Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joan Duignan"'
Autor:
Steve Finegan, Jennifer L. Liras, John Schafer, Gregory G. Stone, Sarah K. Wade, Ann G. Connolly, Rhonda Monahan, Katherine E. Brighty, Joan Duignan, Steven J. Brickner, Phuong Le, Ivan J. Samardjiev, Richard P. Zaniewski, Dennis Girard, Jon Bordner, Meghan Maloney
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:276-279
SAR studies and optimization of various modified Hygromycin A fluoroalkyl ethers, which led to the discovery of the highly potent 4'-(2-cyclopropyl-2-fluoroethyl ether) antibacterial CE-156811 (1) derived from truncation of the ribose ring and difluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31058e211b4e5cd78b92b592ecef72f
https://doi.org/10.1016/j.bmcl.2010.11.022
https://doi.org/10.1016/j.bmcl.2010.11.022
Autor:
Joyce A. Sutcliffe, Yutaka Sugie, Koen A. Dekker, Yoon-Jeong Kim, Joan Duignan, Lori Brennan, Shinichi Sakemi, Akemi Sugiura, Yasuhiro Kojima, Taisuke Inagaki, Tatsuo Sakakibara
Publikováno v:
The Journal of Antibiotics. 55:19-24
A new antibiotic, CJ-17,572 (I) was isolated from the fermentation broth of a fungus Pezicula sp. CL11877. The structure of I was determined to be a new equisetin derivative by spectroscopic analyses. The compound inhibits the growth of multi-drug re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8b983b7798266d7d6c17e4edefff56
https://doi.org/10.7164/antibiotics.55.19
https://doi.org/10.7164/antibiotics.55.19
Autor:
Lori Brennan, Joan Duignan, Yoon-Jeong Kim, Joyce A. Sutcliffe, Akemi Sugiura, Taisuke Inagaki, Yasuhiro Kojima, Shinichi Sakemi, Nakao Kojima, Yumiko Suzuki, Hideo Hirai, Masaru Ishiguro, Yutaka Sugie, Liang Hsiung Huang, Tatsuo Sakakibara
Publikováno v:
The Journal of Antibiotics. 54:911-916
A new antibiotic, CJ-17,665 (I) was isolated from the fermentation broth of Aspergillus ochraceus, CL41582. It inhibits growth of multi-drug resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db1d9eb14358485f2152b67f17ce456
https://doi.org/10.7164/antibiotics.54.911
https://doi.org/10.7164/antibiotics.54.911
Autor:
Barbara J, Kamicker, Michael T, Sweeney, Frank, Kaczmarek, Fadia, Dib-Hajj, Wenchi, Shang, Kim, Crimin, Joan, Duignan, Thomas D, Gootz
Publikováno v:
Methods in molecular medicine. 142
Infections caused by multidrug-resistant Gram-negative pathogens play a major role in the morbidity and mortality of hospitalized patients. The rise of resistance to current antibiotic therapies has made the discovery of new agents urgent. One of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47406ad0f1eee348106dbd3e57902c43
https://pubmed.ncbi.nlm.nih.gov/18437315
https://pubmed.ncbi.nlm.nih.gov/18437315
Autor:
Meghan Maloney, Steve Finegan, Dennis Girard, Gregory G. Stone, John Schafer, Sarah K. Wade, Phuong Le, Steven J. Brickner, Michael D. Huband, Joan Duignan, Richard P. Zaniewski
Publikováno v:
Antimicrobial agents and chemotherapy. 52(7)
We evaluated a novel truncated hygromycin A analog in which the furanose ring was replaced with a 2-fluoro-2-cyclopropylethyl substituent for its activity against multidrug resistant gram-positive bacteria and compared its activity to the activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54257226f2409edddbf8487000e85f25
https://pubmed.ncbi.nlm.nih.gov/18426902
https://pubmed.ncbi.nlm.nih.gov/18426902
Autor:
Wenchi Shang, Frank S. Kaczmarek, Michael T. Sweeney, Thomas D. Gootz, Fadia Dib-Haj, Joan Duignan, Kim Crimin, Barbara J. Kamicker
Publikováno v:
Methods In Molecular Medicine™ ISBN: 9781588299154
Infections caused by multidrug-resistant Gram-negative pathogens play a major role in the morbidity and mortality of hospitalized patients. The rise of resistance to current antibiotic therapies has made the discovery of new agents urgent. One of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6aed440d023c7b37ff43bf79a17d51
https://doi.org/10.1007/978-1-59745-246-5_15
https://doi.org/10.1007/978-1-59745-246-5_15
Autor:
Joyce A. Sutcliffe, Joan Duignan, Hideo Hirai, Lori Brennan, Liang Hsiung Huang, Yukio Shioni, Masaru Ishiguro, Koen A. Dekker, Toshio Ichiba, Akemi Sugiura, Yasuhiro Kojima, Yutaka Sugie
Publikováno v:
The Journal of antibiotics. 54(12)
A novel antibiotic, CJ-15,801 (I), was isolated from the fermentation broth of a fungus, Seimatosporium sp. CL28611. The structure was determined to be a pantothenic acid analog having an alpha,beta-unsaturated carboxylic acid moiety by spectroscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36db9200c15da5ef265e79c82f085cb
https://pubmed.ncbi.nlm.nih.gov/11858661
https://pubmed.ncbi.nlm.nih.gov/11858661
Autor:
Hideo Hirai, Ayumu Sugiura, Nakao Kojima, Yutaka Sugie, Nobuji Yqshikawa, Joan Duignan, Yukio Shiomi, Joyce A. Sutcliffe, Yoon-Jeong Kim, Liang Hsiung Huang, Akemi Sugiura, Yasuhiro Kojima, Lori Brennan, Yumiko Suzuki, Hiroko Kachi-Tonai
Publikováno v:
The Journal of antibiotics. 54(11)
Two new antibiotics, CJ-16,264 (I) and CJ-16,367 (II), were isolated from the fermentation broth of an unidentified fungus CL39457. These antibiotics have a pyrrolizidinone skeleton, first discovered in fungi. Compounds I and II inhibit the growth of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f49b8411319ca62acd39bf55fa1ad2
https://pubmed.ncbi.nlm.nih.gov/11827034
https://pubmed.ncbi.nlm.nih.gov/11827034