Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Joan Blanchette"'
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 214-225 (2000)
Combined lipase deficiency (cld) is a recessive mutation in mice that causes a severe lack of lipoprotein lipase (LPL) and hepatic lipase (HL) activities, hyperlipemia, and death within 3 days after birth. Earlier studies showed that inactive LPL and
Externí odkaz:
https://doaj.org/article/9bb567761e0d4c74a9be92c39ceae296
Autor:
Khaled M. Hazzouri, Joan Blanchette, Sarah Daakour, Ashish Jaiswal, David R. Nobles, David R. Nelson, Amphun Chaiboonchoe, Bushra Saeed Dohai, Khaled M. A. Amiri, Julie Sexton, Alexandra Mystikou, Mark Hurd, Amnah Alzahmi, Kyle J. Lauersen, Michael Preston, Kourosh Salehi-Ashtiani, Weiqi Fu, Michael W. Lomas
Publikováno v:
Cell Host & Microbe .
Summary Being integral primary producers in diverse ecosystems, microalgal genomes could be mined for ecological insights, but representative genome sequences are lacking for many phyla. We cultured and sequenced 107 microalgae species from 11 differ
Autor:
Stephen J. Demosky, Joan Blanchette-Mackie, Ulrike H. Schueler, Christine R. Kaneski, John A. Hanover, Roscoe O. Brady, Alan T. Remaley, Nancy K. Dwyer
Publikováno v:
JIMD Reports ISBN: 9783662532775
Fabry disease is an X-linked sphingolipid storage disorder caused by a deficiency of the lysosomal enzyme α-galactosidase A (AGA, EC 3.2.1.22) resulting in the intracellular accumulation of globotriaosylceramide (Gb3). We found that Gb3 storage also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335c71cb691ac693f3dfec44f7ab2352
https://doi.org/10.1007/8904_2015_507
https://doi.org/10.1007/8904_2015_507
Autor:
Silvia Santamarina-Fojo, Nancy K. Dwyer, Christian A. Combs, Catherine L. Knapper, Joan Blanchette-Mackie, Stephen J. Demosky, Edward B. Neufeld, H. Bryan Brewer, John A. Stonik, Adele Cooney, Alan T. Remaley, Marcella E. Comly
Publikováno v:
Journal of Biological Chemistry. 279:15571-15578
We have previously established that the ABCA1 transporter, which plays a critical role in the lipidation of extracellular apolipoprotein acceptors, traffics between late endocytic vesicles and the cell surface (Neufeld, E. B., Remaley, A. T., Demosky
Autor:
Vargheese M. Chennathukuzhi, Peter McNamara, E. Joan Blanchette-Mackie, Jerome F. Strauss, Rossana Sapiro, Mei Zhang, Anne Marie Curtis, Jeff Bray, Zhibing Zhang, Maja Bucan, David Kapfhamer
Publikováno v:
Molecular and Cellular Biology. 22:7993-8004
cDNAs were cloned for the murine and human orthologues of Chlamydomonas PF20, a component of the alga axoneme central apparatus that is required for flagellar motility. The mammalian genes encode transcripts of 1.4 and 2.5 kb that are highly expresse
Autor:
Shiv Srivastava, Mei Sun, E. Joan Blanchette-Mackie, Judd W. Moul, Lanfeng Ma, Mei Zhang, Zhiqiang Zou, Jia Li, Linda Xu, Mazen Makarem, Gyorgy Petrovics, Wei Zhang, Isabell A. Sesterhenn
Publikováno v:
Molecular Medicine. 8:655-663
BACKGROUND: Deletion of chromosome 16q is frequently associated with diverse tumors. Numerous studies strongly suggest the presence of one or more tumor suppressor genes on chromosome 16q22 to 16qter including the widely studied cadherin gene family.
Autor:
Federico Martinez, John A. Hanover, M E Comly, Toshio Fujimoto, E. Joan Blanchette-Mackie, Pei Liu, Nancy K. Dwyer, Mei Zhang, Jerome F. Strauss, Lane K. Christenson
Publikováno v:
Journal of Biological Chemistry. 277:33300-33310
This study demonstrates that the steroidogenic acute regulatory protein-related lipid transfer (START) domain-containing protein, MLN64, participates in intracellular cholesterol trafficking. Analysis of the intracellular itinerary of MLN64 and MLN64
Autor:
M E Comly, Joan Blanchette-Mackie, Silvia Santamarina-Fojo, Adele Cooney, Edward B. Neufeld, Nancy K. Dwyer, Mei Zhang, John A. Stonik, Alan T. Remaley, H. Bryan Brewer, Stephen J. Demosky
Publikováno v:
Journal of Biological Chemistry. 276:27584-27590
ABCA1, the ATP-binding cassette protein mutated in Tangier disease, mediates the efflux of excess cellular sterol to apoA-I and thereby the formation of high density lipoprotein. The intracellular localization and trafficking of ABCA1 was examined in
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 214-225 (2000)
Combined lipase deficiency (cld) is a recessive mutation in mice that causes a severe lack of lipoprotein lipase (LPL) and hepatic lipase (HL) activities, hyperlipemia, and death within 3 days after birth. Earlier studies showed that inactive LPL and
Autor:
Jane M. Glick, Jerome F. Strauss, Shutish Patel, Hidemichi Watari, Peter G. Pentchev, E. Joan Blanchette-Mackie, Edward B. Neufeld, Gwo-Shing Sun, Nancy K. Dwyer
Publikováno v:
Experimental Cell Research. 255:56-66
Steroidogenic cells represent unique systems for the exploration of intracellular cholesterol trafficking. We employed cytochemical and biochemical methods to explore the expression, regulation, and function of the Niemann-Pick C1 protein (NPC1) in h