Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joan Castellsague"'
Autor:
Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B. Huppa, Sonia Guedan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Chimeric antigen receptor (CAR)-T cell therapy for solid tumors faces significant hurdles, including T-cell inhibition mediated by the PD-1/PD-L1 axis. The effects of disrupting this pathway on T-cells are being actively explored and controv
Externí odkaz:
https://doaj.org/article/7804df0598d54b5bb293efc2b4f633cf
Autor:
Joan Maria Viñals, August Vidal, Alberto Villanueva, Ignacio Blanco, Gabriel Capellá, Ernest Terribas, Rafael Valdés-Mas, Adriana Lopez-Doriga, Javier García-del Muro, Joan Castellsague, Xose S. Puente, Bernat Gel, Conxi Lázaro, Yolanda Benavente, Roger Llatjós, Diana Pérez-Sidelnikova, Miguel Angel Pujana, Eduard Serra, Juana Fernández-Rodríguez
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
ResearcherID
Recercat. Dipósit de la Recerca de Catalunya
instname
EMBO Molecular Medicine
Dipòsit Digital de la UB
Universidad de Barcelona
Universitat Autònoma de Barcelona
ResearcherID
Recercat. Dipósit de la Recerca de Catalunya
instname
EMBO Molecular Medicine
Dipòsit Digital de la UB
Universidad de Barcelona
Malignant peripheral nerve sheath tumors (MPNSTs) are soft-tissue sarcomas that can arise either sporadically or in association with neurofibromatosis type 1 (NF1). These aggressive malignancies confer poor survival, with no effective therapy availab
Autor:
Antonio Russi, Mark Nellist, Conxi Lázaro, Joan Castellsague, Jihong Jiang, Christopher A. Maxwell, Nadia García, Helen Chen, Miguel Angel Pujana, Isidre Ferrer, Israel Ampuero, Laia Gómez-Baldó, Helena Aguilar, Pooja Mohan, Marga Carmona, Margaretha A. Skowron
Publikováno v:
The Journal of Pathology. 233:247-257
Most patients with tuberous sclerosis complex (TSC) develop cortical tubers that cause severe neurological disabilities. It has been suggested that defects in neuronal differentiation and/or migration underlie the appearance of tubers. However, the p
Autor:
Oksana Nemirovsky, Conxi Lázaro, Melanie Spyra, Kristi Allen, Lan Kluwe, Jonathan J Keats, Joan Castellsague, Christopher A. Maxwell, Alberto Villanueva, Sandra E. Dunn, Miguel Angel Pujana, Jihong Jiang, Kaiji Hu, Victor F. Mautner, Helen Chen, Pooja Mohan
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Oncotarget
ResearcherID
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Oncotarget
ResearcherID
Malignant peripheral nerve sheath tumours (MPNST) are rare, hereditary cancers associated with neurofibromatosis type I. MPNSTs lack effective treatment options as they often resist chemotherapies and have high rates of disease recurrence. Aurora kin
Autor:
Isidre, Ferrer, Pooja, Mohan, Helen, Chen, Joan, Castellsague, Laia, Gómez-Baldó, Marga, Carmona, Nadia, García, Helena, Aguilar, Jihong, Jiang, Margaretha, Skowron, Mark, Nellist, Israel, Ampuero, Antonio, Russi, Conxi, Lázaro, Christopher A, Maxwell, Miguel Angel, Pujana
Publikováno v:
The Journal of pathology. 233(3)
Most patients with tuberous sclerosis complex (TSC) develop cortical tubers that cause severe neurological disabilities. It has been suggested that defects in neuronal differentiation and/or migration underlie the appearance of tubers. However, the p
Autor:
Yolanda Benavente, Ignacio Blanco, Conxi Lázaro, Joan Castellsague, Llúcia Benito, Eduard Serra, Gabriel Capellá, Juana Fernández-Rodríguez
