Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Joan Kwakkel"'
Autor:
W Edward Visser, Cíntia R Bombardieri, Chantal Zevenbergen, Sander Barnhoorn, Alexandre Ottaviani, Ingrid van der Pluijm, Renata Brandt, Ellen Kaptein, Ramona van Heerebeek, Hans van Toor, George A Garinis, Robin P Peeters, Marco Medici, Willy van Ham, Wilbert P Vermeij, Monique C de Waard, Ronald R de Krijger, Anita Boelen, Joan Kwakkel, John J Kopchick, Edward O List, Joost P M Melis, Veerle M Darras, Martijn E T Dollé, Gijsbertus T J van der Horst, Jan H J Hoeijmakers, Theo J Visser
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149941 (2016)
DNA damage contributes to the process of aging, as underscored by premature aging syndromes caused by defective DNA repair. Thyroid state changes during aging, but underlying mechanisms remain elusive. Since thyroid hormone (TH) is a key regulator of
Externí odkaz:
https://doaj.org/article/ca420b0d4f254e4db9aa43c0a8d08565
Publikováno v:
Chronobiology international, 32(2), 211-224. Marcel Dekker Inc.
Annual Review of Chronopharmacology, 32(2), 211-224. Marcel Dekker
Annual Review of Chronopharmacology, 32(2), 211-224. Marcel Dekker
It is assumed that in mammals the circadian rhythms of peripheral clocks are synchronized to the environment via neural, humoral and/or behavioral outputs of the central pacemaker in the suprachiasmatic nucleus of the hypothalamus (SCN). With regard
Autor:
Anne H van der Spek, Emmely M de Vries, Olga V. Surovtseva, Mieke van Beeren, Anita Boelen, Mariëtte T. Ackermans, Flavia Fonseca Bloise, Eric Fliers, Joan Kwakkel
Publikováno v:
Journal of endocrinology, 233(1), 25-36. Society for Endocrinology
Illness induces major modifications in central and peripheral thyroid hormone (TH) metabolism, so-called nonthyroidal illness syndrome (NTIS). As a result, organ-specific changes in local TH availability occur depending on the type and severity of il
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336055e11fc31a8cf9fad32ef170154b
https://pure.amc.nl/en/publications/tissue-thyroid-hormone-metabolism-is-differentially-regulated-during-illness-in-mice(7b19a981-df52-4e94-9d44-289868aca785).html
https://pure.amc.nl/en/publications/tissue-thyroid-hormone-metabolism-is-differentially-regulated-during-illness-in-mice(7b19a981-df52-4e94-9d44-289868aca785).html
Autor:
Clementine J J, van Zeijl, Olga V, Surovtseva, Joan, Kwakkel, Hermina C, van Beeren, J H Duncan, Bassett, J H, Duncan Bassett, Graham R, Williams, Wilmar M, Wiersinga, Eric, Fliers, Anita, Boelen
Publikováno v:
American journal of physiology. Endocrinology and metabolism, 307(6), E527-E537. American Physiological Society
Thyrostimulin, a putative glycoprotein hormone, comprises the subunits GPA2 and GPB5 and activates the TSH receptor (TSHR). The observation that proinflammatory cytokines stimulate GPB5 transcription suggested a role for thyrostimulin in the pathogen
Publikováno v:
Endocrinology, 155(7), 2725-2734. The Endocrine Society
Deiodinase type 2 (D2) is a thyroid hormone-activating enzyme converting the prohormone T-4 into the active hormone T-3. In the present study, we show for the first time that D2 is up-regulated in the mouse liver during acute and chronic inflammation
Autor:
Andries Kalsbeek, Perry Barrett, Ellen A. Fliers, Anita Boelen, Joan Kwakkel, E. M. de Vries, Leslie Eggels
Publikováno v:
Endocrinology, 155(5), 2000-2008. The Endocrine Society
Endocrinology, 155(5), 2000-8. The Endocrine Society
Endocrinology, 155(5), 2000-8. The Endocrine Society
The enzyme type 2 deiodinase (D2) is a major determinant of T3 production in the central nervous system. It is highly expressed in tanycytes, a specialized cell type lining the wall of the third ventricle. During acute inflammation, the expression of
Autor:
