Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Joan Tilburn"'
1
Refining the pH response in A spergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein
Autor: Herbert N. Arst, Lynne Rainbow, Maria M Peñas-Parilla, Henk-Jan Bussink, Elaine Bignell, Daniel Lucena-Agell, Eduardo A. Espeso, Susana Negrete-Urtasun, Joanna D. Rudnicka, Claudio Scazzocchio, Miguel A. Peñalva, Joan Tilburn, Tatiana Múnera-Huertas, Margherita Bertuzzi
Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 2015, 98 (6), pp.1051-72. ⟨10.1111/mmi.13173⟩
Molecular Microbiology, 2015, 98 (6), pp.1051-72. ⟨10.1111/mmi.13173⟩
Molecular Microbiology, Wiley, 2015, 98 (6), pp.1051-72. 〈10.1111/mmi.13173〉
International audience; The Aspergillus nidulans PacC transcription factor mediates gene regulation in response to alkaline ambient pH which, signalled by the Pal pathway, results in the processing of PacC(72) to PacC(27) via PacC(53). Here we invest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e459377aebf1eecce959bf04a352b2
http://europepmc.org/articles/PMC4832277
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2
Ambient pH gene regulation in fungi: making connections
Autor: Herbert N. Arst, Elaine Bignell, Miguel A. Peñalva, Joan Tilburn
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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10 páginas, 3 figuras, I figura, 1 tabla -- PAGS nros. 291-300
Many fungi grow over a wide pH range and their gene expression is tailored to the environmental pH. In Aspergillus nidulans, the transcription factor PacC, an activator of genes exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0d56b535cc584a6f1343df4a32d1c8
https://doi.org/10.1016/j.tim.2008.03.006
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3
Nonsense-Mediated mRNA Decay Mutation in Aspergillus nidulans
Autor: Susana Negrete-Urtasun, Igor Y. Morozov, Mark X. Caddick, Herbert N. Arst, Joan Tilburn, Christine A. Jansen
Publikováno v: Eukaryotic Cell. 5:1838-1846
An Aspergillus nidulans mutation, designated nmdA1 , has been selected as a partial suppressor of a frameshift mutation and shown to truncate the homologue of the Saccharomyces cerevisiae nonsense-mediated mRNA decay (NMD) surveillance component Nmd2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001390147932b64dffdc083e7a3389c4
https://doi.org/10.1128/ec.00220-06
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4
Mutational Analysis of the pH Signal Transduction Component PalC of Aspergillus nidulans Supports Distant Similarity to BRO1 Domain Family Members
Autor: Miguel A. Peñalva, Herbert N. Arst, Joan Tilburn, Elena Reoyo, Juan C. Sánchez-Ferrero
Publikováno v: Genetics. 171:393-401
The alkaline ambient pH signal transduction pathway component PalC has no assigned molecular role. Therefore we attempted a gene-specific mutational analysis and obtained 55 new palC loss-of-function alleles including 24 single residue substitutions.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee259bbd8d1bb2a23fe617d8d0b105b6
https://doi.org/10.1534/genetics.105.044644
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6
Specificity Determinants of Proteolytic Processing of Aspergillus PacC Transcription Factor Are Remote from the Processing Site, and Processing Occurs in Yeast If pH Signalling Is Bypassed
Autor: Eduardo A. Espeso, Joan Tilburn, Miguel A. Peñalva, Elaine Bignell, Mark X. Caddick, Christopher V. Brown, David A. Widdick, José Manuel Mingot, Margarita Orejas, Eliecer Díez, Sovan Sarkar, Herbert N. Arst
Publikováno v: ResearcherID
Scopus-Elsevier
The Aspergillus nidulans transcription factor PacC, which mediates pH regulation, is proteolytically processed to a functional form in response to ambient alkaline pH. The full-length PacC form is unstable in the presence of an operational pH signal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a004a6f877c36ce8ad304fceaac357e1
https://doi.org/10.1128/mcb.19.2.1390
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7
Putative membrane components of signal transduction pathways for ambient pH regulation inAspergillusand meiosis inSaccharomycesare homologous
Autor: Steven H. Denison, Wendy A. Mayer, Joan Tilburn, Susana Negrete-Urtasun, Alpa Goel, José Manuel Mingot, Herbert N. Arst, Miguel A. Peñalva, Eduardo A. Espeso
Publikováno v: Molecular Microbiology. 30:259-264
The zinc finger regions of the Aspergillus nidulans PacC transcription factor, mediating regulation of gene expression by ambient pH, and the Saccharomyces cerevisiae Rim1p transcription factor, mediating control of meiosis and invasiveness, are homo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9478626ddb761cb680a99d606fea467
https://doi.org/10.1046/j.1365-2958.1998.01058.x
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8
Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety
Autor: Joan Tilburn, Margarita Orejas, Sovan Sarkar, Miguel A. Peñalva, Eduardo A. Espeso, Herbert N. Arst
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Extremes of pH are an occupational hazard for many microorganisms. In addition to efficient pH homeostasis, survival effectively requires a regulatory system tailoring the syntheses of molecules functioning beyond the cell boundaries (permeases, secr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1d38ecc068c96118f13ebd2dc1781f
https://doi.org/10.1101/gad.9.13.1622
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9
pH regulation of penicillin production inAspergillus nidulans
Autor: Maxwell W. Adlard, Joan Tilburn, Ajit J. Shah, Herbert N. Arst
Publikováno v: FEMS Microbiology Letters. 77:209-212
As shown by both bioassay and high-performance liquid chromatographic (HPLC) analysis, penicillin G production by Aspergillus nidulans is subject to regulation by the pH of the growth medium. Penicillin titres were highest at alkaline pH and in strai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::508979012470f271d28c75b770529887
https://doi.org/10.1111/j.1574-6968.1991.tb04349.x
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10
Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH
Autor: Eduardo A. Espeso, Ana María Calcagno-Pizarelli, América Hervás-Aguilar, Joanna D. Rudnicka, Steven H. Denison, Miguel A. Peñalva, Henk-Jan Bussink, Susana Negrete-Urtasun, Tatiana Múnera-Huertas, Joan Tilburn, Herbert N. Arst, Ljiljana Stanton
Publikováno v: Eukaryotic cell. 6(12)
The Aspergillus nidulans ambient pH signaling pathway involves two transmembrane domain (TMD)-containing proteins, PalH and PalI. We provide in silico and mutational evidence suggesting that PalI is a three TMD (3-TMD) protein with an N-terminal sign
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b83a02a33e164ebb0404f63f4b7d37
https://pubmed.ncbi.nlm.nih.gov/17951518
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