Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Joan D. Beckman"'
Autor:
Amelia G. Campbell, Davis M. Seelig, Joan D. Beckman, Katie M. Minor, Daniel A. Heinrich, Steven G. Friedenberg, Jaime F. Modiano, Eva Furrow
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 4, Pp 1237-1247 (2022)
Abstract Background Myelofibrosis often lacks an identifiable cause in dogs. In humans, most primary myelofibrosis cases develop secondary to driver mutations in JAK2, CALR, or MPL. Objectives To determine the prevalence of variants in JAK2, CALR, or
Externí odkaz:
https://doaj.org/article/a7315aa5647f45fa93563d64851d9eb2
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Hereditary Hemorrhagic Telangiectasia (HHT) is a rare inherited disorder characterized by development of mucocutaneous telangiectases and visceral organ arteriovenous malformations, which can lead to recurrent, spontaneous bleedin
Externí odkaz:
https://doaj.org/article/4645b62ceb4a4cd3815dd99321cb6651
Autor:
Aaron R. Folsom, Wendy Wang, Romil Parikh, Pamela L. Lutsey, Joan D. Beckman, Mary Cushman, for the Atherosclerosis Risk in Communities (ARIC) Study Investigators
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 3, Pp 422-428 (2020)
Abstract Background Patients with polycythemia vera with high hematocrit have increased risk of venous thromboembolism (VTE). Objective To determine whether high hematocrit in the general population is also associated with elevated VTE risk. Methods
Externí odkaz:
https://doaj.org/article/82254aa229bf4faca595489fe7d6b368
Autor:
Joan D. Beckman, Angelica DaSilva, Elena Aronovich, Aithanh Nguyen, Julia Nguyen, Geneva Hargis, David Reynolds, Gregory M. Vercellotti, Brian Betts, David K. Wood
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1366-1380
Autor:
Ping Zhang, Julia Nguyen, Fuad Abdulla, Alexander T. Nelson, Joan D. Beckman, Gregory M. Vercellotti, John D. Belcher
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recent evidence indicates that hemolysis in sickle cell disease (SCD) promotes inflammation via innate immune signaling through toll-like receptor 4 (TLR4). Free heme released by hemolyzed red blood cells can bind to myeloid differentiation factor-2
Externí odkaz:
https://doaj.org/article/8097497790ab421091767ee13d2b3a35
Autor:
Joan D. Beckman, Fuad Abdullah, Chunsheng Chen, Rachel Kirchner, Dormarie Rivera-Rodriguez, Zachary M. Kiser, Aithanh Nguyen, Ping Zhang, Julia Nguyen, Robert P. Hebbel, John D. Belcher, Gregory M. Vercellotti
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Heme, released from red blood cells in sickle cell disease (SCD), interacts with toll-like receptor 4 (TLR4) to activate NF-κB leading to the production of cytokines and adhesion molecules which promote inflammation, pain, and vaso-occlusion. In SCD
Externí odkaz:
https://doaj.org/article/8b85be8fe59f4192a1fe566fbb2c75ec
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 1, Iss , Pp 100002- (2020)
Background: Cancer is a leading cause of provoked venous thromboembolism (VTE) and requires use of anticoagulation. As the incidence of lobular breast carcinoma increases, more breast cancer patients experience gastrointestinal metastatic disease whi
Externí odkaz:
https://doaj.org/article/c3167983c333469197b8a5bd07fb9943
Publikováno v:
Translational Research. 246:1-14
Sickle cell disease (SCD) is caused by a single point mutation in the β-globin gene of hemoglobin, which produces an altered sickle hemoglobin (HbS). The ability of HbS to polymerize under deoxygenated conditions gives rise to chronic hemolysis, oxi
Autor:
Aithanh Nguyen, Joseph P Juliette, Alison Wong, Elena Aronovich, Maya Abdullah, Julia Nguyen, Fuad Abdulla, Chunsheng Chen, Iryna A Khasabova, John D Belcher, Gregory M. Vercellotti, Donald Simone, Joan D Beckman
Publikováno v:
Blood. 140:2500-2501
Autor:
Douglas Tremblay, Adam Winters, Joan D. Beckman, Leonard Naymagon, Rahul Patel, John Mascarenhas, Thomas D. Schiano
Publikováno v:
Thrombosis research. 218
Splanchnic vein thrombosis (SVT) in the setting of myeloproliferative neoplasm (MPN) is a unique clinical entity that requires close interdisciplinary coordination for proper diagnosis and management. The pathobiology of MPN-SVT is not fully understo