Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Joan Levine"'
Autor:
Jean Pierre J. Issa, John A. Baron, Gail McKeown-Eyssen, Dennis Ahnen, Elizabeth L. Barry, Robert W. Haile, Jiang Gui, Xinli Chen, Randala Hamdan, Lanlan Shen, A. Joan Levine, Maria V. Grau, Kristin Wallace
Perspectives on This Article from Association between Folate Levels and CpG Island Hypermethylation in Normal Colorectal Mucosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a16b9e156f4e3e31ffad6e3c3a190a9
https://doi.org/10.1158/1940-6207.22523152
https://doi.org/10.1158/1940-6207.22523152
Autor:
Jean Pierre J. Issa, John A. Baron, Gail McKeown-Eyssen, Dennis Ahnen, Elizabeth L. Barry, Robert W. Haile, Jiang Gui, Xinli Chen, Randala Hamdan, Lanlan Shen, A. Joan Levine, Maria V. Grau, Kristin Wallace
Gene-specific promoter methylation of several genes occurs in aging normal tissues and may predispose to tumorigenesis. In the present study, we investigate the association of blood folate levels and dietary and lifestyle factors with CpG island (CGI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478e437aae6baffe11341f9dd0ec62a0
https://doi.org/10.1158/1940-6207.c.6543616.v1
https://doi.org/10.1158/1940-6207.c.6543616.v1
Autor:
Robert W. Haile, Cornelia M. Ulrich, Paul J. Limburg, John A. Baron, Loic Le Marchand, John L. Hopper, Maria Elena Martinez, Polly Newcomb, Peter T. Campbell, Jenny N. Poynter, David J. Duggan, Kathleen Kennedy, David V. Conti, Won Lee, Jane C. Figueiredo, A. Joan Levine
Background: Folate-associated one-carbon metabolism (FOCM) may play an important role in colorectal carcinogenesis. Variation in FOCM genes may explain some of the underlying risk of colorectal cancer.Methods: This study utilized data from 1,805 popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6be57c79d9e04749fe7035a8ffbf570
https://doi.org/10.1158/1055-9965.c.6514885.v1
https://doi.org/10.1158/1055-9965.c.6514885.v1
Autor:
Kimberly D. Siegmund, Peter W. Laird, Joanne P. Young, John L. Hopper, Robert W. Haile, John A. Baron, Dennis J. Ahnen, Graham Casey, Peter T. Campbell, Polly A. Newcomb, Bharati Bapat, Teresa Selander, Steven Gallinger, Darshana Daftary, Noralane M. Lindor, Loic Le Marchand, Mariana C. Stern, Amit D. Joshi, Christophe Rosty, Mark Clendenning, Rhiannon Walters, Daniel D. Buchanan, Tiffany I. Long, A. Joan Levine, Daniel J. Weisenberger
Background: The CpG island methylator phenotype (CIMP) represents a subset of colorectal cancers characterized by widespread aberrant DNA hypermethylation at select CpG islands. The risk factors and environmental exposures contributing to etiologic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01ee8cd44174a09d93a742ac6cbbbab
https://doi.org/10.1158/1055-9965.c.6516348.v1
https://doi.org/10.1158/1055-9965.c.6516348.v1
Autor:
Robert W. Haile, John A. Baron, David J. Duggan, John L. Hopper, Mark A. Jenkins, John D. Potter, Polly A. Newcomb, Michelle Cotterchio, Loic Le Marchand, Paul Limburg, A. Joan Levine, Peter T. Campbell, David V. Conti, Won H. Lee, Jane C. Figueiredo, Elizabeth T. Jacobs, Jenny N. Poynter
Supplementary Table 1 from Genetic Variation in the Vitamin D Receptor (VDR) and the Vitamin D–Binding Protein (GC) and Risk for Colorectal Cancer: Results from the Colon Cancer Family Registry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22141794e6039618a23128c759791a30
https://doi.org/10.1158/1055-9965.22435345.v1
https://doi.org/10.1158/1055-9965.22435345.v1
Autor:
Kimberly D. Siegmund, Peter W. Laird, Joanne P. Young, John L. Hopper, Robert W. Haile, John A. Baron, Dennis J. Ahnen, Graham Casey, Peter T. Campbell, Polly A. Newcomb, Bharati Bapat, Teresa Selander, Steven Gallinger, Darshana Daftary, Noralane M. Lindor, Loic Le Marchand, Mariana C. Stern, Amit D. Joshi, Christophe Rosty, Mark Clendenning, Rhiannon Walters, Daniel D. Buchanan, Tiffany I. Long, A. Joan Levine, Daniel J. Weisenberger
Supplemental Table 1. Distribution of CIMP status1 by selected characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfb3925df6d3545e6bfb4f8e1ce9c41
https://doi.org/10.1158/1055-9965.22438392.v1
https://doi.org/10.1158/1055-9965.22438392.v1
Autor:
Robert W. Haile, Cornelia M. Ulrich, Paul J. Limburg, John A. Baron, Loic Le Marchand, John L. Hopper, Maria Elena Martinez, Polly Newcomb, Peter T. Campbell, Jenny N. Poynter, David J. Duggan, Kathleen Kennedy, David V. Conti, Won Lee, Jane C. Figueiredo, A. Joan Levine
Supplementary Table 1 from A Candidate Gene Study of Folate-Associated One Carbon Metabolism Genes and Colorectal Cancer Risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9d263aa027205e86dd7bc90c992d77
https://doi.org/10.1158/1055-9965.22435369.v1
https://doi.org/10.1158/1055-9965.22435369.v1
Autor:
Robert W. Haile, Cornelia M. Ulrich, Paul J. Limburg, John A. Baron, Loic Le Marchand, John L. Hopper, Maria Elena Martinez, Polly Newcomb, Peter T. Campbell, Jenny N. Poynter, David J. Duggan, Kathleen Kennedy, David V. Conti, Won Lee, Jane C. Figueiredo, A. Joan Levine
Supplementary Table 2 from A Candidate Gene Study of Folate-Associated One Carbon Metabolism Genes and Colorectal Cancer Risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4647d5eee2724409a6b2527b1f24b532
https://doi.org/10.1158/1055-9965.22435366.v1
https://doi.org/10.1158/1055-9965.22435366.v1
Autor:
Robert W. Haile, John A. Baron, David J. Duggan, John L. Hopper, Mark A. Jenkins, John D. Potter, Polly A. Newcomb, Michelle Cotterchio, Loic Le Marchand, Paul Limburg, A. Joan Levine, Peter T. Campbell, David V. Conti, Won H. Lee, Jane C. Figueiredo, Elizabeth T. Jacobs, Jenny N. Poynter
Epidemiologic evidence supports a role for vitamin D in colorectal cancer (CRC) risk. Variants in vitamin D–related genes might modify the association between vitamin D levels and CRC risk. In this analysis, we did a comprehensive evaluation of com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067b27ff135986b8d91e669838820100
https://doi.org/10.1158/1055-9965.c.6514873.v1
https://doi.org/10.1158/1055-9965.c.6514873.v1
Autor:
A. Joan Levine, David V. Conti, Allyson Templeton, Jun Wang, Stan G. Louie, Polly A. Newcomb, Graham Casey, Robert W. Haile, John A. Baron, Fredrick R. Schumacher, Jane C. Figueiredo, Isaac Asante
Publikováno v:
Genet Epidemiol
Experimental, observational, and clinical trials support a critical role of folate one-carbon metabolism (FOCM) in colorectal cancer (CRC) development. In this report, we focus on understanding the relationship between common genetic variants and met