Roles of avian herpesvirus microRNAs in infection, latency, and oncogenesis

Autor: Joan Burnside, Robin W. Morgan

Publikováno v: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1809:654-659

MicroRNAs have been reported for the avian herpesviruses Marek's disease virus 1 (MDV1; oncogenic), Marek's disease virus 2 (MDV2; non-oncogenic), herpesvirus of turkeys (HVT), and infectious laryngotracheitis virus (ILTV). No obvious phylogenetic re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f11f4bef92d8ef1b5f674821db9eaba
https://doi.org/10.1016/j.bbagrm.2011.06.001

Sequence Conservation and Differential Expression of Marek's Disease Virus MicroRNAs

Autor: Sachin Kamboj, Grace Isaacs, Joan Burnside, Robin W. Morgan, Pamela J. Green, Blake C. Meyers, Amy S. Anderson, Grace Lagasse, Erin L. Bernberg, Mark S. Parcells, Emily Huang

Publikováno v: Journal of Virology. 82:12213-12220

Marek's disease virus (MDV), a herpesvirus that causes a lymphoproliferative disorder in chickens, encodes a number of microRNAs derived primarily from two locations in the MDV genome. One cluster of microRNA genes flanks the meq oncogene, and a seco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde77eaf0eabc82ba9a51eeffe35f24d
https://doi.org/10.1128/jvi.01722-08

Functional Genomics of the Chicken—A Model Organism

Autor: Michel J. Duclos, J. J. Zhu, Joan Burnside, Shane C. Burgess, Jerry B. Dodgson, Tom E. Porter, Jean Simon, Larry A. Cogburn, Hans H. Cheng

Publikováno v: Poultry Science. 86:2059-2094

Since the sequencing of the genome and the development of high-throughput tools for the exploration of functional elements of the genome, the chicken has reached model organism status. Functional genomics focuses on understanding the function and reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d706484b88f06306f193d33b7adae2e
https://doi.org/10.1093/ps/86.10.2059

Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate

Autor: Harrie L. Glansbeek, Joan Burnside, John R. Young, Andrew C. Gill, Lawrence G. Hunt, Clive A. Tregaskes

Publikováno v: Tregaskes, C A, Glansbeek, H L, Gill, A C, Hunt, L G, Burnside, J & Young, J R 2005, ' Conservation of biological properties of the CD40 ligand, CD154 in a non-mammalian vertebrate ', Developmental and Comparative Immunology, vol. 29, no. 4, pp. 361-374 . https://doi.org/10.1016/j.dci.2004.09.001

Signals delivered by the CD40 ligand, CD154, have crucial roles in immune responses in mammals, being required for development of germinal centres, maturation of T-dependent antibody responses, and generation of B-cell memory. To determine whether th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5822581b823d1f3aa2a39afe58991fb7
https://doi.org/10.1016/j.dci.2004.09.001

Identification and Molecular Cloning of Functional Chicken IL-12

Autor: Virgil E.J.C. Schijns, Joan Burnside, Nancy van Daal, Winfried G J Degen, Hanneke I. van Zuilekom

Publikováno v: The Journal of Immunology. 172:4371-4380

By a combination of large-scale sequencing, bioinformatics, and traditional molecular biology, we identified the long-searched-for cDNA sequences encoding the homologues of the chicken IL-12p35 and IL-12p40 chains. These molecules are the first disco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b94aba1cd3d29d074fc73821595443
https://doi.org/10.4049/jimmunol.172.7.4371