Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Joan Galcerán"'
Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche
Autor:
Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The adult mammalian brain retains some capacity to replenish neurons and glia, holding promise for brain regeneration. Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial. Paradoxically, adu
Externí odkaz:
https://doaj.org/article/4116623c87df4b3fb1ecede9d29f1a58
Autor:
Ainara González-Iglesias, Aida Arcas, Ana Domingo-Muelas, Estefania Mancini, Joan Galcerán, Juan Valcárcel, Isabel Fariñas, M. Angela Nieto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5687f0b58b1a4ebfbe36976c0ac84aef
Autor:
Joan Galcerán, Aida Arcas, M. Angela Nieto, Noemi Castroviejo, Hakan Coskun, Luciano Rago, Oscar H. Ocaña
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Work in the laboratory is supported by grants from the Ministry of Science and Innovation through the Spanish State Research Agency (AEI) (MICIU RTI2018-096501-B-I00) and from Generalitat Valenciana (PROMETEOII/2017/150). M.A.N. also acknowledges the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d0a531ffb02e1bad6d39e26e624012
http://hdl.handle.net/10261/231178
http://hdl.handle.net/10261/231178
Autor:
Francisco Garcia-Asencio, Hassan Fazilaty, Noemi Castroviejo, M. Angela Nieto, Luciano Rago, Joan Galcerán, Oscar H. Ocaña
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Despite their external bilateral symmetry, vertebrates have internal left/right (L/R) asymmetries required for optimal organ function. BMP-induced epithelial to mesenchymal transition (EMT) in the lateral plate mesoderm (LPM) triggers L/R asymmetric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6850d1d0e156bfd8111dd8f65931be26
http://hdl.handle.net/10261/217907
http://hdl.handle.net/10261/217907
Autor:
Carolina Minguillón, Elly M. Tanaka, Oscar H. Ocaña, Joan Galcerán, Ramón Muñoz-Chápuli, Prayag Murawala, Hakan Coskun, M. Angela Nieto
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature
Digital.CSIC. Repositorio Institucional del CSIC
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Consejería de Sanidad de la Comunidad de Madrid
Nature
Digital.CSIC. Repositorio Institucional del CSIC
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Most animals show external bilateral symmetry, which hinders the observation of multiple internal left-right (L/R) asymmetries that are fundamental to organ packaging and function. In vertebrates, left identity is mediated by the left-specific Nodal-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966b1cf726401dd3586a760a38e0b473
http://hdl.handle.net/10261/155782
http://hdl.handle.net/10261/155782
Autor:
Joan Galcerán, Asunción Candela, Miguel Pérez-Mateo, Joan Clària, M. Salud García-Ayllón, Rodrigo Jover, Javier Sáez-Valero, Vicente Felipo, Salvador Martinez, Antonio Compañ, M. Ximena Silveyra
Publikováno v:
HEPATOLOGY
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Classical studies of cholinesterase activity during liver dysfunction have focused on butyrylcholinesterase (BuChE), whereas acetylcholinesterase (AChE) has not received much attention. In the current study, liver and plasma AChE levels were investig
Autor:
Joan Galcerán, Olivia Belbin, María Letizia Campanari, Javier Sáez-Valero, Alberto Lleó, María-Salud García-Ayllón
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The cholinergic enzyme acetylcholinesterase (AChE) and the catalytic component of the ¿-secretase complex, presenilin-1 (PS1), are known to interact. In this study, we investigate the consequences of AChE-PS1 interactions, particularly the influence
Autor:
Gabriele Ciceri, Víctor Borrell, Oscar Marín, Nuria Flames, Ramón Pla, Le Ma, Joan Galcerán, Sandra Peregrín, Zhen Zhao, Sandrina Nóbrega-Pereira, Marc Tessier-Lavigne, Cristina García-Frigola, Adrián Cárdenas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Neurogenesis relies on a delicate balance between progenitor maintenance and neuronal production. Progenitors divide symmetrically to increase the pool of dividing cells. Subsequently, they divide asymmetrically to self-renew and produce new neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d390dfe4744b28283292bf91130484
https://europepmc.org/articles/PMC4443924/
https://europepmc.org/articles/PMC4443924/
Autor:
Guillermina López-Bendito, Sonia Garel, Joan Galcerán, Erik Mire, Eduardo Leyva-Díaz, Marc Tessier-Lavigne, Cecilia Mezzera, Sandra Peregrín, Juan Lerma, Paola Squarzoni, Lisa Bluy, Ana V. Paternain, Mar Castillo-Paterna, María José López
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Developing axons must control their growth rate to follow the appropriate pathways and establish specific connections. However, the regulatory mechanisms involved remain elusive. By combining live imaging with transplantation studies in mice, we foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9d1f092330c2482bf8926e5dcce9a3
http://hdl.handle.net/10261/71535
http://hdl.handle.net/10261/71535
Publikováno v:
Nucleic Acids Research. 18:539-545
The Broad-Complex (BR-C) of D. melanogaster, mapping at the 2B5 early ecdysone puff, mediates ecdysone-induced processes. We present here the transcriptional analysis of the locus in both wild type and representative mutants. Two well defined regions