Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joan D. Glass"'
Autor:
Joan D. Glass, Elizabeth P. Baskin, Halea A. Hartman, Jacquelynn J. Cook, James C. Hershey, Irene T. Rogers, David B. Gilberto
Publikováno v:
Cardiovascular Research. 49:618-625
Objective: Animal models of hindlimb ischemia are critical to our understanding of peripheral vascular disease and allow us to evaluate therapeutic strategies aimed to improve peripheral collateral circulation. To further elucidate the processes invo
Autor:
Adel M. Naylor-Olsen, Jacquelynn J. Cook, Robert J. Meissner, Amy E. Zartman, William F. Hoffman, Robert J. Gould, Guixiang Zhang, George D. Hartman, Joan D. Glass, R. J. Lynch, Mark E. Duggan, James J. Perkins
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:863-868
A new series of potent, linearly-minimized, orally active, selective GPIIb/IIIa inhibitors is identified. Thus 15 (L-750,034) achieves interaction via a constrained, non-turned conformation that maintains the proper distance between its charged termi
Publikováno v:
The Journal of Immunology. 161:5321-5330
To investigate mechanisms of cell-mediated events in chronic glomerulonephritis, T cell clones were isolated from kidneys of animals with murine chronic graft-vs-host disease. This systemic disorder is induced in normal (C57BL/6 × DBA/2)F1 recipient
Autor:
B. C. Askew, Thomayant Prueksaritanont, Joseph J. Lynch, Charles J. Mcintyre, Terrence G. Hamill, Rodney A. Bednar, Marie A. Holahan, Stanley L. Gaul, R. J. Lynch, G. R. Sitko, Robert J. Gould, Joan D. Glass, Cecila A. Hunt, John J. Baldwin, Jacquelynn J. Cook, Lynn M. Gorham, George D. Hartman, David A. Claremon, Maria T. Stranieri, Bohumil Bednar
Publikováno v:
Journal of Medicinal Chemistry. 40:1779-1788
The synthesis and pharmacological evaluation of 5 (L-738, 167), a potent, selective non-peptide fibrinogen receptor antagonist is reported. Compound 5 inhibited the aggregation of human gel-filtered platelets with an IC50 value of 8 nM and was found
Autor:
Maria T. Stranieri, Wasyl Halczenko, R. J. Lynch, George D. Hartman, Joan D. Glass, John H. Hutchinson, Michael J. Breslin, G. R. Sitko, Marie A. Holahan, Robert J. Gould, Jacquelynn J. Cook, Karen M. Brashear
Publikováno v:
Journal of Medicinal Chemistry. 39:4583-4591
The structure-activity relationship of a series of orally active glycoprotein IIb/IIIa antagonists containing a nitrogen heterocycle grafted onto a 3,4-dihydro-1 (1H)-isoquinolinone core is described. These compounds are structurally novel analogs of
Autor:
Karen M. Brashear, Maria T. Stranieri, G. R. Sitko, Robert J. Gould, Marie A. Holahan, Michael J. Breslin, Joan D. Glass, Jacquelynn J. Cook, R. J. Lynch, Wasyl Halczenko, John H. Hutchinson, George D. Hartman
Publikováno v:
ChemInform. 28