Výsledky vyhledávání - "Joan Galcerán"

Akademický článek

Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche

Autor: Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract The adult mammalian brain retains some capacity to replenish neurons and glia, holding promise for brain regeneration. Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial. Paradoxically, adu

Externí odkaz: https://doaj.org/article/4116623c87df4b3fb1ecede9d29f1a58

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Akademický článek

Publisher Correction: Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche

Autor: Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/5687f0b58b1a4ebfbe36976c0ac84aef

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Reply to: Zebrafish prrx1a mutants have normal hearts

Autor: Joan Galcerán, Aida Arcas, M. Angela Nieto, Noemi Castroviejo, Hakan Coskun, Luciano Rago, Oscar H. Ocaña

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Work in the laboratory is supported by grants from the Ministry of Science and Innovation through the Spanish State Research Agency (AEI) (MICIU RTI2018-096501-B-I00) and from Generalitat Valenciana (PROMETEOII/2017/150). M.A.N. also acknowledges the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d0a531ffb02e1bad6d39e26e624012
http://hdl.handle.net/10261/231178

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MicroRNAs establish the right-handed dominance of the heart laterality pathway in vertebrates

Autor: Francisco Garcia-Asencio, Hassan Fazilaty, Noemi Castroviejo, M. Angela Nieto, Luciano Rago, Joan Galcerán, Oscar H. Ocaña

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Despite their external bilateral symmetry, vertebrates have internal left/right (L/R) asymmetries required for optimal organ function. BMP-induced epithelial to mesenchymal transition (EMT) in the lateral plate mesoderm (LPM) triggers L/R asymmetric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6850d1d0e156bfd8111dd8f65931be26
http://hdl.handle.net/10261/217907

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A right-handed signalling pathway drives heart looping in vertebrates

Autor: Carolina Minguillón, Elly M. Tanaka, Oscar H. Ocaña, Joan Galcerán, Ramón Muñoz-Chápuli, Prayag Murawala, Hakan Coskun, M. Angela Nieto

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature
Digital.CSIC. Repositorio Institucional del CSIC
instname

Most animals show external bilateral symmetry, which hinders the observation of multiple internal left-right (L/R) asymmetries that are fundamental to organ packaging and function. In vertebrates, left identity is mediated by the left-specific Nodal-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966b1cf726401dd3586a760a38e0b473
http://hdl.handle.net/10261/155782

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Changes in liver and plasma acetylcholinesterase in rats with cirrhosis induced by bile duct ligation

Autor: Joan Galcerán, Asunción Candela, Miguel Pérez-Mateo, Joan Clària, M. Salud García-Ayllón, Rodrigo Jover, Javier Sáez-Valero, Vicente Felipo, Salvador Martinez, Antonio Compañ, M. Ximena Silveyra

Publikováno v: HEPATOLOGY
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
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r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Classical studies of cholinesterase activity during liver dysfunction have focused on butyrylcholinesterase (BuChE), whereas acetylcholinesterase (AChE) has not received much attention. In the current study, liver and plasma AChE levels were investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1db876fa6d6c15832a33b7661474393
https://doi.org/10.1002/hep.21071

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Acetylcholinesterase modulates presenilin-1 levels and γ-secretase activity

Autor: Joan Galcerán, Olivia Belbin, María Letizia Campanari, Javier Sáez-Valero, Alberto Lleó, María-Salud García-Ayllón

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

The cholinergic enzyme acetylcholinesterase (AChE) and the catalytic component of the ¿-secretase complex, presenilin-1 (PS1), are known to interact. In this study, we investigate the consequences of AChE-PS1 interactions, particularly the influence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c196ed0643b59b5f947a8ee78961cb1e
https://pubmed.ncbi.nlm.nih.gov/24699279

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Slit/Robo Signaling Modulates the Proliferation of Central Nervous System Progenitors

Autor: Gabriele Ciceri, Víctor Borrell, Oscar Marín, Nuria Flames, Ramón Pla, Le Ma, Joan Galcerán, Sandra Peregrín, Zhen Zhao, Sandrina Nóbrega-Pereira, Marc Tessier-Lavigne, Cristina García-Frigola, Adrián Cárdenas

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Neurogenesis relies on a delicate balance between progenitor maintenance and neuronal production. Progenitors divide symmetrically to increase the pool of dividing cells. Subsequently, they divide asymmetrically to self-renew and produce new neurons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d390dfe4744b28283292bf91130484
https://europepmc.org/articles/PMC4443924/

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Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth

Autor: Guillermina López-Bendito, Sonia Garel, Joan Galcerán, Erik Mire, Eduardo Leyva-Díaz, Marc Tessier-Lavigne, Cecilia Mezzera, Sandra Peregrín, Juan Lerma, Paola Squarzoni, Lisa Bluy, Ana V. Paternain, Mar Castillo-Paterna, María José López

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Developing axons must control their growth rate to follow the appropriate pathways and establish specific connections. However, the regulatory mechanisms involved remain elusive. By combining live imaging with transplantation studies in mice, we foun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9d1f092330c2482bf8926e5dcce9a3
http://hdl.handle.net/10261/71535

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Transcription at the ecdysone-inducible locus 2B5 inDrosophila

Autor: Olaf Pongs, Javier Sampedro, Marta Izquierdo, Javier Llanos, Joan Galcerán

Publikováno v: Nucleic Acids Research. 18:539-545

The Broad-Complex (BR-C) of D. melanogaster, mapping at the 2B5 early ecdysone puff, mediates ecdysone-induced processes. We present here the transcriptional analysis of the locus in both wild type and representative mutants. Two well defined regions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefe0d00ab21fe15694d2254207f407f
https://doi.org/10.1093/nar/18.3.539

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