Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Joan M Lappe"'
Autor:
Olja Grgic, Matthew R. Gazzara, Alessandra Chesi, Carolina Medina-Gomez, Diana L. Cousminer, Jonathan A. Mitchell, Vid Prijatelj, Jard de Vries, Enisa Shevroja, Shana E. McCormack, Heidi J. Kalkwarf, Joan M. Lappe, Vicente Gilsanz, Sharon E. Oberfield, John A. Shepherd, Andrea Kelly, Soroosh Mahboubi, Fabio R. Faucz, Richard A. Feelders, Frank H. de Jong, Andre G. Uitterlinden, Jenny A. Visser, Louis R. Ghanem, Eppo B. Wolvius, Leo J. Hofland, Constantine A. Stratakis, Babette S. Zemel, Yoseph Barash, Struan F. A. Grant, Fernando Rivadeneira
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Olja Grgic, Matthew Gazzara, and Alessandra Chesi et al. perform a genome-wide association study meta-analysis for skeletal age in two pediatric cohorts. They observe that variation in the adrenal gene, CYP11B1, impacts its alternative splicing, sugg
Externí odkaz:
https://doaj.org/article/828a46ae925244b793f2682e780f9eb6
Autor:
Wen Qian, Roman Schmidt, Joseph A. Turner, Sue P. Bare, Joan M. Lappe, Robert R. Recker, Mohammed P. Akhter
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101604- (2022)
The goal of this study is to investigate the causes of osteoporosis-related skeletal fragility in postmenopausal women. We hypothesize that bone fragility in these individuals is largely due to mineral, and/or intrinsic material properties in the ost
Externí odkaz:
https://doaj.org/article/d7f9103a705b46f5b3d600cf9795bc2d
Autor:
Diana L. Cousminer, Yadav Wagley, James A. Pippin, Ahmed Elhakeem, Gregory P. Way, Matthew C. Pahl, Shana E. McCormack, Alessandra Chesi, Jonathan A. Mitchell, Joseph M. Kindler, Denis Baird, April Hartley, Laura Howe, Heidi J. Kalkwarf, Joan M. Lappe, Sumei Lu, Michelle E. Leonard, Matthew E. Johnson, Hakon Hakonarson, Vicente Gilsanz, John A. Shepherd, Sharon E. Oberfield, Casey S. Greene, Andrea Kelly, Deborah A. Lawlor, Benjamin F. Voight, Andrew D. Wells, Babette S. Zemel, Kurt D. Hankenson, Struan F. A. Grant
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-32 (2021)
Abstract Background Bone accrual impacts lifelong skeletal health, but genetic discovery has been primarily limited to cross-sectional study designs and hampered by uncertainty about target effector genes. Here, we capture this dynamic phenotype by m
Externí odkaz:
https://doaj.org/article/165481b925744dddb170926499acd9cc
Autor:
Sanchita Agarwal, Stephanie Shiau, Mafo Kamanda‐Kosseh, Mariana Bucovsky, Nayoung Kil, Joan M. Lappe, Julie Stubby, Robert R. Recker, X. Edward Guo, Elizabeth Shane, Adi Cohen
Publikováno v:
Journal of Bone and Mineral Research. 38:35-47
Premenopausal women with idiopathic osteoporosis (PreMenIOP) have marked deficits in skeletal microstructure. We have reported that sequential treatment with teriparatide and denosumab improves central skeletal bone mineral density (BMD) by dual-ener
Autor:
Sanchita Agarwal, Elizabeth Shane, Thomas Lang, Stephanie Shiau, Mafo Kamanda-Kosseh, Mariana Bucovsky, Joan M Lappe, Julie Stubby, Robert R Recker, Yizhong Hu, Zexi Wang, X Edward Guo, Adi Cohen
Publikováno v:
J Clin Endocrinol Metab
Context Premenopausal women with idiopathic osteoporosis (PreMenIOP) have marked deficits in bone density, microstructure, and strength. Objective To define effects of treatment with teriparatide followed by denosumab on lumbar spine (LS) volumetric
Autor:
Wen Qian, Sonja Gamsjaeger, Eleftherios P. Paschalis, Laura A. Graeff-Armas, Sue P. Bare, Joseph A. Turner, Joan M. Lappe, Robert R. Recker, Mohammed P. Akhter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8fc22749ef06081f8a3b32f0d7db143
https://doi.org/10.2139/ssrn.4328036
https://doi.org/10.2139/ssrn.4328036
Autor:
Sharon L McDonnell, Carole A Baggerly, Christine B French, Leo L Baggerly, Cedric F Garland, Edward D Gorham, Bruce W Hollis, Donald L Trump, Joan M Lappe
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199265 (2018)
BACKGROUND:While numerous epidemiologic studies have found an association between higher serum 25-hydroxyvitamin D [25(OH)D] concentrations and lower breast cancer risk, few have assessed this association for concentrations >40 ng/ml. OBJECTIVE:To in
Externí odkaz:
https://doaj.org/article/7fb283cd81f2415794b8294c03ecd9a5
Autor:
Sharon L McDonnell, Carole Baggerly, Christine B French, Leo L Baggerly, Cedric F Garland, Edward D Gorham, Joan M Lappe, Robert P Heaney
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201078 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0152441.].
Externí odkaz:
https://doaj.org/article/582a03a82df345908f0756b6c31a8b2e
Autor:
Robert R. Recker, Joan M. Lappe, Sanchita Agarwal, Stephanie Shiau, Julie Stubby, Mariana Bucovsky, Mafo Kamanda-Kosseh, Adi Cohen, Elizabeth Shane
Publikováno v:
J Clin Endocrinol Metab
Context We have previously reported that teriparatide is associated with substantial increases in bone mineral density (BMD) at the lumbar spine (LS), total hip (TH), and femoral neck (FN) and small declines at the distal radius in 41 premenopausal w
Autor:
Joan M. Lappe, Hanh Nguyen-Vaselaar
Publikováno v:
The Journal for Nurse Practitioners. 17:1281-1284
In this pilot project, patient-selected SMART (Specific, Measurable, Attainable, Relevant, Time-bound) goals were used a to increase self-reported physical activity and decrease hemoglobin A1C (HbA1C) in patients with type II diabetes (T2DM). We asse