Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joan E B, Fox"'
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13612 (2010)
Successful neovascularization requires that sprouting endothelial cells (ECs) integrate to form new vascular networks. However, architecturally defective, poorly integrated vessels with blind ends are typical of pathological angiogenesis induced by v
Externí odkaz:
https://doaj.org/article/7b946be970d04e1892ebddab96a2ac41
Autor:
Nataly P. Podolnikova, Stephen C.-T. Lam, Tatiana P. Ugarova, Thomas A. Haas, Joan E. B. Fox, Timothy O'Toole
Publikováno v:
Biochemistry. 48:617-629
Integrin αIIbβ3 plays a pivotal role in hemostasis and thrombosis by mediating adhesive interactions of platelets. Binding of αIIbβ3 to its physiological ligands, immobilized fibrinogen and fibrin,...
Autor:
Lorraine Lipfert, Cary D. Austin, Joan E. B. Fox, Joan S. Brugge, Edwin A. Clark, Clifford C. Reynolds
Publikováno v:
Journal of Biological Chemistry. 268:25973-25984
The platelet plasma membrane is lined with a membrane skeleton composed of short actin filaments, actin-binding protein, spectrin, vinculin, and other unidentified proteins. It is connected to the outside of the cell through association with the cyto
Autor:
Joan E. B. Fox
Publikováno v:
Thrombosis and Haemostasis. 70:0884-0893
SummaryThe platelet cytoskeleton contains two actin filament-based components. One is the cytoplasmic actin filaments which fill the cytoplasm and mediate contractile events. The other is the membrane skeleton, which coats the plasma membrane and reg
Autor:
Susan E. Rittenhouse, Lan Liao, Michael J. Fry, Michael D. Waterfield, Susan Jaken, Jin Zhang, Joan E B Fox
Publikováno v:
Journal of Biological Chemistry. 267:4686-4692
Human platelets undergo a rapid, major reorganization of the cytoskeletal matrix upon exposure to thrombin, and accumulate 3-phosphorylated phosphoinositides in a protein kinase C (PKC)-dependent manner. These phosphoinositides have been suggested to
Autor:
Nataly P, Podolnikova, Timothy E, O'Toole, Thomas A, Haas, Stephen C-T, Lam, Joan E B, Fox, Tatiana P, Ugarova
Publikováno v:
Biochemistry. 48(3)
Integrin alpha(IIb)beta(3) plays a pivotal role in hemostasis and thrombosis by mediating adhesive interactions of platelets. Binding of alpha(IIb)beta(3) to its physiological ligands, immobilized fibrinogen and fibrin, induces outside-in signaling i
Publikováno v:
The Journal of biological chemistry. 278(35)
Integrin-induced cytoskeletal reorganizations are initiated by Cdc42 and Rac1 but little is known about mechanisms by which integrins activate these Rho GTPases. 14-3-3 proteins are adaptors implicated in binding and regulating the function and subce
Autor:
Richard C, Austin, Joan E B, Fox, Geoff H, Werstuck, Alan R, Stafford, Dennis E, Bulman, Ghassan Y, Dally, Cameron A, Ackerley, Jeffrey I, Weitz, Peter N, Ray
Publikováno v:
The Journal of biological chemistry. 277(49)
Utrophin is a component of the platelet membrane cytoskeleton and participates in cytoskeletal reorganization (Earnest, J. P., Santos, G. F., Zuerbig, S., and Fox, J. E. B. (1995) J. Biol. Chem. 270, 27259-27265). Although platelets do not contain dy
Autor:
Katarzyna, Bialkowska, Joan E B, Fox
Publikováno v:
Cellularmolecular biology letters. 6(2)
Autor:
Joan E. B. Fox
Publikováno v:
Annals of the New York Academy of Sciences. 714
The platelet membrane is lined by a membrane skeleton, which in turn appears to be associated with underlying cytoplasmic actin filaments. Glycoprotein IIb-IIIa appears to associate with the membrane skeleton in unstimulated platelets. Upon platelet