Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joan Blanco-Fernandez"'
Autor:
Carme Arnan, Sebastian Ullrich, Carlos Pulido-Quetglas, Ramil Nurtdinov, Alexandre Esteban, Joan Blanco-Fernandez, Estel Aparicio-Prat, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract CRISPR-Cas9 screening libraries have arisen as a powerful tool to identify protein-coding (pc) and non-coding genes playing a role along different processes. In particular, the usage of a nuclease active Cas9 coupled to a single gRNA has pro
Externí odkaz:
https://doaj.org/article/4c100e2cafc94ba2aca5955791116310
Publikováno v:
Methods in Molecular Biology, vol. 2661, pp. 329-342
Methods in Molecular Biology ISBN: 9781071631706
Methods in Molecular Biology ISBN: 9781071631706
Pooled genetic screens have revolutionized the field of functional genomics, yet perturbations that decrease fitness, such as those leading to synthetic lethality, have remained difficult to quantify at the genomic level. We and colleagues previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cedc086757a8dec35ae6003edf5dda8
https://serval.unil.ch/resource/serval:BIB_F76D5A9A3A60.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_F76D5A9A3A60.P001/REF.pdf
Autor:
Valentin Barquissau, Nadège Zanou, Sarah Geller, Judit Castillo-Armengol, Flavia Marzetta, Katharina Huber, Dorian Ziegler, Isabel Lopez-Mejia, Joan Blanco Fernandez, Catherine Roger, Nicolas Guex, Frédéric Preitner, Jean-Marc Vanacker, Lluis Fajas
Cyclin-dependent kinase 4 (CDK4) canonical role is to control cell cycle progression from G1 to S phases. However, recent studies reported that CDK4 regulates energy metabolism in non-proliferating cells such as hepatocytes or adipocytes. The objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94639281f009758fc162a0fc7c028729
https://doi.org/10.1101/2022.03.03.482783
https://doi.org/10.1101/2022.03.03.482783
Autor:
Roderic Guigó, Alexandre Esteban, Carlos Pulido-Quetglas, Carme Arnan, Joan Blanco-Fernandez, Sebastian Ullrich, Sílvia Pérez-Lluch, Estel Aparicio-Prat, Rory Johnson, Ramil N. Nurtdinov
Publikováno v:
Arnan, Carme; Ullrich, Sebastian; Pulido-Quetglas, Carlos; Nurtdinov, Ramil; Esteban, Alexandre; Blanco-Fernandez, Joan; Aparicio-Prat, Estel; Johnson, Rory; Pérez-Lluch, Sílvia; Guigó, Roderic (2022). Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages. BMC Genomics, 23(1), p. 402. BioMed Central 10.1186/s12864-022-08612-7
CRISPR-Cas9 screening libraries have arisen as a powerful tool to identify protein-coding (pc) and non-coding genes playing a role along different processes. In particular, the usage of a nuclease active Cas9 coupled to a single gRNA has proven to ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fced87456a3125c78ee1e7f405bf774
https://pubmed.ncbi.nlm.nih.gov/35619054
https://pubmed.ncbi.nlm.nih.gov/35619054