackgroundPrevious research showed that 5-hydroxytryptophan (5HTP), a metabolic precursor of serotonin, reduces allergic lung inflammation by inhibiting eosinophil migration across endothelial monolayers.ObjectiveIt is unknown if serotonin receptors
Externí odkaz:
https://doaj.org/article/ad1b012df26e431ba67b4e2f8672355d
Autor:
Miguel Gonzalez-Visiedo, Roland W. Herzog, Maite Munoz-Melero, Sophia A. Blessinger, Joan M. Cook-Mills, Henry Daniell, David M. Markusic
Publikováno v:
Viruses, Vol 16, Iss 7, p 1125 (2024)
Food allergy (FA) is estimated to impact up to 10% of the population and is a growing health concern. FA results from a failure in the mucosal immune system to establish or maintain immunological tolerance to innocuous dietary antigens, IgE productio
Externí odkaz:
https://doaj.org/article/9a57a1000a05483fb8e70f3d617faad2
Autor:
Jeffery C. Bloodworth, Aki Hoji, Garen Wolff, Rabindra K. Mandal, Nathan W. Schmidt, Jessy S. Deshane, Casey D. Morrow, Kirsten M. Kloepfer, Joan M. Cook-Mills
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
In humans and animals, offspring of allergic mothers have increased responsiveness to allergens. This is blocked in mice by maternal supplementation with α-tocopherol (αT). Also, adults and children with allergic asthma have airway microbiome dysbi
Externí odkaz:
https://doaj.org/article/7b2281d87b2643e8860144b949b14de0
Autor:
Lauren M. Buelow, Akihiko Hoji, Kiet Tat, Lindsay M. Schroeder-Carter, Daniela J. Carroll, Joan M. Cook-Mills
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
Neonatal mice with heterozygous mutations in genes encoding the skin barrier proteins filaggrin and mattrin (flaky tail mice [FT+/−]) exhibit oral peanut-induced anaphylaxis after skin sensitization. As we have previously reported, sensitization in
Externí odkaz:
https://doaj.org/article/10d5feb61da448e1a8d270b4ad6fb3a5
Publikováno v:
Nutrients, Vol 5, Iss 11, Pp 4347-4363 (2013)
Asthma and allergic diseases are complex conditions caused by a combination of genetic and environmental factors. Clinical studies suggest a number of protective dietary factors for asthma, including vitamin E. However, studies of vitamin E in allerg
Externí odkaz:
https://doaj.org/article/da8caae4e5bf425e94ab546df710801e
Publikováno v:
Free Radic Biol Med
Asthma and allergic disease result from interactions of environmental exposures and genetics. Vitamin E is one environmental factor that can modify development of allergy early in life and modify responses to allergen after allergen sensitization. Se
Autor:
Aki Hoji, Rajesh Kumar, James E. Gern, Casper G. Bendixsen, Christine M. Seroogy, Joan M. Cook-Mills
Publikováno v:
The journal of allergy and clinical immunology. Global. 1(3)
Allergen-sensitized pregnant mice have increased plasma levels of the lipids β-glucosylceramides (βGlcCers) that are transplacentally transferred to the fetus, increased subsets of proinflammatory dendritic cells in the fetal liver and pup lung, an
Publikováno v:
Advanced Biology. :2200296
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(10)
In humans and mice, offspring of allergic mothers are predisposed to development of allergy. In mice, allergic mothers have elevated β-glucosylceramides (βGlcCers) that are transported to the fetus via the placenta and to offspring via milk. Elevat