George A. Garinis, Veerle Darras, Robin P. Peeters, Hans van Toor, Ramona van Heerebeek, Martijn E.T. Dollé, Anita Boelen, Sander Barnhoorn, Joan Kwakkel, Renata M. C. Brandt, John J. Kopchick, Joost P.M. Melis, W. Edward Visser, Ellen Kaptein, Edward O. List, Theo J. Visser, Marco Medici, Ingrid van der Pluijm, Wilbert P. Vermeij, Alexandre Ottaviani, Gijsbertus T. J. van der Horst, Monique C. de Waard, Jan H.J. Hoeijmakers, Ronald R. de Krijger, Willy van Ham, Cíntia R. Bombardieri, Chantal Zevenbergen
Publikováno v:
PLoS ONE, 11(3). Public Library of Science
PLoS ONE, 11(3):e0149941. Public Library of Science
PLoS ONE
PLoS One (print), 11(3). Public Library of Science
PLoS ONE, Vol 11, Iss 3, p e0149941 (2016)
Visser, W E, Bombardieri, C R, Zevenbergen, C, Barnhoorn, S, Ottaviani, A, van der Pluijm, I, Brandt, R, Kaptein, E, van Heerebeek, R, van Toor, H, Garinis, G A, Peeters, R P, Medici, M, van Ham, W, Vermeij, W P, de Waard, M C, de Krijger, R R, Boelen, A, Kwakkel, J, Kopchick, J J, List, E O, Melis, J P M, Darras, V M, Dolle, M E T, van der Horst, G T J, Hoeijmakers, J H J & Visser, T J 2016, ' Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging ', PLoS ONE, vol. 11, no. 3, e0149941 . https://doi.org/10.1371/journal.pone.0149941
PLoS ONE [E], 11(3). Public Library of Science
PLoS ONE, 11(3):e0149941. Public Library of Science
PLoS ONE
PLoS One (print), 11(3). Public Library of Science
PLoS ONE, Vol 11, Iss 3, p e0149941 (2016)
Visser, W E, Bombardieri, C R, Zevenbergen, C, Barnhoorn, S, Ottaviani, A, van der Pluijm, I, Brandt, R, Kaptein, E, van Heerebeek, R, van Toor, H, Garinis, G A, Peeters, R P, Medici, M, van Ham, W, Vermeij, W P, de Waard, M C, de Krijger, R R, Boelen, A, Kwakkel, J, Kopchick, J J, List, E O, Melis, J P M, Darras, V M, Dolle, M E T, van der Horst, G T J, Hoeijmakers, J H J & Visser, T J 2016, ' Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging ', PLoS ONE, vol. 11, no. 3, e0149941 . https://doi.org/10.1371/journal.pone.0149941
PLoS ONE [E], 11(3). Public Library of Science
DNA damage contributes to the process of aging, as underscored by premature aging syndromes caused by defective DNA repair. Thyroid state changes during aging, but underlying mechanisms remain elusive. Since thyroid hormone (TH) is a key regulator of
Autor:
Ewout Foppen, Lei Pei, Joan Kwakkel, Andries Kalsbeek, Eveline Bruinstroop, Anke J. Borgers, Mariëtte T. Ackermans, Eric Fliers, Anneke Alkemade
Publikováno v:
Diabetes
Diabetes, 61, 1043-1050. American Diabetes Association Inc.
Diabetes, 61(5), 1043-1050. American Diabetes Association Inc.
Diabetes, 61, 1043-50
Diabetes, 61, 5, pp. 1043-50
Diabetes, 61, 1043-1050. American Diabetes Association Inc.
Diabetes, 61(5), 1043-1050. American Diabetes Association Inc.
Diabetes, 61, 1043-50
Diabetes, 61, 5, pp. 1043-50
Excessive secretion of triglyceride-rich very low-density lipoproteins (VLDL-TG) contributes to diabetic dyslipidemia. Earlier studies have indicated a possible role for the hypothalamus and autonomic nervous system in the regulation of VLDL-TG. In t
Autor:
Xander Vos, Evita Belegri, Andries Kalsbeek, Eric Fliers, Joan Kwakkel, Olga V. Surovtseva, Anita Boelen, Erno Vreugdenhil, Dirk-Jan Saaltink, Mieke van Beeren
Publikováno v:
Thyroid, 22, 192-199. Mary Ann Liebert Inc.
Thyroid, 22(2), 192-199. Mary Ann Liebert Inc.
Thyroid, 22(2), 192-199. Mary Ann Liebert Inc.
Background: Decreased serum leptin has been proposed as a critical signal initiating the neuroendocrine response to fasting. Leptin administration partially reverses the fasting-induced suppression of the hypothalamus-pituitary-thyroid axis at the ce
Autor:
Hermina C. van Beeren, Mariëtte T. Ackermans, Joan Kwakkel, Wilmar M. Wiersinga, Eric Fliers, Anita Boelen
Publikováno v:
Thyroid, 22(12), 1275-1282. Mary Ann Liebert Inc.
Background: The iodine-containing drug amiodarone (Amio) and its noniodine containing analogue dronedarone (Dron) are potent antiarrhythmic drugs. Previous in vivo and in vitro studies have shown that the major metabolite of Amio, desethylamiodarone,