Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Joan M. Carboni"'
Autor:
Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang
Supplementary Tables S1-S4. Supplementary Table S1: Association of gene mutations, IRS2 copy number gain, and gene expression level with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S2: The relationship between KRAS, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf361093d6982b4e2b58d163680e344
https://doi.org/10.1158/1535-7163.22503652.v1
https://doi.org/10.1158/1535-7163.22503652.v1
Autor:
Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang
Supplementary Figures S1-S5. Supplementary Figure S1. Similarity of CNV profiles are seen from both CRC cell lines and CRC primary tumor samples with highlight on chromosome 13 copy number gain. Supplementary Figure S2: The RNA expression levels comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2952872ef51281f0ac1ebaa8a0d3bbc8
https://doi.org/10.1158/1535-7163.22503658.v1
https://doi.org/10.1158/1535-7163.22503658.v1
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
Legends for Supplementary Figures 1-2, Tables 1-6 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2c544b8ee16f58175edab160b033f4
https://doi.org/10.1158/1535-7163.22485218
https://doi.org/10.1158/1535-7163.22485218
Autor:
Adrian V. Lee, Craig R. Fairchild, Marco M. Gottardis, Ricardo M. Attar, Joan M. Carboni, Isere Kuiatse, Hyun-Jung Kim, Beate C. Litzenburger
Purpose: This study aimed to test the ability of a new insulin-like growth factor receptor (IGF-IR) tyrosine kinase inhibitor, BMS-536924, to reverse the ability of constitutively active IGF-IR (CD8-IGF-IR) to transform MCF10A cells, and to examine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a6b9d7ef2a7b814acbf857a5511d09
https://doi.org/10.1158/1078-0432.c.6517204
https://doi.org/10.1158/1078-0432.c.6517204
Autor:
Paul Haluska, Scott H. Kaufmann, Charles Erlichman, Marco M. Gottardis, Douglas D. Ross, Jennifer D. Tibodeau, Takeo Nakanishi, Cynthia Ten Eyck, Yan W. Asmann, Karen Flatten, Joan M. Carboni, Fei Huang, Xiaonan Hou
Preclinical investigations have identified insulin-like growth factor (IGF) signaling as a key mechanism for cancer growth and resistance to clinically useful therapies in multiple tumor types including breast cancer. Thus, agents targeting and block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbd5465fc9b4aaf920a287c41441376
https://doi.org/10.1158/1535-7163.c.6531158.v1
https://doi.org/10.1158/1535-7163.c.6531158.v1
Autor:
Paul Haluska, Marco M. Gottardis, Joan M. Carboni, Kristina A. Jacob, Sergio E. Gonzalez, S. John Weroha, Sean C. Harrington, Xiaonan Hou, Marc A. Becker
PDF file - 2.5MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f7eff3dd75daad329db276574f4fc2
https://doi.org/10.1158/1078-0432.22446702.v1
https://doi.org/10.1158/1078-0432.22446702.v1
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
Supplementary Tables 1-6 from BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb573ea3b1cac91d2db653d78a7f6e8
https://doi.org/10.1158/1535-7163.22485209.v1
https://doi.org/10.1158/1535-7163.22485209.v1
Autor:
Paul Haluska, Scott H. Kaufmann, Charles Erlichman, Marco M. Gottardis, Douglas D. Ross, Jennifer D. Tibodeau, Takeo Nakanishi, Cynthia Ten Eyck, Yan W. Asmann, Karen Flatten, Joan M. Carboni, Fei Huang, Xiaonan Hou
Supplementary Figure 1 from Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d25a4bed8d23420c5d7d440792c19f
https://doi.org/10.1158/1535-7163.22483487.v1
https://doi.org/10.1158/1535-7163.22483487.v1
Autor:
Adrian V. Lee, Mothaffar F. Rimawi, Michael T. Lewis, Jenny C. Chang, Fei Huang, Marco M. Gottardis, Joan M. Carboni, Tao Wang, Susan G. Hilsenbeck, Bonita T. Chan, Anna Tsimelzon, Chad J. Creighton, Beate C. Litzenburger
Supplementary Figures S1-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5158217aa2a26bd0a8fdfcb7394a54a1
https://doi.org/10.1158/1078-0432.22442280.v1
https://doi.org/10.1158/1078-0432.22442280.v1
Autor:
Paul Haluska, Marco M. Gottardis, Joan M. Carboni, Kristina A. Jacob, Sergio E. Gonzalez, S. John Weroha, Sean C. Harrington, Xiaonan Hou, Marc A. Becker
Purpose: To improve the significance of insulin-like growth factor–binding protein 5 (IGFBP-5) as a prognostic and potentially predictive marker in patients with breast cancer.Experimental Design: Increased IGFBP-5 expression was identified in MCF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174000609ba2de33ebef6a3a235ecaa6
https://doi.org/10.1158/1078-0432.c.6520839.v1
https://doi.org/10.1158/1078-0432.c.6520839.v1