Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joan K. Mattox"'
Publikováno v:
Journal of toxicology and environmental health. 38(1)
The disposition of dichloroacetic acid (DCA) was investigated in Fischer 344 rats over the 48 h after oral gavage of 282 mg/kg of 1- or 2-[14C]-DCA (1-DCA or 2-DCA) and 28.2 mg/kg of 2-DCA. DCA was absorbed quickly, and the major route of disposition
Publikováno v:
Environment International, Vol 5, Iss 4, Pp 373-376 (1981)
Adult male, inbred, disease-free cats of uniform age and size were exposed eight hours per day, seven days per week to a 1 : 18 dilution of diesel exhaust emissions. After one year of exposure, the animals were removed from the chambers for measureme
Publikováno v:
Toxicology and Applied Pharmacology. 78:428-435
1,2-[1,2- 14 C]Dichloroethane was metabolized by rat hepatic microsomes to products that irreversibly bound polynucleotides. The polynucleotides were then enzymatically hydrolyzed and the products separated by a high-performance liquid chromatograph
Publikováno v:
Fundamental and Applied Toxicology. 6:447-453
Chlorinated and brominated haloacetonitriles (HAN), known drinking water contaminants which form during chlorine disinfection, were investigated for genotoxic activity. The HAN produced DNA strand breaks in cultured human lymphoblastic (CCRF-CEM) cel
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 24:156-160
Despite the relatively low toxicity of ammonium sulfate in experimental animals, it cannot be concluded that increased sulfuric acid production is harmless to human health. Many other pollutants are present in ambient air with possible synergistic ef
Publikováno v:
Journal of toxicology and environmental health. 13(4-6)
Haloacetonitriles, contaminants present in chlorinated drinking water, were administered orally to rats, and the urinary excretion of thiocyanate was measured as an index of cyanide release. The urinary excretion of thiocyanate accounted for 14.2% of
Autor:
J. M. Lockard, Joan K. Mattox, P. Kaur, P.S. Sabharwal, Lofton McMillan, Michael A. Pereira, C. Lee-Stephens
Publikováno v:
Mutation research. 104(6)
Particulate matter was collected from the emissions of a diesel-powered engine and the organic components were extracted. The extract induced a dose-related increase in sister-chromatid exchanges in human lymphocytes with a potency of about one-fifth
Publikováno v:
Journal of applied toxicology : JAT. 5(5)
Long-term inhalation studies were carried out to evaluate the toxic pulmonary effects of diesel engine emissions. Cats were exposed for over 2 years to whole, diluted diesel exhaust at levels expected to produce frank toxic effects. During the first