Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joan Backhouse"'
Autor:
L. F. Hill, G. A. Lumb, Priyadarshini de Silva, Joan Backhouse, S. W. Stanbury, E. Barbara Mawer, Carol M. Taylor
Publikováno v:
Clinical Science. 48:349-365
1. The metabolism of an intravenous pulse dose of double-isotope-labelled cholecalciferol has been studied in control subjects with widely differing states of vitamin D nutrition and in patients with primary disorders of parathyroid function. 2. The
Publikováno v:
The Lancet. 307:1203-1206
In four healthy controls and three patients with hypoparathyroidism serum-1,25-dihydroxycholecalciferol (1,25-D.H.C.C.) concentrations, after oral or intravenous administration, declined biphasically with a rapid-phase half-time of about 14 hours. Re
Publikováno v:
Clinical Science. 43:413-431
1. The distribution of vitamin D and its metabolites in human tissues has been studied by the combined use of radioactive cholecalciferol and biological assays of antiricketic activity in tissue extracts. 2. Injected radioactive cholecalciferol was c
Publikováno v:
Nature: New biology. 232(2)
EXPERIMENTS of Kodicek et al.1–5 have demonstrated a new metabolite of vitamin D in the intestinal mucosa of rat and chick, and have culminated in its chemical identification as 1,25-dihydroxycholecalciferol2. This metabolite has high biological po
Publikováno v:
Lancet (London, England). 1(7804)
1,25-dihydroxycholecalciferol (1,25- D.H.C.C.) could not be detected in the serum of patients with chronic renal insufficiency after injection of radioactive cholecalciferol. These patients were comparable in degree of vitamin-D deficiency with contr