Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joan E. McEwen"'
Publikováno v:
Medical Mycology. 47:808-813
Histoplasma capsulatum is a primary fungal pathogen of mammals responsible for histoplasmosis. During pathogenesis H. capsulatum yeast proliferate in phagosomes of macrophages. This extensive host/pathogen interaction involves a complex cascade of re
Publikováno v:
Eukaryotic Cell. 3:835-846
The ability of a fungal pathogen to cause disease requires the ability to survive in the host. Survival in the host is dependent on evasion of the host's immune system, including the microbial killing mechanisms of phagocytes. The innate immune syste
Publikováno v:
Yeast. 20:381-388
Histoplasma capsulatum possesses a branched mitochondrial electron transport chain, with both cyanide-sensitive and -insensitive oxygen-consuming activities. The latter, carried out by a single subunit enzyme termed 'alternative oxidase', is the focu
Autor:
Clayton H. Johnson, Joan E. McEwen
Publikováno v:
Yeast. 15:799-804
A cDNA library was prepared from Histoplasma capsulatum strain G-217B yeast cells and an apparently full-length cDNA for a subunit of the citric acid cycle enzyme NAD(+)-isocitrate dehydrogenase was identified by sequence analysis. Its predicted amin
Publikováno v:
European Journal of Biochemistry. 255:156-161
The nuclear PET309 gene of Saccharomyces cerevisiae is necessary for expression of the mitochondrial COX1 gene, which encodes subunit I of cytochrome c oxidase. In a pet309 null mutant, there is a defect both in accumulation of COX1 pre-RNA, if it co
Publikováno v:
The Future of Aging ISBN: 9789048139989
Longevity variants in model systems such as nematodes or yeast provide an express route to discovery of pathways with the potential to greatly extend longevity. C. elegans in particular has provided an especially rich harvest of mutants and RNA-inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3846d8583bb160f49c70418206946682
https://doi.org/10.1007/978-90-481-3999-6_20
https://doi.org/10.1007/978-90-481-3999-6_20
Publikováno v:
Current opinion in cardiology. 20(5)
Purpose of review This review highlights common mechanisms of organismal aging and inflammatory coronary atherosclerosis. Recent findings A substantial body of evidence now indicates that aging is largely due to molecular damage inflicted by reactive
Autor:
Irina D. Pokrovskaya, Chunling Li, Dan Phan, Gouri Ranganathan, Philip A. Kern, Joan E. McEwen
Publikováno v:
The Journal of biological chemistry. 277(45)
The balance of lipid flux in adipocytes is controlled by the opposing actions of lipolysis and lipogenesis, which are controlled primarily by hormone-sensitive lipase and lipoprotein lipase (LPL), respectively. Catecholamines stimulate adipocyte lipo
Publikováno v:
Microbiology (Reading, England). 148(Pt 4)
Histoplasma capsulatum produces an extracellular catalase termed M antigen, which is similar to catalase B of Aspergillus and Emericella species. Evidence is presented here for two additional catalase isozymes in H. capsulatum. Catalase A is highly s
Autor:
Sudhir V. Marathe, Joan E. McEwen
Publikováno v:
Biochemistry and molecular biology international. 47(6)
The nuclear PET122 gene of S. cerevisiae encodes a mitochondrial-localized protein that activates initiation of translation of the mitochondrial mRNA from the COX3 gene, which encodes subunit III of cytochrome c oxidase. The PET122 locus contains two