Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joan Greve"'
Autor:
Tejaswi Worlikar, Mishal Mendiratta-Lala, Eli Vlaisavljevich, Ryan Hubbard, Jiaqi Shi, Timothy L. Hall, Clifford S. Cho, Fred T. Lee, Joan Greve, Zhen Xu
Publikováno v:
BME Frontiers, Vol 2020 (2020)
Objective and Impact Statement. This is the first longitudinal study investigating the effects of histotripsy on local tumor progression in an in vivo orthotopic, immunocompetent rat hepatocellular carcinoma (HCC) model. Introduction. Histotripsy is
Externí odkaz:
https://doaj.org/article/b0b68c989cae4991b60a302dbb5b372d
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 55K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc838fa47a9d23267b37a858ed4d3f8
https://doi.org/10.1158/1078-0432.22447710
https://doi.org/10.1158/1078-0432.22447710
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 77K, Cell viability following treatment with GNE-317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b14e8b2c62065f86e47c21ee5d4697a
https://doi.org/10.1158/1078-0432.22447713.v1
https://doi.org/10.1158/1078-0432.22447713.v1
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 60K, Plasma Concentrations, Brain Concentrations and Brain-to-Plasma Ratio Measured at the End of Study (42 days) 2 hours Following the Last Daily PO Administration of GNE-317 (40 mg/kg), GDC-0941 (250 mg/kg) or GDC-0980 (10 mg/kg) to GS2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1649707918904ad8cbd83771a80366bc
https://doi.org/10.1158/1078-0432.22447701
https://doi.org/10.1158/1078-0432.22447701
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 116K, Plot of CNS-MPO score vs. efflux ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec1963a4dc8dbcd09c67292559efb78
https://doi.org/10.1158/1078-0432.22447716.v1
https://doi.org/10.1158/1078-0432.22447716.v1
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 57K, Selectivity of GNE-317 against a Panel of 59 Kinases. GNE-317 was Tested at 1 �M in the Invitrogen SelectScreen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29316f2a68ac338de6dc314e3ac4eb34
https://doi.org/10.1158/1078-0432.22447698.v1
https://doi.org/10.1158/1078-0432.22447698.v1
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 47K, Anti-proliferative EC50's for GNE-317 against a Panel of Nine Glioma Cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927b2437f8d62a766f1d9f3c72bee192
https://doi.org/10.1158/1078-0432.22447695.v1
https://doi.org/10.1158/1078-0432.22447695.v1
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
Purpose: Glioblastoma (GBM), the most common primary brain tumor in adults, presents a high frequency of alteration in the PI3K pathway. Our objectives were to identify a dual PI3K/mTOR inhibitor optimized to cross the blood–brain barrier (BBB) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c07dac8b36b8db1529b9059f8f810bd
https://doi.org/10.1158/1078-0432.c.6521166.v1
https://doi.org/10.1158/1078-0432.c.6521166.v1
Autor:
Heidi S. Phillips, Alan G. Olivero, Stephen E. Gould, Xiaolin Zhang, Jeffrey J. Wallin, Jann N. Sarkaria, Hani Bou Reslan, Jenny L. Pokorny, Emile G. Plise, Jodie Pang, Leslie B. Lee, Shari Lau, Hartmut Koeppen, Samir Kharbanda, Joan Greve, Kyle A. Edgar, Jonathan Cheong, Richard A. Carano, Kai Barck, Merry Nishimura, Bruno Alicke, Timothy P. Heffron, Laurent Salphati
PDF file - 58K, Bioluminescence Analysis of U87 Intracranial Tumors in Mice at the Start of Treatment (Day 7 post-surgery) and at the End of Study (Day 28)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9bb3bd977bf22a37efaeedeeabc100
https://doi.org/10.1158/1078-0432.22447707.v1
https://doi.org/10.1158/1078-0432.22447707.v1
Autor:
Tejaswi, Worlikar, Mishal, Mendiratta-Lala, Eli, Vlaisavljevich, Ryan, Hubbard, Jiaqi, Shi, Timothy L, Hall, Clifford S, Cho, Fred T, Lee, Joan, Greve, Zhen, Xu
Publikováno v:
BME frontiers
Objective and Impact Statement. This is the first longitudinal study investigating the effects of histotripsy on local tumor progression in an in vivo orthotopic, immunocompetent rat hepatocellular carcinoma (HCC) model. Introduction. Histotripsy is