Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes

Autor: Karl-Heinz Merz, Dieter Schrenk, Lan Gao, Hans-Joachim Schmitz

Publikováno v: Toxicology Letters. 311:91-97

Phytomedicinal preparations containing extracts of the plant Chelidonium majus (Greater Celandine) have been used in the therapy of upper abdominal disorders. C. majus alkaloids (CAL) were suspected to be responsible for reported cases of liver sympt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c8848e1d5be7bab80a6cca1a67642d
https://doi.org/10.1016/j.toxlet.2019.04.031

Aroma Characterization and Safety Assessment of a Beverage Fermented by Trametes versicolor

Autor: Marco A. Fraatz, Hans-Joachim Schmitz, Holger Zorn, Dieter Schrenk, Florian Birk, Yanyan Zhang, Julia Müller

Publikováno v: Journal of Agricultural and Food Chemistry. 63:6915-6921

A cereal-based beverage was developed by fermentation of wort with the basidiomycete Trametes versicolor. The beverage possessed a fruity, fresh, and slightly floral aroma. The volatiles of the beverage were isolated by liquid-liquid extraction (LLE)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82b25a71aa773149c99e7d4995339c1
https://doi.org/10.1021/acs.jafc.5b02167

Hepatic effects of a highly purified 2,2′,3,4,4′,5,5′-heptachlorbiphenyl (PCB 180) in male and female rats

Autor: Hans-Joachim Schmitz, Päivi Heikkinen, Krister Halldin, Patrik L. Andersson, Heather A. Leslie, Timo Hamers, Helen Hǻkansson, Matti Viluksela, Gerd Hamscher, Emma Westerholm, Satu Sankari, Dieter Schrenk, Robert Roos, Marjo Niittynen, Merja Korkalainen, Leo T.M. van der Ven

Publikováno v: Toxicology, 284(1-3), 42-53. Elsevier Ireland Ltd
Roos, R, Andersson, P L, Halldin, K, Håkansson, H, Westerholm, E, Hamers, T H M, Hamscher, G, Heikkinen, P, Korkolainen, M, Leslie, H A, Niitynen, N, Sankari, S, Schmitz, H J, van der Ven, L, Viluksela, M & Schrenk, D 2011, ' Hepatic effects of a highly purified 2,2’,3,4,4’,5,5’-heptachlorobiphenyl (PCB-180) in male and female rats ', Toxicology, vol. 284, no. 1-3, pp. 42-53 . https://doi.org/10.1016/j.tox.2011.03.013

PCB 180 (2,2',3,4,4',5,5'-heptachlorobiphenyl) is a persistent and accumulating polychlorinated biphenyl abundantly present in food and the environment. In this study, we used highly purified PCB 180 (dioxinlike impurities: 2.7 ng TEQ(WHO)/g PCB 180)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3c7f92f33a9793dde403f8a330d5dc
https://doi.org/10.1016/j.tox.2011.03.013

Posters

Autor: F. Dal Bello, J. Walter, C. Hertel, W. P Hammes, G. Festag, N. Haag, Gabriele Beyer‐Sehlmeyer, M. N. Ebert, B. Marian, Eva Gietl, Annett Klinder, Stella Pistoli, R. Goralczyk, H. Bachmann, G. Riss, C‐P. Aebischer, B. Lenz, A. Kampkötter, E. Röhrdanz, K. Iwami, S. Ohler, W. Wätjen, Y. Chovolou, S. E. Kulling, R. Kahl, D. Kavvadias, P. Sand, P. Riederer, E. Richling, P. Schreier, Peter P. Hoppe, Klaus Kraemer, Henk van den Berg, Gery Steenge, Trinette van Vliet, S. Lebrun, H. Schulze, W. Föllmann, Leane Lehmann, P. Niering, I. Köhler, Q.‐H. Tran‐Thi, Erika Pfeiffer, Harald L. Esch, Simone Höhle, Aniko M. Solyom, Barbara N. Timmermann, Manfred Metzler, W. Seefelder, N. Bartke, T. Gronauer, S. Fischer, H.‐U. Humpf, S. Schäfer, H.G. Kamp, C. Müller, B. Haber, G. Eisenbrand, C. Janzowski, K. Wertz, P. Buchwald, T. Hansen, M. Niehof, M. Dangers, J. Borlak, Stefanie Klenow, Michael Glei, Bernd Haber, Beatrice L. Pool‐Zobel, Annette Baumgart, Melanie Schmidt, Hans‐Joachim Schmitz, Dieter Schrenk, Achim Bub, Bernhard Watzl, M. Roller, G. Caderni, G. Rechkemmer, Karlis Briviba, Kerstin Schnäbele, Elke Schwertle, Kerstin Rebscher, Stephan W. Barth, Silvia Roser, Heike Lang, Anette Höll, Sabine Guth, Doris Marko, Monika Kemény, Michael Habermeyer, Edda Bernardy, Susanne Meiers, Ulrike Weyand

Publikováno v: Functional Food: Safety Aspects. :279-375

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77ec3f01f51f9a5d9644b35a2e653e33
https://doi.org/10.1002/3527606130.ch6

Inhibition of apoptosis in rat hepatocytes treated with 'non-dioxin-like' polychlorinated biphenyls

Autor: Barbara Wagner, Dieter Schrenk, Hans-Joachim Schmitz, Stefan Bohnenberger

Publikováno v: Carcinogenesis. 22:1601-1605

Polychlorinated biphenyls (PCBs) are among the most prominent persistent environmental pollutants exhibiting neurotoxic, teratogenic and tumour-promoting effects in experimental animals. 'Dioxin-like' properties have been assigned to a number of PCBs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21861c17227b44eb25240b2cd911c86c
https://doi.org/10.1093/carcin/22.10.1601