Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Joachim Weber"'
Development of a Trusted Third Party at a Large University Hospital: Design and Implementation Study
Autor:
Eric Wündisch, Peter Hufnagl, Peter Brunecker, Sophie Meier zu Ummeln, Sarah Träger, Marcus Kopp, Fabian Prasser, Joachim Weber
Publikováno v:
JMIR Medical Informatics, Vol 12, Pp e53075-e53075 (2024)
Abstract BackgroundPseudonymization has become a best practice to securely manage the identities of patients and study participants in medical research projects and data sharing initiatives. This method offers the advantage of not requiring the dire
Externí odkaz:
https://doaj.org/article/194ae887c5d344289cd34a42ce72f875
Autor:
Nghi N. B. Tran, A. T. A. Bui, Valeria Jaramillo-Martinez, Joachim Weber, Qinghai Zhang, Ina L. Urbatsch
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
P-glycoprotein (Pgp) is a multidrug transporter that uses the energy from ATP binding and hydrolysis to export from cells a wide variety of hydrophobic compounds including anticancer drugs, and mediates the bioavailability and pharmacokinetics of man
Externí odkaz:
https://doaj.org/article/5e99138aefd547a4832f74f691dcce64
Autor:
Jan-Erik Guelker, Yoshihisa Kinoshita, Joachim Weber-Albers, Alexander Bufe, Christian Blockhaus, Kambis Mashayekhi
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 38, Iss , Pp 100942- (2022)
Background: The new EuroCTO CASTLE Score was validated against the widely adopted Japanese Multicenter CTO Registry (J-CTO) score in predicting technical success in percutaneous coronary intervention (PCI) for coronary chronic total occlusions (CTO).
Externí odkaz:
https://doaj.org/article/6c174f2688d34995ba96fd680b202cec
Autor:
Nelli Mnatsakanyan, Marc C. Llaguno, Youshan Yang, Yangyang Yan, Joachim Weber, Fred J. Sigworth, Elizabeth A. Jonas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The ATP synthase has been suggested to contain the mitochondrial permeability transition pore (mPTP), which has a crucial role in cell death. Here the authors show that reconstituted ATP synthase monomers form voltage-gated and Ca2+ -activated channe
Externí odkaz:
https://doaj.org/article/1114e6356c4045608f3cc3526a4d63ca
Autor:
Luis Pablo Avila-Barrientos, Luis Fernando Cofas-Vargas, Guillermin Agüero-Chapin, Enrique Hernández-García, Sergio Ruiz-Carmona, Norma A. Valdez-Cruz, Mauricio Trujillo-Roldán, Joachim Weber, Yasser B. Ruiz-Blanco, Xavier Barril, Enrique García-Hernández
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 557 (2022)
With the uncontrolled growth of multidrug-resistant bacteria, there is an urgent need to search for new therapeutic targets, to develop drugs with novel modes of bactericidal action. FoF1-ATP synthase plays a crucial role in bacterial bioenergetic pr
Externí odkaz:
https://doaj.org/article/db2affc2047141aab1e191d534aab100
Autor:
Joachim Weber
Publikováno v:
Promet (Zagreb), Vol 15, Iss 4, Pp 271-275 (2003)
A giant new deep water container terminal in Germany, theproject of the "Jade- Weser-port" is being pushed forward by differentactors in German shipping and transport politics. The articlediscusses the possibilities, the pros and cons of such a proje
Externí odkaz:
https://doaj.org/article/edbc55d880d6498686ddf51c8f327cc9
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Autor:
Nelli Mnatsakanyan, Han-A Park, Jing Wu, Xiang He, Marc C. Llaguno, Maria Latta, Paige Miranda, Besnik Murtishi, Morven Graham, Joachim Weber, Richard J. Levy, Evgeny V. Pavlov, Elizabeth A. Jonas
Publikováno v:
Cell Death & Differentiation. 29:1874-1887
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Publikováno v:
Rock Mechanics and Rock Engineering. 54:2615-2641
This study introduces “biogeomechanics”, an emerging field of geotechnics, as a resourceful approach in assessing the impact of biological processes on the mechanical properties and behavior of geomaterials. Here, we investigated the localized an
Autor:
Hauke Baumann, Katja Lohmann, Simone Zittel, Hauke Busch, Christine Klein, Vladimir S. Kostic, Michaela Trilck-Winkler, Frank J. Kaiser, Philip Seibler, Alexander Münchau, Fabian Ott, Joachim Weber
Publikováno v:
Movement Disorders. 36:1381-1391
Background The THAP1 gene encodes a transcription factor, and pathogenic variants cause a form of autosomal dominant, isolated dystonia (DYT-THAP1) with reduced penetrance. Factors underlying both reduced penetrance and the disease mechanism of DYT-T
Autor:
Christine Klein, Katja Lohmann, Evelyn Knappe, Neele Kuhnke, Philip Seibler, Joachim Weber, Peter P. Urban, Sylvie Delcambre, Tillman Vollbrandt, Sokhna Haissatou Diaw, Joanne Trinh, Anne Grünewald, Inke R. König, Patrycja Kupnicka, Frauke Hinrichs, Marija Dulovic-Mahlow, Lena-Christin Ingwersen, Alexander Balck
Publikováno v:
Annals of Neurology. 89:158-164
Objective Even though genetic predisposition has proven to be an important element in Parkinson's disease (PD) etiology, monozygotic (MZ) twins with PD displayed a concordance rate of only about 20% despite their shared identical genetic background.