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Here we analyze the genetic and molecular basis responsible for a very benign phenotype observed in an NF1 patient. Quantification of cells carrying the NF1 mutation in different samples derived from the three embryonic layers revealed mosaicism. Fur
Autor:
Helen Chen, Lan Kluwe, Kaiji Hu, Joan Castellsague, Jihong Jiang, Oksana Nemirovsky, Sandra E. Dunn, Kristi Allen, Jonathan J Keats, Miguel Angel Pujana, Christopher A. Maxwell, Conxi Lázaro, Melanie Spyra, Alberto Villanueva, Pooja Mohan, Victor F. Mautner
Publikováno v:
Cancer Research. 73:LB-214
Malignant peripheral nerve sheath tumours (MPNST) are rare, hereditary, cancers associated with mutations in the neurofibromin 1 gene 1. MPNSTs are often resistant to chemotherapies and have high rates of disease recurrence, highlighting the lack of
Autor:
Christopher A Maxwell, Javier Benítez, Laia Gómez-Baldó, Ana Osorio, Núria Bonifaci, Ricardo Fernández-Ramires, Sylvain V Costes, Elisabet Guinó, Helen Chen, Gareth J R Evans, Pooja Mohan, Isabel Català, Anna Petit, Helena Aguilar, Alberto Villanueva, Alvaro Aytes, Jordi Serra-Musach, Gad Rennert, Flavio Lejbkowicz, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Carla B Ripamonti, Bernardo Bonanni, Alessandra Viel, Anna Allavena, Loris Bernard, Paolo Radice, Eitan Friedman, Bella Kaufman, Yael Laitman, Maya Dubrovsky, Roni Milgrom, Anna Jakubowska, Cezary Cybulski, Bohdan Gorski, Katarzyna Jaworska, Katarzyna Durda, Grzegorz Sukiennicki, Jan Lubiński, Yin Yao Shugart, Susan M Domchek, Richard Letrero, Barbara L Weber, Frans B L Hogervorst, Matti A Rookus, J Margriet Collee, Peter Devilee, Marjolijn J Ligtenberg, Rob B van der Luijt, Cora M Aalfs, Quinten Waisfisz, Juul Wijnen, Cornelis E P van Roozendaal, HEBON, EMBRACE, Douglas F Easton, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Patricia Harrington, D Gareth Evans, Fiona Lalloo, Rosalind Eeles, Louise Izatt, Carol Chu, Diana Eccles, Fiona Douglas, Carole Brewer, Heli Nevanlinna, Tuomas Heikkinen, Fergus J Couch, Noralane M Lindor, Xianshu Wang, Andrew K Godwin, Maria A Caligo, Grazia Lombardi, Niklas Loman, Per Karlsson, Hans Ehrencrona, Anna von Wachenfeldt, SWE-BRCA, Rosa Bjork Barkardottir, Ute Hamann, Muhammad U Rashid, Adriana Lasa, Trinidad Caldés, Raquel Andrés, Michael Schmitt, Volker Assmann, Kristen Stevens, Kenneth Offit, João Curado, Hagen Tilgner, Roderic Guigó, Gemma Aiza, Joan Brunet, Joan Castellsagué, Griselda Martrat, Ander Urruticoechea, Ignacio Blanco, Laima Tihomirova, David E Goldgar, Saundra Buys, Esther M John, Alexander Miron, Melissa Southey, Mary B Daly, BCFR, Rita K Schmutzler, Barbara Wappenschmidt, Alfons Meindl, Norbert Arnold, Helmut Deissler, Raymonda Varon-Mateeva, Christian Sutter, Dieter Niederacher, Evgeny Imyamitov, Olga M Sinilnikova, Dominique Stoppa-Lyonne, Sylvie Mazoyer, Carole Verny-Pierre, Laurent Castera, Antoine de Pauw, Yves-Jean Bignon, Nancy Uhrhammer, Jean-Philippe Peyrat, Philippe Vennin, Sandra Fert Ferrer, Marie-Agnès Collonge-Rame, Isabelle Mortemousque, GEMO Study Collaborators, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, Sue Healey, kConFab, Mary Helen Barcellos-Hoff, Marc Vidal, Stephen B Gruber, Conxi Lázaro, Gabriel Capellá, Lesley McGuffog, Katherine L Nathanson, Antonis C Antoniou, Georgia Chenevix-Trench, Markus C Fleisch, Víctor Moreno, Miguel Angel Pujana
Publikováno v:
PLoS Biology, Vol 9, Iss 11, p e1001199 (2011)
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal breast tissue and increased ri
Externí odkaz:
https://doaj.org/article/6b575e23a5b6401b9e491335b8001395