Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Joan E, Hilner"'
Autor:
Mark A, Pereira, David R, Jacobs, Martha L, Slattery, Karen J, Ruth, Linda, Van Horn, Joan E, Hilner, Lawrence H, Kushi
Publikováno v:
CVD prevention : the journal of the International Society and Federation of Cardiology. 1(3)
Whole grain consumption may influence insulin through beneficial effects on satiety and body weight, intestinal absorption, or the action of specific nutrients or constituents.We examined the associations of whole grain intake, assessed by a diet his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::741f64559945e5044d945cf2c53eea9f
https://pubmed.ncbi.nlm.nih.gov/30636864
https://pubmed.ncbi.nlm.nih.gov/30636864
Publikováno v:
Diabetes Care
The Type 1 Diabetes Genetics Consortium (T1DGC) comprised groups of investigators from many countries throughout the world, with a common goal of identifying genes predisposing to type 1 diabetes. The T1DGC ascertained and collected samples from fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f57310e81d69c39a18e8129836d6ce
http://europepmc.org/articles/PMC4582913
http://europepmc.org/articles/PMC4582913
Autor:
Concepcion Nierras, Munish Mehta, Cécile Julier, Ian James, Jørn Nerup, Grant Morahan, Joan E. Hilner, Stephen S. Rich, Flemming Pociot, Wei-Min Chen, Beena Akolkar, John A. Todd, Henry A. Erlich
Publikováno v:
Diabetes. 60:1030-1040
OBJECTIVE Interactions between genetic and environmental factors lead to immune dysregulation causing type 1 diabetes and other autoimmune disorders. Recently, many common genetic variants have been associated with type 1 diabetes risk, but each has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffaa74023edb672af1e39ee84d3439f8
https://doi.org/10.2337/db10-1195
https://doi.org/10.2337/db10-1195
Autor:
Shane A. Gellert, Alistair J K Williams, Polly J. Bingley, June J Pierce, Beena Akolkar, George S. Eisenbarth, T Dgc, Michael W. Steffes, Peter G. Colman, Letitia H Perdue, Joan E. Hilner, Concepcion Nierras, Liping Yu
Publikováno v:
Clinical Trials (London, England)
Background and Purpose Three network laboratories measured antibodies to islet autoantigens. Antibodies to glutamic acid decarboxylase (GAD65 [GADA]) and the intracellular portion of protein tyrosine phosphatase (IA-2ic [IA-2A]) were measured by simi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b64714b338a166b821be9ccec6ef17
https://doi.org/10.1177/1740774510373496
https://doi.org/10.1177/1740774510373496
Autor:
Beena Akolkar, Catherine McKeon, Joan E. Hilner, Mark A. Hall, Nancy M. P. King, T Dgc, Carla J. Greenbaum, Letitia H Perdue
Publikováno v:
Clinical Trials (London, England)
Background and Purpose This article describes several ethical, legal, and social issues typical of international genetics biobanking, as encountered in the Type 1 Diabetes Genetics Consortium (T1DGC). Methods By studying the examples set and lessons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1c082d36089d59f6eb69ac90719363
https://doi.org/10.1177/1740774510373492
https://doi.org/10.1177/1740774510373492
Autor:
Ana M Wägner, Lotte Albret, Michael W. Steffes, Alan Aldrich, Amanda Loth, Joan E. Hilner, Letitia H Perdue, Rebecca Waterman, Angela Dove, T Dgc, June J Pierce, Beena Akolkar, Elizabeth G. Sides
Publikováno v:
Clinical Trials (London, England)
Background When collecting phenotypic data in clinics across the globe, the Type 1 Diabetes Genetics Consortium (T1DGC) used several techniques that ensured consistency, completeness, and accuracy of the data. Purpose The aim of this article is to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6ef7c631911276ea3de0122141e6b0
https://doi.org/10.1177/1740774510373495
https://doi.org/10.1177/1740774510373495
Autor:
Gary J. Olsem, Sarah Nutland, June J Pierce, Ian Nicholson, Michael W. Steffes, Joan E. Hilner, Letitia H Perdue, Michael D. Varney, Beena Akolkar, Silke Rosinger, John A. Hansen, Bernard O Boehm, T Dgc, Eric Mickelson, Concepcion Nierras
Publikováno v:
Clinical Trials (London, England)
Background and Purpose To yield large amounts of DNA for many genotype analyses and to provide a renewable source of DNA, the Type 1 Diabetes Genetics Consortium (T1DGC) harvested DNA and peripheral blood mononuclear cells (PBMCs) from individuals wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece286f10e91ddf4413ce2bd8c4057df
https://doi.org/10.1177/1740774510373493
https://doi.org/10.1177/1740774510373493
Autor:
June J Pierce, David M. Reboussin, Letitia H Perdue, Anthony Louey, Julie A. Lane, Jeff Post, Sean Boyle, Dustin T. Williams, Joan E. Hilner, Beena Akolkar, Michael D. Varney, Wolfgang Helmberg, P. V. Moonsamy, Persia Bonella, Rebecca Rappner, Janelle A. Noble, Henry A. Erlich, Josyf C. Mychaleckyj, Paul Sali, Eva Lavant, Samuel Kim, T Dgc, Michael W. Steffes, Anna Lisa Fear, Joyce Carlson, Brian D. Tait
Publikováno v:
Clinical Trials (London, England)
Background Although human leukocyte antigen (HLA) DQ and DR loci appear to confer the strongest genetic risk for type 1 diabetes, more detailed information is required for other loci within the HLA region to understand causality and stratify addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ff1837968868e3aba994243e5d479f
https://doi.org/10.1177/1740774510373494
https://doi.org/10.1177/1740774510373494
Autor:
John A. Todd, Flemming Pociot, J Nerup, Beena Akolkar, Grant Morahan, Stephen S. Rich, Joan E. Hilner, Cécile Julier, Patrick Concannon, Concepcion Nierras, Henry A. Erlich
Publikováno v:
Genes & Immunity. 10:S128-S131
The Type I Diabetes Genetics Consortium (T1DGC) is an international collaboration whose primary goal is to identify genes whose variants modify an individual's risk of type I diabetes (T1D). An integral part of the T1DGC's mission is the establishmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c5e4cb9370f152c5389b00dfd5ecc5
https://doi.org/10.1038/gene.2009.100
https://doi.org/10.1038/gene.2009.100
Autor:
Joan E. Hilner, Stephen S. Rich, Cécile Julier, John A. Todd, Patrick Concannon, Jørn Nerup, Henry A. Erlich, Concepcion Nierras, Flemming Pociot, Beena Akolkar, Wei-Min Chen, Grant Morahan
Publikováno v:
Diabetes
OBJECTIVE Type 1 diabetes arises from the actions of multiple genetic and environmental risk factors. Considerable success at identifying common genetic variants that contribute to type 1 diabetes risk has come from genetic association (primarily cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f783e6cb9aaf87f5c02bde39208ac860
https://doi.org/10.2337/db08-1551
https://doi.org/10.2337/db08-1551