Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joachim Rehbock"'
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 136:1369-1375
Abrogation of the function of TP53 gene is supposed to lead to a more aggressive breast cancer phenotype that produces a less favorable clinical outcome. The p21 gene on chromosome 6p21.2 can be stimulated by an activated TP53 gene. A product of tran
Autor:
Marianne Jochum, Elisabeth Schremmer-Danninger, Michael J. Flaig, Alexander Faussner, Edwin Fink, Joachim Rehbock, Matthias C. Raggi, Dorit K. Nägler, Kerstin Miska
Publikováno v:
International Immunopharmacology. 7:103-112
Bradykinin and its kinin B(2) receptor are autocrine and paracrine mediators in foetal membranes and decidua. As a first step we characterized the intracellular morphology of decidual cells. Cultured decidua tissue-derived cells immunolabel for vimen
Autor:
Richard Reneland, Richard B. Roth, Ulrike Schwarz-Boeger, Stefan Kammerer, Andreas Braun, Lyn R. Griffiths, Marion Kiechle, Carolyn R. Hoyal, Matthew R. Nelson, Florian Ebner, Charles R. Cantor, Joachim Rehbock, George Marnellos
Publikováno v:
Proceedings of the National Academy of Sciences. 102:2004-2009
The development of breast cancer is a complex process that involves multiple genes at many stages, from initial cell cycle dysregulation to disease progression. To identify genetic variations that influence this process, we conducted a large-scale as
Autor:
Joachim Rehbock, Peter Buchinger
Publikováno v:
Seminars in Thrombosis and Hemostasis. 25:543-549
Bacterial infection of the amniotic cavity is one of the most frequent causes of preterm delivery. Bacterial products activate a network of autocrine and paracrine mediators in fetal membranes and decidua, with prostaglandins finally inducing contrac
Publikováno v:
Immunopharmacology. 43:235-239
Aspects of the pathophysiological steps leading to preterm labor after intrauterine infection can be studied in a cell culture model of decidua-derived cells. In this model, bradykinin (BK) increases the release of arachidonic acid (AA), the precurso
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 104:495-499
Cytokines are known to participate in the process of parturition within a paracrine network in fetal membranes. Bradykinin can also contribute to this process, increasing the release of eicosanoids from decidua cells. In this study, we present eviden
Autor:
Carolyn R, Hoyal, Stefan, Kammerer, Richard B, Roth, Richard, Reneland, George, Marnellos, Marion, Kiechle, Ulrike, Schwarz-Boeger, Lyn R, Griffiths, Florian, Ebner, Joachim, Rehbock, Matthew R, Nelson, Andreas, Braun
Publikováno v:
Journal of Carcinogenesis, Vol 4, Iss 1, p 13 (2005)
Journal of Carcinogenesis
Journal of Carcinogenesis
Background Several studies have identified rare genetic variations responsible for many cases of familial breast cancer but their contribution to total breast cancer incidence is relatively small. More common genetic variations with low penetrance ha
Autor:
Richard B. Roth, Josephine M. Atienza, Jonas Ekblom, Stefan Kammerer, Kevin J. Smylie, Mikhail F. Denissenko, Caridad Rosette, Joachim Rehbock
Publikováno v:
Molecular cancer therapeutics. 4(3)
A genome-wide case-control association study done in our laboratory has identified a single nucleotide polymorphism located in RAD21 as being significantly associated with breast cancer susceptibility. RAD21 is believed to function in sister chromati
Publikováno v:
Immunopharmacology. 33:164-166
In vitro studies on cultured human decidual cells present evidence for the expression of the bradykinin B2 receptor. This protein was localized by immunocytochemical methods at the cellular plasma membrane and the mRNA was found in cellular extracts
Autor:
Christian Ulbrich, Gerhard Forster, Marion Kiechle, Richard B. Roth, Charles R. Cantor, Peter Meyer, George Marnellos, Stefan Kammerer, Joachim Rehbock, Georg M. Praetorius, Andreas Braun, Lyn R. Griffiths, Richard Reneland, Nathan J. Markward, Matthew R. Nelson, Carolyn R. Hoyal, Florian Ebner, Korbinian Chrobok, Ulrike Schwarz-Boeger
Publikováno v:
Cancer research. 64(24)
We conducted a large-scale association study to identify genes that influence nonfamilial breast cancer risk using a collection of German cases and matched controls and >25,000 single nucleotide polymorphisms located within 16,000 genes. One of the c